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EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

Nature communications, 2017-06, Vol.8 (1), p.15773-15773, Article 15773

2017

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Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Nature communications, 2018-09, Vol.9 (1), p.3815-17, Article 3815

2018

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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer

The Journal of clinical investigation, 2018-04, Vol.128 (4), p.1283-1299

2018

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Landscape analysis of adjacent gene rearrangements reveals BCL2L14–ETV6 gene fusions in more aggressive triple-negative breast cancer

Proceedings of the National Academy of Sciences - PNAS, 2020-05, Vol.117 (18), p.9912-9921

2020

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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (33), p.13820-13825

2009

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gpGrouper: A Peptide Grouping Algorithm for Gene-Centric Inference and Quantitation of Bottom-Up Proteomics Data

Molecular & cellular proteomics, 2018-11, Vol.17 (11), p.2270-2283

2018

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STAT3 Signaling Is Activated Preferentially in Tumor‐Initiating Cells in Claudin‐Low Models of Human Breast Cancer

Stem cells (Dayton, Ohio), 2014-10, Vol.32 (10), p.2571-2582

2014

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MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade

Nature communications, 2022-01, Vol.13 (1), p.245-245, Article 245

2022

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Cisplatin@US-tube carbon nanocapsules for enhanced chemotherapeutic delivery

Biomaterials, 2012-02, Vol.33 (5), p.1455-1461

2012

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A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud

PLoS computational biology, 2016-04, Vol.12 (4), p.e1004839-e1004839

2016

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Deconvolution of cancer cell states by the XDec-SM method

PLoS computational biology, 2023-08, Vol.19 (8), p.e1011365-e1011365

2023

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Paracrine Wnt signaling both promotes and inhibits human breast tumor growth

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6991-6996

2013

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Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells

PloS one, 2010-08, Vol.5 (8), p.e12180

2010

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The Terminal End Bud: the Little Engine that Could

Journal of mammary gland biology and neoplasia, 2017-06, Vol.22 (2), p.93-108

2017

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Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation

Cell reports (Cambridge), 2015-07, Vol.12 (3), p.511-524

2015

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Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail

Molecular and Cellular Biology, 2007-04, Vol.27 (8), p.3165-3175

2007

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Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

BMC cancer, 2019-03, Vol.19 (1), p.220-220, Article 220

2019

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Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia

Development (Cambridge), 2007-03, Vol.134 (6), p.1231-1242

2007

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The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer

Cold Spring Harbor perspectives in medicine, 2024-04, Vol.14 (4)

2024

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New paradigms for the Hedgehog signaling network in mammary gland development and breast Cancer

Biochimica et biophysica acta. Reviews on cancer, 2017-08, Vol.1868 (1), p.315-332

2017

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Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model

PloS one, 2012-08, Vol.7 (8), p.e30207-e30207

2012

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Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

Breast cancer research : BCR, 2015-01, Vol.17 (1), p.3-3, Article 3

2015

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Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer

EMT cells increase breast cancer metastasis via paracrine GLI activation in neighbouring tumour cells

Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer

Landscape analysis of adjacent gene rearrangements reveals BCL2L14–ETV6 gene fusions in more aggressive triple-negative breast cancer

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

gpGrouper: A Peptide Grouping Algorithm for Gene-Centric Inference and Quantitation of Bottom-Up Proteomics Data

STAT3 Signaling Is Activated Preferentially in Tumor‐Initiating Cells in Claudin‐Low Models of Human Breast Cancer

MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade

Cisplatin@US-tube carbon nanocapsules for enhanced chemotherapeutic delivery

A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud

Deconvolution of cancer cell states by the XDec-SM method

Combinatorial inhibition of PTPN12-regulated receptors leads to a broadly effective therapeutic strategy in triple-negative breast cancer

Paracrine Wnt signaling both promotes and inhibits human breast tumor growth

Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cells

The Terminal End Bud: the Little Engine that Could

Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation

Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail

Circulating tumor cell investigation in breast cancer patient-derived xenograft models by automated immunofluorescence staining, image acquisition, and single cell retrieval and analysis

Constitutive activation of smoothened (SMO) in mammary glands of transgenic mice leads to increased proliferation, altered differentiation and ductal dysplasia

RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer

The Power and Promise of Patient-Derived Xenografts of Human Breast Cancer

New paradigms for the Hedgehog signaling network in mammary gland development and breast Cancer

Selective small molecule Stat3 inhibitor reduces breast cancer tumor-initiating cells and improves recurrence free survival in a human-xenograft model

Circulating and disseminated tumor cells from breast cancer patient-derived xenograft-bearing mice as a novel model to study metastasis

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