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Hyperandrogenic origins of polycystic ovary syndrome - implications for pathophysiology and therapy

Expert review of endocrinology & metabolism, 2019-03, Vol.14 (2), p.131-143

2019

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Timing and completion of puberty in female mice depend on estrogen receptor α-signaling in kisspeptin neurons

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (52), p.22693-22698

2010

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Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits

Current pharmaceutical design, 2016-01, Vol.22 (36), p.5625-5633

2016

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Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome

Endocrinology (Philadelphia), 2020-08, Vol.161 (8), p.1

2020

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Sex differences in Hippocampal Memory and Learning following Neonatal Brain Injury: Is There a Role for Estrogen Receptor-α?

Neuroendocrinology, 2019-01, Vol.109 (3), p.249-256

2019

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Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway

Nature communications, 2023-06, Vol.14 (1), p.3801-3801, Article 3801

2023

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Brain-Endocrine Interactions: A Microvascular Route in the Mediobasal Hypothalamus

Endocrinology (Philadelphia), 2009-12, Vol.150 (12), p.5509-5519

2009

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Does the KNDy Model for the Control of Gonadotropin-Releasing Hormone Pulses Apply to Monkeys and Humans?

Seminars in reproductive medicine, 2019-03, Vol.37 (2), p.71-83

2019

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Transient prenatal androgen exposure produces metabolic syndrome in adult female rats

American journal of physiology: endocrinology and metabolism, 2008-08, Vol.295 (2), p.E262-E268

2008

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Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application

Medical sciences (Basel), 2019-11, Vol.7 (12), p.107

2019

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Accelerated Episodic Luteinizing Hormone Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca Mulatta) Exposed to Testosterone during Early-to-Mid Gestation

Neuroendocrinology, 2018-01, Vol.107 (2), p.133-146

2018

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TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury

Biology of sex differences, 2024-04, Vol.15 (1), p.30-30, Article 30

2024

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Circadian Clock Mutation Disrupts Estrous Cyclicity and Maintenance of Pregnancy

Current biology, 2004-08, Vol.14 (15), p.1367-1373

2004

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Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-Specific Deletion of Estrogen Receptor Alpha (ESR1)

Biology of reproduction, 2009-09, Vol.81 (3), p.488-496

2009

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Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors

Frontiers in bioengineering and biotechnology, 2023-07, Vol.11, p.1237613-1237613

2023

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Endocrine Antecedents of Polycystic Ovary Syndrome in Fetal and Infant Prenatally Androgenized Female Rhesus Monkeys

Biology of reproduction, 2008-07, Vol.79 (1), p.154-163

2008

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Neuroendocrine Consequences of Prenatal Androgen Exposure in the Female Rat: Absence of Luteinizing Hormone Surges, Suppression of Progesterone Receptor Gene Expression, and Acceleration of the Gonadotropin-Releasing Hormone Pulse Generator

Biology of reproduction, 2005-06, Vol.72 (6), p.1475-1483

2005

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Prenatal androgen treatment alters body composition and glucose homeostasis in male rats

Journal of endocrinology, 2011-03, Vol.208 (3), p.293-300

2011

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Vasopressin Regulation of the Proestrous Luteinizing Hormone Surge in Wild-Type and Clock Mutant Mice

Biology of reproduction, 2006-11, Vol.75 (5), p.778-784

2006

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In utero Androgen Excess: A Developmental Commonality Preceding Polycystic Ovary Syndrome?

Frontiers of hormone research, 2019, Vol.53, p.1

2019

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Positive, But Not Negative Feedback Actions of Estradiol in Adult Female Mice Require Estrogen Receptor α in Kisspeptin Neurons

Endocrinology (Philadelphia), 2015-03, Vol.156 (3), p.1111-1120

2015

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Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism

American journal of physiology: endocrinology and metabolism, 2021-08, Vol.321 (2), p.E264-E280

2021

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The NIH Somatic Cell Genome Editing program

Nature (London), 2021-04, Vol.592 (7853), p.195-204

2021

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Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice via Activation of ERα in Kisspeptin Neurons

Endocrinology (Philadelphia), 2016-04, Vol.157 (4), p.1546-1554

2016

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Brain Aromatase and the Regulation of Sexual Activity in Male Mice

Endocrinology (Philadelphia), 2020-10, Vol.161 (10), p.1

2020

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Hyperandrogenic origins of polycystic ovary syndrome - implications for pathophysiology and therapy

Timing and completion of puberty in female mice depend on estrogen receptor α-signaling in kisspeptin neurons

Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits

Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome

Sex differences in Hippocampal Memory and Learning following Neonatal Brain Injury: Is There a Role for Estrogen Receptor-α?

Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway

Brain-Endocrine Interactions: A Microvascular Route in the Mediobasal Hypothalamus

Does the KNDy Model for the Control of Gonadotropin-Releasing Hormone Pulses Apply to Monkeys and Humans?

Transient prenatal androgen exposure produces metabolic syndrome in adult female rats

Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application

Accelerated Episodic Luteinizing Hormone Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca Mulatta) Exposed to Testosterone during Early-to-Mid Gestation

TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury

Circadian Clock Mutation Disrupts Estrous Cyclicity and Maintenance of Pregnancy

Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-Specific Deletion of Estrogen Receptor Alpha (ESR1)

Striatonigral distribution of a fluorescent reporter following intracerebral delivery of genome editors

Endocrine Antecedents of Polycystic Ovary Syndrome in Fetal and Infant Prenatally Androgenized Female Rhesus Monkeys

Neuroendocrine Consequences of Prenatal Androgen Exposure in the Female Rat: Absence of Luteinizing Hormone Surges, Suppression of Progesterone Receptor Gene Expression, and Acceleration of the Gonadotropin-Releasing Hormone Pulse Generator

Prenatal androgen treatment alters body composition and glucose homeostasis in male rats

Vasopressin Regulation of the Proestrous Luteinizing Hormone Surge in Wild-Type and Clock Mutant Mice

In utero Androgen Excess: A Developmental Commonality Preceding Polycystic Ovary Syndrome?

Positive, But Not Negative Feedback Actions of Estradiol in Adult Female Mice Require Estrogen Receptor α in Kisspeptin Neurons

Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism

The NIH Somatic Cell Genome Editing program

Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice via Activation of ERα in Kisspeptin Neurons

Brain Aromatase and the Regulation of Sexual Activity in Male Mice

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