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Novel and Potent Adenosine 3',5'-Cyclic Phosphate Phosphodiesterase III Inhibitors: Thiazolo[4,5-b][1,6]naphthyridin-2-ones

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2546-2550

1995

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Cardiotonic Activity of Amrinone–Win 40680 [5-Amino-3,4f-bipyridin-6(lH)-one]

Circulation research, 1979-11, Vol.45 (5), p.666-677

1979

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Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor

The Journal of pharmacology and experimental therapeutics, 1994-12, Vol.271 (3), p.1143

1994

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Novel cAMP PDE III inhibitors: imidazo[4,5-b]pyridin-2(3H)-ones and thiazolo[4,5-b]pyridin-2(3H)-ones and their analogs

Journal of medicinal chemistry, 1994-01, Vol.37 (2), p.248-254

1994

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In vitro and in vivo activities of a new quinolone, WIN 57273, possessing potent activity against gram-positive bacteria

Antimicrobial Agents and Chemotherapy, 1990-04, Vol.34 (4), p.568-575

1990

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Novel cAMP PDE III inhibitors: 1,6-naphthyridin-2(1H)-ones

Journal of medicinal chemistry, 1992-12, Vol.35 (26), p.4858-4865

1992

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Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and related derivatives

Journal of medicinal chemistry, 1993-09, Vol.36 (19), p.2801-2809

1993

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Synthesis of 7-azaindole and 7-azaoxindole derivatives through a palladium-catalyzed cross-coupling reaction

Journal of organic chemistry, 1992-12, Vol.57 (25), p.6995-6998

1992

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Synthesis and Antibacterial Activity of Some Novel 1-Substituted 1,4-Dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic Acids. Potent Antistaphylococcal Agents

Journal of medicinal chemistry, 1995-07, Vol.38 (14), p.2531-2540

1995

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Synthesis of 3-Methyl and 7-Methyl Regio Isomers of Medorinone

Synthesis (Stuttgart), 1991, Vol.1991 (10), p.894-896

1991

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A Convenient Synthesis of 8-Alkyl- and 8-Alkylthio-2-(4-pyridyl)adenines

Synthesis (Stuttgart), 1991, Vol.1991 (3), p.211-213

1991

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Species-Dependent Pharmacodynamic Effects of the Selective Low Km Cyclic AMP Phosphodiesterase III Inhibitors WIN 58993 and WIN 62005

Journal of cardiovascular pharmacology, 1995-01, Vol.25 (1), p.14-21

1995

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Synthesis of analogs of amrinone: 4-(3,4-Disubstitutedphenyl)pyridines and derivatives thereof

Journal of heterocyclic chemistry, 1991-06, Vol.28 (4), p.933-937

1991

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An efficient and novel synthesis of fused thiazol-2(3H)-ones

Heterocycles, 1993, Vol.36 (1), p.133-144

1993

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A convenient synthesis of 3-(4-pyridinyl)quinolines

Journal of heterocyclic chemistry, 1991-08, Vol.28 (5), p.1453-1454

1991

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Pharmacologic and pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 63291 and WIN 62582

Journal of cardiovascular pharmacology, 1994-09, Vol.24 (3), p.403-410

1994

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Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid

The Journal of pharmacology and experimental therapeutics, 1967-11, Vol.158 (2), p.286

1967

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Absorption, excretion, and metabolism of a new antibacterial agent, nalidixic acid

Toxicology and applied pharmacology, 1964-05, Vol.6 (3), p.292-309

1964

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Relationship of structure of bridged (2,6-dimethyl-4-pyridinyl)quinolones to mammalian topoisomerase II inhibition

Bioorganic & medicinal chemistry letters, 1993-08, Vol.3 (8), p.1711-1716

1993

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Novel rearrangement of N'―alkyl-N-alkyl-N-[2-(4.pyridinyl)-4-pyrimidinyl]ureas with sodium hydride

