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Tyrosine Kinase Inhibitors: Views of Selectivity, Sensitivity, and Clinical Performance

Annual review of pharmacology and toxicology, 2013-01, Vol.53 (1), p.161-185

LEVITZKI, Alexander

2013

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Tyrphostins and other tyrosine kinase inhibitors

Annual review of biochemistry, 2006-01, Vol.75 (1), p.93-109

2006

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Targeting the EGFR and the PKB pathway in cancer

Current opinion in cell biology, 2009-04, Vol.21 (2), p.185-193

2009

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Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (14), p.4383-4394

2013

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ROS, stress-activated kinases and stress signaling in cancer

EMBO reports, 2002-05, Vol.3 (5), p.420-425

2002

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Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks

Molecular cancer therapeutics, 2018-05, Vol.17 (5), p.931-942

2018

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Oncogene, 2001-05, Vol.20 (20), p.2499-2513

2001

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Tyrosine Kinase Inhibition: An Approach to Drug Development

Science (American Association for the Advancement of Science), 1995-03, Vol.267 (5205), p.1782-1788

1995

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Cisplatin-induced activation of the EGF receptor

Oncogene, 2002-12, Vol.21 (57), p.8723-8731

2002

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Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF

PloS one, 2016-09, Vol.11 (9), p.e0162321

2016

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Information-theoretic analysis of phenotype changes in early stages of carcinogenesis

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (22), p.10324-10329

2010

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Enhanced ROS Production in Oncogenically Transformed Cells Potentiates c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Activation and Sensitization to Genotoxic Stress

Molecular and Cellular Biology, 2001-10, Vol.21 (20), p.6913-6926

2001

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My journey from tyrosine phosphorylation inhibitors to targeted immune therapy as strategies to combat cancer

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (24), p.11579-11586

2019

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EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

PLoS medicine, 2006-01, Vol.3 (1), p.e6

2006

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Development of New Insulin-like Growth Factor-1 Receptor Kinase Inhibitors Using Catechol Mimics

The Journal of biological chemistry, 2003-10, Vol.278 (42), p.40442-40454

2003

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On a fundamental structure of gene networks in living cells

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4702-4707

2012

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Heterogeneity of gene expression in murine squamous cell carcinoma development-the same tumor by different means

PloS one, 2013-03, Vol.8 (3), p.e57748

2013

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Tyrphostins : tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction

The FASEB journal, 1992-11, Vol.6 (14), p.3275-3282

LEVITZKI, A

1992

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Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Immunity (Cambridge, Mass.), 1999, Vol.10 (1), p.105-115

1999

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Substrate Competitive Inhibitors of IGF-1 Receptor Kinase

Biochemistry (Easton), 2000-12, Vol.39 (51), p.15705-15712

2000

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Anomalous features of EMT during keratinocyte transformation

PloS one, 2008-02, Vol.3 (2), p.e1574

2008

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Protein Kinase Inhibitors as a Therapeutic Modality

Accounts of chemical research, 2003-06, Vol.36 (6), p.462-469

Levitzki, Alexander

2003

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Signal transduction therapy of cancer

Molecular aspects of medicine, 2010-08, Vol.31 (4), p.287-329

2010

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Shift from Apoptotic to Necrotic Cell Death during Human Papillomavirus-induced Transformation of Keratinocytes

The Journal of biological chemistry, 2009-04, Vol.284 (17), p.11717-11727

2009

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Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR

Nature biotechnology, 2002-09, Vol.20 (9), p.895-900

2002

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Tyrosine Kinase Inhibitors: Views of Selectivity, Sensitivity, and Clinical Performance

Tyrphostins and other tyrosine kinase inhibitors

Targeting the EGFR and the PKB pathway in cancer

Therapeutic Destruction of Insulin Receptor Substrates for Cancer Treatment

ROS, stress-activated kinases and stress signaling in cancer

Impact of the Anticancer Drug NT157 on Tyrosine Kinase Signaling Networks

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

Tyrosine Kinase Inhibition: An Approach to Drug Development

Cisplatin-induced activation of the EGF receptor

Targeting polyIC to EGFR over-expressing cells using a dsRNA binding protein domain tethered to EGF

Information-theoretic analysis of phenotype changes in early stages of carcinogenesis

Enhanced ROS Production in Oncogenically Transformed Cells Potentiates c-Jun N-Terminal Kinase and p38 Mitogen-Activated Protein Kinase Activation and Sensitization to Genotoxic Stress

My journey from tyrosine phosphorylation inhibitors to targeted immune therapy as strategies to combat cancer

EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice

Development of New Insulin-like Growth Factor-1 Receptor Kinase Inhibitors Using Catechol Mimics

On a fundamental structure of gene networks in living cells

Heterogeneity of gene expression in murine squamous cell carcinoma development-the same tumor by different means

Tyrphostins : tyrosine kinase blockers as novel antiproliferative agents and dissectors of signal transduction

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

Substrate Competitive Inhibitors of IGF-1 Receptor Kinase

Anomalous features of EMT during keratinocyte transformation

Protein Kinase Inhibitors as a Therapeutic Modality

Signal transduction therapy of cancer

Shift from Apoptotic to Necrotic Cell Death during Human Papillomavirus-induced Transformation of Keratinocytes

Inhibition of glioma growth by tumor-specific activation of double-stranded RNA-dependent protein kinase PKR

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