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Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines

Oncogene, 2011-04, Vol.30 (16), p.1963-1968

2011

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Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

Oncogene, 2007-08, Vol.26 (38), p.5655-5661

2007

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Navitoclax (ABT‐263) and bendamustine ± rituximab induce enhanced killing of non‐Hodgkin's lymphoma tumours in vivo

British journal of pharmacology, 2012-10, Vol.167 (4), p.881-891

2012

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The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

Science (American Association for the Advancement of Science), 1999-10, Vol.286 (5438), p.309-312

1999

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The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma

Leukemia, 2014-01, Vol.28 (1), p.210-212

2014

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RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors

Oncogene, 2006-03, Vol.25 (9), p.1340-1348

2006

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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

Cell death & disease, 2015-01, Vol.6 (1), p.e1590-e1590

2015

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Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Blood cancer journal (New York), 2015-11, Vol.5 (11), p.e368-e368

2015

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The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7

The Journal of biological chemistry, 2000-09, Vol.275 (35), p.26661-26664

2000

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Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Blood cancer journal (New York), 2016-03, Vol.6 (3), p.e403-e403

2016

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The APC11 RING-H2 finger mediates E2-dependent ubiquitination

Molecular biology of the cell, 2000-07, Vol.11 (7), p.2315-2325

2000

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Pim-1 Kinase and p100 Cooperate to Enhance c-Myb Activity

Molecular cell, 1998-10, Vol.2 (4), p.417-425

1998

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Point Mutations in v-Myb Disrupt a Cyclophilin-Catalyzed Negative Regulatory Mechanism

Molecular cell, 1998, Vol.1 (2), p.203-211

1998

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Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

Molecular biology of the cell, 2005-07, Vol.16 (7), p.3187-3199

2005

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Small interfering RNA-mediated polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals

Cancer research (Chicago, Ill.), 2005-04, Vol.65 (7), p.2698-2704

2005

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

Molecular cancer therapeutics, 2005-06, Vol.4 (6), p.977-986

2005

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Erratum: Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

Blood cancer journal (New York), 2016-03, Vol.6 (3), p.e403-e403

2016

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New opportunities in chemosensitization and radiosensitization: modulating the DNA-damage response

Expert review of anticancer therapy, 2005-04, Vol.5 (2), p.333-342

2005

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Suppressors of Bir1p (Survivin) Identify Roles for the Chromosomal Passenger Protein Pic1p (INCENP) and the Replication Initiation Factor Psf2p in Chromosome Segregation

Molecular and Cellular Biology, 2005-10, Vol.25 (20), p.9000-9015

2005

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The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis

Molecular biology of the cell, 2002-04, Vol.13 (4), p.1132-1143

2002

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From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

Nature reviews. Drug discovery, 2017-04, Vol.16 (4), p.273-284

2017

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The Significance of Donor‐Specific HLA Antibodies in Rejection and Ductopenia Development in ABO Compatible Liver Transplantation

American journal of transplantation, 2011-03, Vol.11 (3), p.500-510

2011

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Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models

Molecular cancer therapeutics, 2016-05, Vol.15 (5), p.1132-1144

2016

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5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-Mediated Apoptosis

Clinical cancer research, 2020-07, Vol.26 (13), p.3371-3383

2020

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Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines

Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

Navitoclax (ABT‐263) and bendamustine ± rituximab induce enhanced killing of non‐Hodgkin's lymphoma tumours in vivo

The Tyrosine Kinase Negative Regulator c-Cbl as a RING-Type, E2-Dependent Ubiquitin-Protein Ligase

The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma

RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7

Loss in MCL-1 function sensitizes non-Hodgkin's lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

The APC11 RING-H2 finger mediates E2-dependent ubiquitination

Pim-1 Kinase and p100 Cooperate to Enhance c-Myb Activity

Point Mutations in v-Myb Disrupt a Cyclophilin-Catalyzed Negative Regulatory Mechanism

Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference

Small interfering RNA-mediated polo-like kinase 1 depletion preferentially reduces the survival of p53-defective, oncogenic transformed cells and inhibits tumor growth in animals

Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

Erratum: Loss in MCL-1 function sensitizes non-Hodgkin’s lymphoma cell lines to the BCL-2-selective inhibitor venetoclax (ABT-199)

New opportunities in chemosensitization and radiosensitization: modulating the DNA-damage response

Suppressors of Bir1p (Survivin) Identify Roles for the Chromosomal Passenger Protein Pic1p (INCENP) and the Replication Initiation Factor Psf2p in Chromosome Segregation

The Schizosaccharomyces pombe aurora-related kinase Ark1 interacts with the inner centromere protein Pic1 and mediates chromosome segregation and cytokinesis

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

The Significance of Donor‐Specific HLA Antibodies in Rejection and Ductopenia Development in ABO Compatible Liver Transplantation

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Expression Profile of BCL-2, BCL-XL, and MCL-1 Predicts Pharmacological Response to the BCL-2 Selective Antagonist Venetoclax in Multiple Myeloma Models

5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-Mediated Apoptosis

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