Heterocycles, 1984, Vol.22 (5), p.1133-1135

1984

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Intramolecular Hydrogen Bonding in 7-Chloro-4-diethylaminoethylaminoquinoline

Journal of the American Chemical Society, 1959-06, Vol.81 (11), p.2897-2898

1959

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Novel orally active inhibitors of passive cutaneous anaphylaxis in rats: N-[2-(4-Pyridinyl)-4-pyrimidinyl] ureas and dialkyl [[[2-(4-pyridinyl)-4-pyrimidinyl]amino]methylene]malonates

Journal of medicinal chemistry, 1982-07, Vol.25 (7), p.837-842

1982

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Synthesis of aza of amrinone

Heterocycles, 1990, Vol.31 (12), p.2163-2172

1990

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A facile and novel synthesis of 1,6-naphtyridin-2(1H)-ones

Journal of heterocyclic chemistry, 1990, Vol.27 (7), p.2085-2091

1990

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1,8-Naphthyridine Derivatives. A New Class of Chemotherapeutic Agents

Journal of Medicinal and Pharmaceutical Chemistry, 1962-09, Vol.5 (5), p.1063-1065

1962

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Novel and Potent Adenosine 3',5'-Cyclic Phosphate Phosphodiesterase III Inhibitors: Thiazolo[4,5-b][1,6]naphthyridin-2-ones

Cardiotonic Activity of Amrinone–Win 40680 [5-Amino-3,4f-bipyridin-6(lH)-one]

Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor

Novel cAMP PDE III inhibitors: imidazo[4,5-b]pyridin-2(3H)-ones and thiazolo[4,5-b]pyridin-2(3H)-ones and their analogs

In vitro and in vivo activities of a new quinolone, WIN 57273, possessing potent activity against gram-positive bacteria

Novel cAMP PDE III inhibitors: 1,6-naphthyridin-2(1H)-ones

Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8-difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and related derivatives

Synthesis of 7-azaindole and 7-azaoxindole derivatives through a palladium-catalyzed cross-coupling reaction

Synthesis and Antibacterial Activity of Some Novel 1-Substituted 1,4-Dihydro-4-oxo-7-pyridinyl-3-quinolinecarboxylic Acids. Potent Antistaphylococcal Agents

Synthesis of 3-Methyl and 7-Methyl Regio Isomers of Medorinone

A Convenient Synthesis of 8-Alkyl- and 8-Alkylthio-2-(4-pyridyl)adenines

Species-Dependent Pharmacodynamic Effects of the Selective Low Km Cyclic AMP Phosphodiesterase III Inhibitors WIN 58993 and WIN 62005

Synthesis of analogs of amrinone: 4-(3,4-Disubstitutedphenyl)pyridines and derivatives thereof

An efficient and novel synthesis of fused thiazol-2(3H)-ones

A convenient synthesis of 3-(4-pyridinyl)quinolines

Pharmacologic and pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 63291 and WIN 62582

Pharmacologic studies with 7-benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid

Absorption, excretion, and metabolism of a new antibacterial agent, nalidixic acid

Relationship of structure of bridged (2,6-dimethyl-4-pyridinyl)quinolones to mammalian topoisomerase II inhibition

Novel rearrangement of N'―alkyl-N-alkyl-N-[2-(4.pyridinyl)-4-pyrimidinyl]ureas with sodium hydride

Intramolecular Hydrogen Bonding in 7-Chloro-4-diethylaminoethylaminoquinoline

Novel orally active inhibitors of passive cutaneous anaphylaxis in rats: N-[2-(4-Pyridinyl)-4-pyrimidinyl] ureas and dialkyl [[[2-(4-pyridinyl)-4-pyrimidinyl]amino]methylene]malonates

Synthesis of aza of amrinone

A facile and novel synthesis of 1,6-naphtyridin-2(1H)-ones

1,8-Naphthyridine Derivatives. A New Class of Chemotherapeutic Agents

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