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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

Molecular cell, 2013-08, Vol.51 (4), p.409-422

2013

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The redox regulation of PI 3-kinase-dependent signaling

Antioxidants & redox signaling, 2006-09, Vol.8 (9-10), p.1765-1774

Leslie, Nick R

2006

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PTEN function: how normal cells control it and tumour cells lose it

Biochemical journal, 2004-08, Vol.382 (Pt 1), p.1-11

2004

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The PTEN protein: cellular localization and post-translational regulation

Biochemical Society transactions, 2016-02, Vol.44 (1), p.273-278

2016

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Mutant PTEN in Cancer: Worse Than Nothing

Cell, 2014-04, Vol.157 (3), p.527-529

2014

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The TSC1-2 Tumor Suppressor Controls Insulin-PI3K Signaling via Regulation of IRS Proteins

The Journal of cell biology, 2004-07, Vol.166 (2), p.213-223

2004

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Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Molecular and Cellular Biology, 2013-11, Vol.33 (21), p.4152-4165

2013

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Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake

The Journal of biological chemistry, 2008-10, Vol.283 (41), p.27653-27667

2008

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Hypomorphic Mutation of PDK1 Suppresses Tumorigenesis in PTEN+/− Mice

Current biology, 2005-10, Vol.15 (20), p.1839-1846

2005

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Non-genomic loss of PTEN function in cancer: not in my genes

Trends in pharmacological sciences (Regular ed.), 2011-03, Vol.32 (3), p.131-140

2011

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PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate

Biomolecules (Basel, Switzerland), 2022-10, Vol.12 (10), p.1511

2022

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Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

The Journal of biological chemistry, 2010-04, Vol.285 (17), p.12620-12628

2010

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GSK3 and its interactions with the PI3K/AKT/mTOR signalling network

Advances in biological regulation, 2017-08, Vol.65, p.5-15

2017

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C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy

Molecular and Cellular Biology, 2013-04, Vol.33 (8), p.1608-1620

2013

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Importin-11 keeps PTEN safe from harm

The Journal of cell biology, 2017-03, Vol.216 (3), p.539-541

Leslie, Nick R

2017

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Proteomic and yeast 2-hybrid screens to identify PTEN binding partners

Advances in biological regulation, 2024-01, Vol.91, p.100989, Article 100989

2024

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PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

The Journal of clinical investigation, 2008-11, Vol.118 (11), p.3762-3774

2008

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PTEN: an intercellular peacekeeper?

Science signaling, 2012-11, Vol.5 (250), p.pe50

Leslie, Nick R

2012

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PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity

Science signaling, 2012-02, Vol.5 (213), p.ra18

2012

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Redox regulation of PI 3-kinase signalling via inactivation of PTEN

The EMBO journal, 2003-10, Vol.22 (20), p.5501-5510

2003

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Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

Biochemical journal, 2004-02, Vol.377 (Pt 3), p.653-663

2004

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PTEN: The down side of PI 3-kinase signalling

Cellular Signalling, 2002-04, Vol.14 (4), p.285-295

2002

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Localization of agonist-sensitive PtdIns(3,4,5)P₃ reveals a nuclear pool that is insensitive to PTEN expression

Journal of cell science, 2006-12, Vol.119 (24), p.5160-5168

2006

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P-REX2a driving tumorigenesis by PTEN inhibition

Science signaling, 2009-10, Vol.2 (94), p.pe68

Leslie, Nick R

2009

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Identification of a PTEN mutation with reduced protein stability, phosphatase activity, and nuclear localization in Hong Kong patients with autistic features, neurodevelopmental delays, and macrocephaly

Autism research, 2018-08, Vol.11 (8), p.1098-1109

2018

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MC1R Is a Potent Regulator of PTEN after UV Exposure in Melanocytes

The redox regulation of PI 3-kinase-dependent signaling

PTEN function: how normal cells control it and tumour cells lose it

The PTEN protein: cellular localization and post-translational regulation

Mutant PTEN in Cancer: Worse Than Nothing

The TSC1-2 Tumor Suppressor Controls Insulin-PI3K Signaling via Regulation of IRS Proteins

Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling

Use of Akt Inhibitor and a Drug-resistant Mutant Validates a Critical Role for Protein Kinase B/Akt in the Insulin-dependent Regulation of Glucose and System A Amino Acid Uptake

Hypomorphic Mutation of PDK1 Suppresses Tumorigenesis in PTEN+/− Mice

Non-genomic loss of PTEN function in cancer: not in my genes

PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate

Ubiquitination of PTEN (Phosphatase and Tensin Homolog) Inhibits Phosphatase Activity and Is Enhanced by Membrane Targeting and Hyperosmotic Stress

GSK3 and its interactions with the PI3K/AKT/mTOR signalling network

C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy

Importin-11 keeps PTEN safe from harm

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners

PTEN posttranslational inactivation and hyperactivation of the PI3K/Akt pathway sustain primary T cell leukemia viability

PTEN: an intercellular peacekeeper?

PTEN protein phosphatase activity correlates with control of gene expression and invasion, a tumor-suppressing phenotype, but not with AKT activity

Redox regulation of PI 3-kinase signalling via inactivation of PTEN

Detection of novel intracellular agonist responsive pools of phosphatidylinositol 3,4-bisphosphate using the TAPP1 pleckstrin homology domain in immunoelectron microscopy

PTEN: The down side of PI 3-kinase signalling

Localization of agonist-sensitive PtdIns(3,4,5)P₃ reveals a nuclear pool that is insensitive to PTEN expression

P-REX2a driving tumorigenesis by PTEN inhibition

Identification of a PTEN mutation with reduced protein stability, phosphatase activity, and nuclear localization in Hong Kong patients with autistic features, neurodevelopmental delays, and macrocephaly

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