UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 29

Sortiert nach

Methyl Effects on Protein–Ligand Binding

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4489-4500

2012

Volltextzugriff (PDF)

Simple Predictive Models of Passive Membrane Permeability Incorporating Size-Dependent Membrane-Water Partition

Journal of chemical information and modeling, 2016-05, Vol.56 (5), p.924-929

2016

Volltextzugriff (PDF)

Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products

Journal of the American Chemical Society, 2015-01, Vol.137 (2), p.715-721

2015

Volltextzugriff (PDF)

Testing Physical Models of Passive Membrane Permeation

Journal of chemical information and modeling, 2012-06, Vol.52 (6), p.1621-1636

2012

Volltextzugriff (PDF)

Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole

PLoS neglected tropical diseases, 2010-04, Vol.4 (4), p.e651

2010

Volltextzugriff (PDF)

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

Nature chemical biology, 2011-09, Vol.7 (11), p.810

2011

Volltextzugriff (PDF)

A Nonazole CYP51 Inhibitor Cures Chagas’ Disease in a Mouse Model of Acute Infection

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2480-2488

2010

Volltextzugriff (PDF)

Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides

Organic letters, 2015-06, Vol.17 (12), p.2928-2931

2015

Volltextzugriff (PDF)

Discovery of Potent and Orally Bioavailable Macrocyclic Peptide–Peptoid Hybrid CXCR7 Modulators

Journal of medicinal chemistry, 2017-12, Vol.60 (23), p.9653-9663

2017

Volltextzugriff (PDF)

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance()

MedChemComm, 2012-10, Vol.3 (10), p.1282-1289

2012

Volltextzugriff (PDF)

Synthesis and Evaluation of Selected Key Methyl Ether Derivatives of Vancomycin Aglycon

Journal of medicinal chemistry, 2010-10, Vol.53 (19), p.7229-7235

2010

Volltextzugriff (PDF)

Vancomycin analogs: Seeking improved binding of d-Ala- d-Ala and d-Ala- d-Lac peptides by side-chain and backbone modifications

Bioorganic & medicinal chemistry, 2009-08, Vol.17 (16), p.5874-5886

2009

Volltextzugriff (PDF)

A Self-Consistent Space-Domain Decomposition Method for QM/MM Computations of Protein Electrostatic Potentials

Journal of chemical theory and computation, 2006-01, Vol.2 (1), p.175-186

2006

Volltextzugriff (PDF)

Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

Beilstein journal of organic chemistry, 2013-01, Vol.9 (1), p.15-25

2013

Volltextzugriff (PDF)

Vancomycin resistance: Modeling backbone variants with d-Ala- d-Ala and d-Ala- d-Lac peptides

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1236-1239

2009

Volltextzugriff (PDF)

Abstract 5379: Macrocycles inhibiting RxL-mediated binding of substrates to Cyclin A are synthetic lethal in Rb mutated small cell lung carcinoma (SCLC)

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.5379-5379

2022

Volltextzugriff (PDF)

Abstract 1560: Orally bioavailable macrocycles that target cyclins A and B RxL motifs cause tumor regression in xenograft models and in vitro show activity across multiple cancer types

Cancer research (Chicago, Ill.), 2023-04, Vol.83 (7_Supplement), p.1560-1560

2023

Volltextzugriff (PDF)

CHAPTER 10 - Optimizing the Permeability and Oral Bioavailability of Macrocycles

Macrocycles in drug discovery, 2015, p.367-397

2015

Volltextzugriff (PDF)

Advances in computer -aided drug design with applications to glycopeptide antibiotics

Leung, Siegfried Sik Fai

2009

Volltextzugriff (PDF)

Optimizing the Permeability and Oral Bioavailability of Macrocycles

Macrocycles in Drug Discovery, 2014

Levin, Jeremy

2014

Volltextzugriff (PDF)

Systematic investigation of the link between enzyme catalysis and cold adaptation

eLife, 2022-01, Vol.11

2022

Volltextzugriff (PDF)

Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort Study

Circulation (New York, N.Y.), 2024-01, Vol.149 (2), p.124

2024

Volltextzugriff (PDF)

1 – 25 von 29

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(25)
Mit Volltextzugriff
(26)

Publikationsform

Sprache

Englisch
(29)
Japanisch
(8)

Erscheinungsjahr

n.n

Thema

Science & Technology
(22)
Life Sciences & Biomedicine
(17)
Pharmacology & Pharmacy
(10)
Chemistry
(9)
Chemistry, Medicinal
(9)
Physical Sciences
(9)
Humans
(7)
Models, Molecular
(7)
Animals
(6)
Structure-Activity Relationship
(6)
Biological And Medical Sciences
(5)
Medical Sciences
(5)
Thermodynamics
(5)
Chemistry, Organic
(4)
Female
(4)
Male
(4)
Peptides - Chemistry
(4)
Pharmacology. Drug Treatments
(4)
Anti-Bacterial Agents - Pharmacology
(3)
Biochemistry & Molecular Biology
(3)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Methyl Effects on Protein–Ligand Binding

Simple Predictive Models of Passive Membrane Permeability Incorporating Size-Dependent Membrane-Water Partition

Cell-Permeable Cyclic Peptides from Synthetic Libraries Inspired by Natural Products

Testing Physical Models of Passive Membrane Permeation

Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole

On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffolds

A Nonazole CYP51 Inhibitor Cures Chagas’ Disease in a Mouse Model of Acute Infection

Peptide to Peptoid Substitutions Increase Cell Permeability in Cyclic Hexapeptides

Discovery of Potent and Orally Bioavailable Macrocyclic Peptide–Peptoid Hybrid CXCR7 Modulators

Optimizing PK properties of cyclic peptides: the effect of side chain substitutions on permeability and clearance()

Synthesis and Evaluation of Selected Key Methyl Ether Derivatives of Vancomycin Aglycon

Vancomycin analogs: Seeking improved binding of d-Ala- d-Ala and d-Ala- d-Lac peptides by side-chain and backbone modifications

A Self-Consistent Space-Domain Decomposition Method for QM/MM Computations of Protein Electrostatic Potentials

Chemical-biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

Vancomycin resistance: Modeling backbone variants with d-Ala- d-Ala and d-Ala- d-Lac peptides

Abstract 5379: Macrocycles inhibiting RxL-mediated binding of substrates to Cyclin A are synthetic lethal in Rb mutated small cell lung carcinoma (SCLC)

Abstract 1560: Orally bioavailable macrocycles that target cyclins A and B RxL motifs cause tumor regression in xenograft models and in vitro show activity across multiple cancer types

CHAPTER 10 - Optimizing the Permeability and Oral Bioavailability of Macrocycles

Advances in computer -aided drug design with applications to glycopeptide antibiotics

Optimizing the Permeability and Oral Bioavailability of Macrocycles

Systematic investigation of the link between enzyme catalysis and cold adaptation

Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort Study

West African monsoon decadal variability and surface-related forcings: second West African Monsoon Modeling and Evaluation Project Experiment (WAMME II)

Developing drugs for treatment of atopic dermatitis in children (≥3 months to <18 years of age): Draft guidance for industry

Suchergebnisse filtern