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Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

Leukemia, 2018-02, Vol.32 (2), p.303-312

2018

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Cell death and the mitochondria: therapeutic targeting of the BCL‐2 family‐driven pathway

British journal of pharmacology, 2014-04, Vol.171 (8), p.1973-1987

2014

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HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death

Cell death & disease, 2016-01, Vol.7 (1), p.e2051-e2051

2016

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Effects of modulators of Ca(2+)-activated, intermediate-conductance potassium channels on motility of the rat small intestine, in vivo

Neurogastroenterology and motility, 2007-05, Vol.19 (5), p.383-389

2007

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Dissecting the RIPK3/MLKL necroptotic molecular switch

Acta crystallographica. Section A, Foundations and advances, 2023-08, Vol.79 (a2), p.C842-C842

2023

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MA27.09 Dual Inhibition of BCL-XL and MCL-1 is Required to Induce Tumour Regression in Lung Squamous Cell Carcinomas Sensitive to FGFR Inhibition

Journal of thoracic oncology, 2018-10, Vol.13 (10), p.S457-S457

2018

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Advances in the Negishi Coupling

Australian journal of chemistry, 2004, Vol.57 (1), p.107

Lessene, Guillaume

2004

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A Concise Total Synthesis of Naamidine A

Organic letters, 2006-02, Vol.8 (3), p.419-421

2006

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Effects of modulators of Ca2+‐activated, intermediate‐conductance potassium channels on motility of the rat small intestine, in vivo

Neurogastroenterology and motility, 2007-05, Vol.19 (5), p.383-389

2007

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Diazonamide Synthesis Studies: Use of Negishi Coupling to Fashion Diazonamide-Related Biaryls with Defined Axial Chirality

Organic letters, 2002-10, Vol.4 (20), p.3525-3528

2002

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The Tyr-Kinase Inhibitor AG879, that Blocks the ETK-PAK1 Interaction, Suppresses the RAS-induced PAK1 Activation and Malignant Transformation

Cancer biology & therapy, 2004-01, Vol.3 (1), p.96-101

2004

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Selective electrochemical synthesis and reactivity of functional benzylic fluorosilylsynthons

Journal of fluorine chemistry, 2001-02, Vol.107 (2), p.301-310

2001

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Effects of modulators of Ca super(2+)-activated, intermediate-conductance potassium channels on motility of the rat small intestine, in vivo

Neurogastroenterology and motility, 2007-05, Vol.19 (5), p.383-389

2007

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Effects of modulators of Ca 2+ ‐activated, intermediate‐conductance potassium channels on motility of the rat small intestine, in vivo

Neurogastroenterology and motility, 2007-05, Vol.19 (5), p.383-389

2007

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Towards the electroreduction of very weak acids

Journal of electroanalytical chemistry (Lausanne, Switzerland), 2000-08, Vol.490 (1), p.79-84

2000

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Magnesium bis(diisopropylamide), a useful reagent for regio- and stereoselective synthesis of kinetic silyl enol ethers

Tetrahedron letters, 1999-05, Vol.40 (21), p.4037-4040

1999

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ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types

Clinical cancer research, 2017-09, Vol.23 (18), p.5573-5584

2017

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Removal of BFL-1 sensitises some melanoma cells to killing by BH3 mimetic drugs

Cell death & disease, 2022-04, Vol.13 (4), p.301-301, Article 301

2022

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Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape

Nature communications, 2024-07, Vol.15 (1), p.6219-18, Article 6219

2024

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The Impact of Molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Poly l-Lysine Dendrimers

Molecular pharmaceutics, 2008-05, Vol.5 (3), p.449-463

2008

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Structure-guided design of a selective BCL-XL inhibitor

Nature chemical biology, 2013-06, Vol.9 (6), p.390-397

2013

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BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

Cell death and differentiation, 2022-07, Vol.29 (7), p.1335-1348

2022

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Enhancing venetoclax activity in acute myeloid leukemia by co-targeting MCL1

Cell death and the mitochondria: therapeutic targeting of the BCL‐2 family‐driven pathway

HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death

Effects of modulators of Ca(2+)-activated, intermediate-conductance potassium channels on motility of the rat small intestine, in vivo

Dissecting the RIPK3/MLKL necroptotic molecular switch

MA27.09 Dual Inhibition of BCL-XL and MCL-1 is Required to Induce Tumour Regression in Lung Squamous Cell Carcinomas Sensitive to FGFR Inhibition

Advances in the Negishi Coupling

A Concise Total Synthesis of Naamidine A

Effects of modulators of Ca2+‐activated, intermediate‐conductance potassium channels on motility of the rat small intestine, in vivo

Diazonamide Synthesis Studies: Use of Negishi Coupling to Fashion Diazonamide-Related Biaryls with Defined Axial Chirality

The Tyr-Kinase Inhibitor AG879, that Blocks the ETK-PAK1 Interaction, Suppresses the RAS-induced PAK1 Activation and Malignant Transformation

Selective electrochemical synthesis and reactivity of functional benzylic fluorosilylsynthons

Effects of modulators of Ca super(2+)-activated, intermediate-conductance potassium channels on motility of the rat small intestine, in vivo

Effects of modulators of Ca 2+ ‐activated, intermediate‐conductance potassium channels on motility of the rat small intestine, in vivo

Towards the electroreduction of very weak acids

Magnesium bis(diisopropylamide), a useful reagent for regio- and stereoselective synthesis of kinetic silyl enol ethers

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

ATF3 Repression of BCL-XL Determines Apoptotic Sensitivity to HDAC Inhibitors across Tumor Types

Removal of BFL-1 sensitises some melanoma cells to killing by BH3 mimetic drugs

Mutational profiling of SARS-CoV-2 papain-like protease reveals requirements for function, structure, and drug escape

The Impact of Molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Poly l-Lysine Dendrimers

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

Structure-guided design of a selective BCL-XL inhibitor

BH3 mimetic drugs cooperate with Temozolomide, JQ1 and inducers of ferroptosis in killing glioblastoma multiforme cells

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