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Evaluation of the TruSight Oncology 500 Assay for Routine Clinical Testing of Tumor Mutational Burden and Clinical Utility for Predicting Response to Pembrolizumab

The Journal of molecular diagnostics : JMD, 2022-06, Vol.24 (6), p.600-608

2022

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Pre-Analytical Considerations for Successful Next-Generation Sequencing (NGS): Challenges and Opportunities for Formalin-Fixed and Paraffin-Embedded Tumor Tissue (FFPE) Samples

International journal of molecular sciences, 2016-09, Vol.17 (9), p.1579-1579

2016

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Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Molecular neurodegeneration, 2017-05, Vol.12 (1), p.39-16, Article 39

2017

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Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation

Biochemical journal, 2006-09, Vol.398 (3), p.423-430

2006

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Data Interoperability of Whole Exome Sequencing (WES) Based Mutational Burden Estimates from Different Laboratories

International journal of molecular sciences, 2016-04, Vol.17 (5), p.651-651

2016

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Perforating foreign body in the ventriculus of an umbrella cockatoo (Cacatua alba)

Journal of avian medicine and surgery, 2013-06, Vol.27 (2), p.128-135

2013

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Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects gene expression pathways beyond cholesterol metabolism in liver cells

Journal of cellular physiology, 2010-07, Vol.224 (1), p.273-281

2010

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Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab

NPJ precision oncology, 2024-09, Vol.8 (1), p.204-9, Article 204

2024

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80 Evaluation of the trusight oncology 500 assay for routine clinical testing of tumor mutational burden (TMB) and clinical utility for predicting response to pembrolizumab

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A49-A50

2020

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Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans

Biochimica et biophysica acta, 2007-09, Vol.1770 (9), p.1345-1351

2007

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Assessment of Normal and Mutant Human Presenilin Function in Caenorhabditis elegans

Proceedings of the National Academy of Sciences - PNAS, 1996-12, Vol.93 (25), p.14940-14944

1996

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The Caenorhabditis elegans homolog of the putative prostate cancer susceptibility gene ELAC2, hoe-1, plays a role in germline proliferation

Developmental biology, 2004-02, Vol.266 (1), p.151-160

2004

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PS1 N- and C-Terminal Fragments Form a Complex That Functions in APP Processing and Notch Signaling

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (21), p.12186-12190

2001

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Letermovir Resistance Analysis in a Clinical Trial of Cytomegalovirus Prophylaxis for Hematopoietic Stem Cell Transplant Recipients

The Journal of infectious diseases, 2020-03, Vol.221 (7), p.1117-1126

2020

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Measuring Tumor Mutational Burden (TMB) in Plasma from mCRPC Patients Using Two Commercial NGS Assays

Scientific reports, 2019-01, Vol.9 (1), p.114-114, Article 114

2019

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In Vivo Characterization of a Novel γ-Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects

Interdisciplinary perspectives on infectious diseases, 2013, Vol.2013 (2013), p.1-14

2013

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A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit

Scientific reports, 2017-10, Vol.7 (1), p.13853-14, Article 13853

2017

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Facilitation of lin-12 -mediated signalling by sel-12 , a Caenorhabditis elegans S182 Alzheimer's disease gene

Nature (London), 1995-09, Vol.377 (6547), p.351-354

1995

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spr-2, a Suppressor of the Egg-Laying Defect Caused by Loss of sel-12 Presenilin in Caenorhabditis elegans, Is a Member of the SET Protein Subfamily

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14524-14529

2000

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Development and Validation of a Template-Independent Next-Generation Sequencing Assay for Detecting Low-Level Resistance-Associated Variants of Hepatitis C Virus

The Journal of molecular diagnostics : JMD, 2016-09, Vol.18 (5), p.643-656

2016

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In Vivo Characterization of a Novel -Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects

International journal of alzheimer's disease, 2013, Vol.2013, p.1-14

2013

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511. Treatment with Molnupiravir in the MOVe-In and MOVe-Out Clinical Trials Results in an Increase in Transition Mutations Across the SARS-CoV-2 Genome

Open forum infectious diseases, 2021-12, Vol.8 (Supplement_1), p.S357-S358

2021

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Abstract 2483: An integrated bioinformatics pipeline for profiling cancer-immune interaction from whole exome sequencing of pembrolizumab clinical samples

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2483-2483

2019

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Mutation Detection in an Antibody-Producing Chinese Hamster Ovary Cell Line by Targeted RNA Sequencing

BioMed research international, 2016-01, Vol.2016 (2016), p.1-8

2016

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Evaluation of the TruSight Oncology 500 Assay for Routine Clinical Testing of Tumor Mutational Burden and Clinical Utility for Predicting Response to Pembrolizumab

Pre-Analytical Considerations for Successful Next-Generation Sequencing (NGS): Challenges and Opportunities for Formalin-Fixed and Paraffin-Embedded Tumor Tissue (FFPE) Samples

Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice

Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation

Data Interoperability of Whole Exome Sequencing (WES) Based Mutational Burden Estimates from Different Laboratories

Perforating foreign body in the ventriculus of an umbrella cockatoo (Cacatua alba)

Proprotein convertase subtilisin/kexin type 9 (PCSK9) affects gene expression pathways beyond cholesterol metabolism in liver cells

Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab

80 Evaluation of the trusight oncology 500 assay for routine clinical testing of tumor mutational burden (TMB) and clinical utility for predicting response to pembrolizumab

Human NPC1L1 and NPC1 can functionally substitute for the ncr genes to promote reproductive development in C. elegans

Assessment of Normal and Mutant Human Presenilin Function in Caenorhabditis elegans

The Caenorhabditis elegans homolog of the putative prostate cancer susceptibility gene ELAC2, hoe-1, plays a role in germline proliferation

PS1 N- and C-Terminal Fragments Form a Complex That Functions in APP Processing and Notch Signaling

Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial

Letermovir Resistance Analysis in a Clinical Trial of Cytomegalovirus Prophylaxis for Hematopoietic Stem Cell Transplant Recipients

Measuring Tumor Mutational Burden (TMB) in Plasma from mCRPC Patients Using Two Commercial NGS Assays

In Vivo Characterization of a Novel γ-Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects

A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit

Facilitation of lin-12 -mediated signalling by sel-12 , a Caenorhabditis elegans S182 Alzheimer's disease gene

spr-2, a Suppressor of the Egg-Laying Defect Caused by Loss of sel-12 Presenilin in Caenorhabditis elegans, Is a Member of the SET Protein Subfamily

Development and Validation of a Template-Independent Next-Generation Sequencing Assay for Detecting Low-Level Resistance-Associated Variants of Hepatitis C Virus

In Vivo Characterization of a Novel -Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects

511. Treatment with Molnupiravir in the MOVe-In and MOVe-Out Clinical Trials Results in an Increase in Transition Mutations Across the SARS-CoV-2 Genome

Abstract 2483: An integrated bioinformatics pipeline for profiling cancer-immune interaction from whole exome sequencing of pembrolizumab clinical samples

Mutation Detection in an Antibody-Producing Chinese Hamster Ovary Cell Line by Targeted RNA Sequencing

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