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A snapshot into the transcriptomic landscape of apoptosis and ferroptosis in cancer

Cell death & disease, 2024-05, Vol.15 (5), p.371-4, Article 371

2024

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Targeted therapy and drug resistance in triple-negative breast cancer: the EGFR axis

Biochemical Society transactions, 2020-04, Vol.48 (2), p.657-665

Lev, Sima

2020

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The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice

Scientific reports, 2020-04, Vol.10 (1), p.7375-7375, Article 7375

2020

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MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells

Nature communications, 2016-12, Vol.7 (1), p.13884-13884, Article 13884

2016

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Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport

Molecular biology of the cell, 2008-09, Vol.19 (9), p.3871-3884

2008

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Non-vesicular lipid transport by lipid-transfer proteins and beyond

Nature reviews. Molecular cell biology, 2010-10, Vol.11 (10), p.739

Lev, Sima

2010

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PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop

Oncotarget, 2015-09, Vol.6 (26), p.22214-22226

2015

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Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis

Cancer research (Chicago, Ill.), 2017-01, Vol.77 (1), p.86-99

2017

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The VAP protein family: from cellular functions to motor neuron disease

Trends in cell biology, 2008-06, Vol.18 (6), p.282-290

2008

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Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing

The EMBO journal, 2009-07, Vol.28 (14), p.2006-2017

2009

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Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer

Frontiers in cell and developmental biology, 2020-01, Vol.7, p.371-371

2020

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Mammalian PITPs at the Golgi and ER-Golgi Membrane Contact Sites

Contact, 2020-01, Vol.3, p.251525642096417

2020

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Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer

PLoS computational biology, 2018-06, Vol.14 (6), p.e1006192-e1006192

2018

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Differential Regulation of Endoplasmic Reticulum Structure through VAP-Nir Protein Interaction

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5934-5944

2005

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The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis

Journal of cell science, 2014-11, Vol.127 (Pt 21), p.4740-4749

2014

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The role of the Nir/rdgB protein family in membrane trafficking and cytoskeleton remodeling

Experimental Cell Research, 2004-07, Vol.297 (1), p.1-10

Lev, Sima

2004

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Programming a Ferroptosis‐to‐Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy

Advanced science, 2024-05, Vol.11 (17), p.e2307263-n/a

2024

Volltextzugriff (PDF)

Accelerating AXL targeting for TNBC therapy

The international journal of biochemistry & cell biology, 2021-10, Vol.139, p.106057, Article 106057

2021

Volltextzugriff (PDF)

Mouse Modeling Dissecting Macrophage–Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis

Advanced science, 2022-03, Vol.9 (9), p.e2105696-n/a

2022

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Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function

Nature cell biology, 2005-03, Vol.7 (3), p.225-234

2005

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Nonvesicular lipid transfer from the endoplasmic reticulum

Cold Spring Harbor perspectives in biology, 2012-10, Vol.4 (10), p.a013300-a013300

Lev, Sima

2012

Volltextzugriff (PDF)

Tethering the assembly of SNARE complexes

Trends in cell biology, 2014-01, Vol.24 (1), p.35-43

2014

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VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity

PloS one, 2012-10, Vol.7 (10), p.e46281-e46281

2012

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Sprouty Fine-Tunes EGF Signaling through Interlinked Positive and Negative Feedback Loops

Current biology, 2003-02, Vol.13 (4), p.297-307

2003

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Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

Advanced science, 2021-02, Vol.8 (3), p.2003049-n/a

2021

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A snapshot into the transcriptomic landscape of apoptosis and ferroptosis in cancer

Targeted therapy and drug resistance in triple-negative breast cancer: the EGFR axis

The Animal Lectin Galectin-8 Promotes Cytokine Expression and Metastatic Tumor Growth in Mice

MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells

Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport

Non-vesicular lipid transport by lipid-transfer proteins and beyond

PYK2 integrates growth factor and cytokine receptors signaling and potentiates breast cancer invasion via a positive feedback loop

Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis

The VAP protein family: from cellular functions to motor neuron disease

Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing

Lipid Transfer Proteins and Membrane Contact Sites in Human Cancer

Mammalian PITPs at the Golgi and ER-Golgi Membrane Contact Sites

Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer

Differential Regulation of Endoplasmic Reticulum Structure through VAP-Nir Protein Interaction

The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis

The role of the Nir/rdgB protein family in membrane trafficking and cytoskeleton remodeling

Programming a Ferroptosis‐to‐Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy

Accelerating AXL targeting for TNBC therapy

Mouse Modeling Dissecting Macrophage–Breast Cancer Communication Uncovered Roles of PYK2 in Macrophage Recruitment and Breast Tumorigenesis

Maintenance of the diacylglycerol level in the Golgi apparatus by the Nir2 protein is critical for Golgi secretory function

Nonvesicular lipid transfer from the endoplasmic reticulum

Tethering the assembly of SNARE complexes

VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity

Sprouty Fine-Tunes EGF Signaling through Interlinked Positive and Negative Feedback Loops

Modeling Heterogeneity of Triple‐Negative Breast Cancer Uncovers a Novel Combinatorial Treatment Overcoming Primary Drug Resistance

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