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The Multiple Challenges of Handling Scientific Integrity in the Swiss Higher Education System

Chimia, 2024-09, Vol.78 (9), p.610-612

Leumann, Christian J

2024

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Enzymatic synthesis of biphenyl-DNA oligonucleotides

Bioorganic & medicinal chemistry, 2020-06, Vol.28 (11), p.115487-115487, Article 115487

2020

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7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy

Nucleic acids research, 2021-12, Vol.49 (21), p.12089-12105

2021

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Alternative DNA base-pairs: from efforts to expand the genetic code to potential material applications

Chemical Society reviews, 2011-01, Vol.40 (12), p.5669-5679

2011

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Probing the Backbone Topology of DNA: Synthesis and Properties of 7′,5′‐Bicyclo‐DNA

Chemistry : a European journal, 2017-06, Vol.23 (33), p.7953-7968

2017

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Enzymatic Synthesis of 7′,5′‐Bicyclo‐DNA Oligonucleotides

Chemistry, an Asian journal, 2017-06, Vol.12 (12), p.1347-1352

2017

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Synthesis and Biochemical Characterization of Tricyclothymidine Triphosphate (tc-TTP)

Chembiochem : a European journal of chemical biology, 2014-09, Vol.15 (13), p.1901-1904

2014

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Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers

Nature Medicine, 2015-03, Vol.21 (3), p.270-275

2015

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Compatibility of 5-ethynyl-2′F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers

Organic & biomolecular chemistry, 2019-09, Vol.17 (35), p.8083-8087

2019

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The effect of RNA base lesions on mRNA translation

Nucleic acids research, 2015-05, Vol.43 (9), p.4713-4720

2015

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A 6′-Fluoro-Substituent in Bicyclo-DNA Increases Affinity to Complementary RNA Presumably by CF–HC Pseudohydrogen Bonds

Journal of organic chemistry, 2014-02, Vol.79 (3), p.1271-1279

2014

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Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates

Chemistry : a European journal, 2017-02, Vol.23 (9), p.2022-2025

2017

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2′-Fluorination of Tricyclo-DNA Controls Furanose Conformation and Increases RNA Affinity

Organic letters, 2015-04, Vol.17 (8), p.1950-1953

2015

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6'-Fluoro[4.3.0]bicyclo nucleic acid: synthesis, biophysical properties and molecular dynamics simulations

Beilstein journal of organic chemistry, 2018-12, Vol.14 (1), p.3088-3097

2018

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Back Cover: Probing the Backbone Topology of DNA: Synthesis and Properties of 7′,5′‐Bicyclo‐DNA (Chem. Eur. J. 33/2017)

Chemistry : a European journal, 2017-06, Vol.23 (33), p.8100-8100

2017

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2'β-Fluoro-Tricyclo Nucleic Acids (2'F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation

Chemistry : a European journal, 2017-08, Vol.23 (43), p.10310-10318

2017

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2‑Pyrenyl-DNA: Synthesis, Pairing, and Fluorescence Properties

Organic letters, 2012-10, Vol.14 (20), p.5176-5179

2012

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Corrigendum: Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates

Chemistry : a European journal, 2017-04, Vol.23 (20), p.4944-4944

2017

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DNA Analogues: From Supramolecular Principles to Biological Properties

Bioorganic & Medicinal Chemistry, 2002-04, Vol.10 (4), p.841-854

Leumann, Christian J.

2002

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Synthesis and Properties of 6′-Fluoro-tricyclo-DNA

Journal of organic chemistry, 2015-04, Vol.80 (7), p.3556-3565

2015

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TricycloDNA-modified oligo-2′-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues—a comparative study of oligonucleotide length, design and chemistry

Nucleic acids research, 2012-07, Vol.40 (13), p.6135-6143

2012

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Base Pairing and Miscoding Properties of 1,N6‑Ethenoadenine- and 3,N4‑Ethenocytosine-Containing RNA Oligonucleotides

Biochemistry (Easton), 2013-03, Vol.52 (11), p.1990-1997

2013

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Base pairing and miscoding properties of 1,N(6)-ethenoadenine- and 3,N(4)-ethenocytosine-containing RNA oligonucleotides

Biochemistry (Easton), 2013-03, Vol.52 (11), p.1990-1997

2013

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Stable Cyclohexyl-Phenyl Recognition in the Center of a DNA Duplex

Angewandte Chemie (International ed.), 2009-05, Vol.48 (21), p.3810-3813

2009

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NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance

Nucleic acids research, 2019-05, Vol.47 (9), p.4872-4882

2019

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The Multiple Challenges of Handling Scientific Integrity in the Swiss Higher Education System

Enzymatic synthesis of biphenyl-DNA oligonucleotides

7',5'-alpha-bicyclo-DNA: new chemistry for oligonucleotide exon splicing modulation therapy

Alternative DNA base-pairs: from efforts to expand the genetic code to potential material applications

Probing the Backbone Topology of DNA: Synthesis and Properties of 7′,5′‐Bicyclo‐DNA

Enzymatic Synthesis of 7′,5′‐Bicyclo‐DNA Oligonucleotides

Synthesis and Biochemical Characterization of Tricyclothymidine Triphosphate (tc-TTP)

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers

Compatibility of 5-ethynyl-2′F-ANA UTP with in vitro selection for the generation of base-modified, nuclease resistant aptamers

The effect of RNA base lesions on mRNA translation

A 6′-Fluoro-Substituent in Bicyclo-DNA Increases Affinity to Complementary RNA Presumably by CF–HC Pseudohydrogen Bonds

Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates

2′-Fluorination of Tricyclo-DNA Controls Furanose Conformation and Increases RNA Affinity

6'-Fluoro[4.3.0]bicyclo nucleic acid: synthesis, biophysical properties and molecular dynamics simulations

Back Cover: Probing the Backbone Topology of DNA: Synthesis and Properties of 7′,5′‐Bicyclo‐DNA (Chem. Eur. J. 33/2017)

2'β-Fluoro-Tricyclo Nucleic Acids (2'F-tc-ANA): Thermal Duplex Stability, Structural Studies, and RNase H Activation

2‑Pyrenyl-DNA: Synthesis, Pairing, and Fluorescence Properties

Corrigendum: Modulation of Excess Electron Transfer through LUMO Gradients in DNA Containing Phenanthrenyl Base Surrogates

DNA Analogues: From Supramolecular Principles to Biological Properties

Synthesis and Properties of 6′-Fluoro-tricyclo-DNA

TricycloDNA-modified oligo-2′-deoxyribonucleotides reduce scavenger receptor B1 mRNA in hepatic and extra-hepatic tissues—a comparative study of oligonucleotide length, design and chemistry

Base Pairing and Miscoding Properties of 1,N6‑Ethenoadenine- and 3,N4‑Ethenocytosine-Containing RNA Oligonucleotides

Base pairing and miscoding properties of 1,N(6)-ethenoadenine- and 3,N(4)-ethenocytosine-containing RNA oligonucleotides

Stable Cyclohexyl-Phenyl Recognition in the Center of a DNA Duplex

NMR solution structure of tricyclo-DNA containing duplexes: insight into enhanced thermal stability and nuclease resistance

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