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Withaferin A targets heat shock protein 90 in pancreatic cancer cells

Biochemical pharmacology, 2010-02, Vol.79 (4), p.542-551

2010

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An epigenetic modifier induces production of (10′S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla

Bioorganic & medicinal chemistry, 2017-03, Vol.25 (6), p.1860-1866

2017

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Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest

Translational oncology, 2022-01, Vol.15 (1), p.101259-101259, Article 101259

2022

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Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain

Neurobiology of pain, 2023-01, Vol.13, p.100116-100116, Article 100116

2023

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A novel needle-free method of lidocaine administration during standing castration of Holstein bulls

JDS communications, 2024-03, Vol.5 (2), p.150-154

2024

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Corrigendum to “Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest”

Translational oncology, 2022-07, Vol.21, p.101446-101446, Article 101446

2022

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Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana

Fungal genetics and biology, 2009-05, Vol.46 (5), p.353-364

2009

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A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7917-7923

2006

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Biomimetic conversion of (−)-fusoxypyridone and (−)-oxysporidinone to (−)-sambutoxin: Further evidence for the structure of the tricyclic pyridone alkaloid, (−)-fusoxypyridone

Bioorganic & medicinal chemistry letters, 2011-04, Vol.21 (8), p.2327-2329

2011

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PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

PLoS pathogens, 2010-08, Vol.6 (8), p.e1001069-e1001069

2010

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Tricinonoic acid and tricindiol, two new irregular sesquiterpenes from an endophytic strain of Fusarium tricinctum

Natural product research, 2010-03, Vol.24 (4), p.349-356

2010

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Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation

Cell chemical biology, 2019-10, Vol.26 (10), p.1427-1435.e5

2019

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The anticancer activity of the fungal metabolite terrecyclic acid A is associated with modulation of multiple cellular stress response pathways

Molecular cancer therapeutics, 2005-10, Vol.4 (10), p.1569-1576

2005

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Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels

Pain (Amsterdam), 2019-01, Vol.160 (1), p.117-135

2019

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Rational Reprogramming of O‑Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds

Journal of the American Chemical Society, 2019-03, Vol.141 (10), p.4355-4364

2019

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Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryi

Bioorganic & medicinal chemistry, 2014-11, Vol.22 (21), p.6112-6116

2014

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Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

Cancer research (Chicago, Ill.), 2021-06, Vol.81 (12), p.3374-3386

2021

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Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica

Phytochemistry (Oxford), 2018-08, Vol.152, p.174-181

2018

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An epigenetic modifier induces production of 3-(4-oxopyrano)-chromen-2-ones in Aspergillus sp. AST0006, an endophytic fungus of Astragalus lentiginosus

Tetrahedron, 2020-10, Vol.76 (43), p.131525, Article 131525

2020

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Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis

ACS chemical biology, 2012-02, Vol.7 (2), p.340-349

2012

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Microbial transformation of some triterpenoids of Guayule resin by Chaetomium sp

Phytochemistry letters, 2023-06, Vol.55, p.124-130

2023

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Unusual withanolides from aeroponically grown Withania somnifera

Phytochemistry (Oxford), 2011-04, Vol.72 (6), p.518-522

2011

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Rhizosphere Fungus Enhances Arabidopsis Thermotolerance through Production of an HSP90 Inhibitor

Plant physiology (Bethesda), 2007-09, Vol.145 (1), p.174-182

2007

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Discovery of diminazene as a dual inhibitor of SARS-CoV-2 human host proteases TMPRSS2 and furin using cell-based assays

Current research in chemical biology, 2022, Vol.2, p.100023-100023, Article 100023

2022

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Withanolide D Enhances Radiosensitivity of Human Cancer Cells by Inhibiting DNA Damage Non-homologous End Joining Repair Pathway

Frontiers in oncology, 2020-01, Vol.9, p.1468-1468

2020

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Withaferin A targets heat shock protein 90 in pancreatic cancer cells

An epigenetic modifier induces production of (10′S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla

Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest

Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain

A novel needle-free method of lidocaine administration during standing castration of Holstein bulls

Corrigendum to “Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest”

Biosynthesis of the cyclooligomer depsipeptide bassianolide, an insecticidal virulence factor of Beauveria bassiana

A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity

Biomimetic conversion of (−)-fusoxypyridone and (−)-oxysporidinone to (−)-sambutoxin: Further evidence for the structure of the tricyclic pyridone alkaloid, (−)-fusoxypyridone

PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90

Tricinonoic acid and tricindiol, two new irregular sesquiterpenes from an endophytic strain of Fusarium tricinctum

Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation

The anticancer activity of the fungal metabolite terrecyclic acid A is associated with modulation of multiple cellular stress response pathways

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels

Rational Reprogramming of O‑Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds

Altertoxins with potent anti-HIV activity from Alternaria tenuissima QUE1Se, a fungal endophyte of Quercus emoryi

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica

An epigenetic modifier induces production of 3-(4-oxopyrano)-chromen-2-ones in Aspergillus sp. AST0006, an endophytic fungus of Astragalus lentiginosus

Using the Heat-Shock Response To Discover Anticancer Compounds that Target Protein Homeostasis

Microbial transformation of some triterpenoids of Guayule resin by Chaetomium sp

Unusual withanolides from aeroponically grown Withania somnifera

Rhizosphere Fungus Enhances Arabidopsis Thermotolerance through Production of an HSP90 Inhibitor

Discovery of diminazene as a dual inhibitor of SARS-CoV-2 human host proteases TMPRSS2 and furin using cell-based assays

Withanolide D Enhances Radiosensitivity of Human Cancer Cells by Inhibiting DNA Damage Non-homologous End Joining Repair Pathway

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