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Bendamustine (Treanda) Displays a Distinct Pattern of Cytotoxicity and Unique Mechanistic Features Compared with Other Alkylating Agents

Clinical cancer research, 2008-01, Vol.14 (1), p.309-317

2008

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Bendamustine: Rescue of an Effective Antineoplastic Agent From the Mid-Twentieth Century

Seminars in hematology, 2011-04, Vol.48, p.S4-S11

Leoni, Lorenzo M

2011

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Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I

PloS one, 2024-05, Vol.19 (5), p.e0303789-e0303789

2024

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Activation of the Wnt Signaling Pathway in Chronic Lymphocytic Leukemia

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (9), p.3118-3123

2004

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Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity

Seminars in hematology, 2011-04, Vol.48, p.S12-S23

2011

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Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria

Blood, 2000-11, Vol.96 (10), p.3537-3543

2000

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The Evolving Role of Bendamustine in Lymphoid Malignancy: Understanding the Drug and Its Mechanism of Action—Introduction

Seminars in hematology, 2011-04, Vol.48, p.S1-S3

Leoni, Lorenzo M

2011

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Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1

Blood, 2002-09, Vol.100 (5), p.1795-1801

2002

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Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis

Gastroenterology (New York, N.Y. 1943), 2002-05, Vol.122 (5), p.1428-1441

2002

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Conclusion and Future Directions

Seminars in hematology, 2011-04, Vol.48, p.S37-S38

Leoni, Lorenzo M

2011

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Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

Modern pathology, 2005-07, Vol.18 (7), p.959-963

2005

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Structural characterization of the Costa Rica décollement: Evidence for seismically-induced fluid pulsing

Earth and planetary science letters, 2007-10, Vol.262 (3), p.413-428

2007

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Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas

Oncogene, 2002-09, Vol.21 (43), p.6598-6605

2002

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The R-Enantiomer of the Nonsteroidal Antiinflammatory Drug Etodolac Binds Retinoid X Receptor and Induces Tumor-Selective Apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (7), p.2525-2530

2005

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Intravesical Toll-like receptor 7 agonist R-837: Optimization of its formulation in an orthotopic mouse model of bladder cancer

International journal of urology, 2010-05, Vol.17 (5), p.483-490

2010

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Substituted Isoquinolines and Quinazolines as Potential Antiinflammatory Agents. Synthesis and Biological Evaluation of Inhibitors of Tumor Necrosis Factor α

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3860-3873

1999

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SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma

Blood, 2005-07, Vol.106 (2), p.706-712

2005

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Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers

Molecular cancer therapeutics, 2005-12, Vol.4 (12), p.1860-1866

2005

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Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells

JNCI : Journal of the National Cancer Institute, 2000-02, Vol.92 (3), p.217-224

2000

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Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy

Cancer biology & therapy, 2005-01, Vol.4 (1), p.90-93

2005

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Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications

The American journal of surgical pathology, 2005-11, Vol.29 (11), p.1497-1504

2005

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Pharmacokinetics and toxicity of intravesical TMX‐101: a preclinical study in pigs

BJU international, 2011-10, Vol.108 (7), p.1210-1214

2011

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Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP

Blood, 2005-06, Vol.105 (11), p.4455-4462

2005

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HIV induces lymphocyte apoptosis by a p53‐initiated, mitochondrial‐mediated mechanism

The FASEB journal, 2001-01, Vol.15 (1), p.5-6

2001

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Induction of an Apoptotic Program in Cell-Free Extracts by 2-Chloro-2′-deoxyadenosine 5′-Triphosphate and Cytochrome c

Proceedings of the National Academy of Sciences - PNAS, 1998-08, Vol.95 (16), p.9567-9571

1998

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Bendamustine (Treanda) Displays a Distinct Pattern of Cytotoxicity and Unique Mechanistic Features Compared with Other Alkylating Agents

Bendamustine: Rescue of an Effective Antineoplastic Agent From the Mid-Twentieth Century

Discovery of allosteric regulators with clinical potential to stabilize alpha-L-iduronidase in mucopolysaccharidosis type I

Activation of the Wnt Signaling Pathway in Chronic Lymphocytic Leukemia

Mechanism of Action: The Unique Pattern of Bendamustine-Induced Cytotoxicity

Deoxyadenosine analogs induce programmed cell death in chronic lymphocytic leukemia cells by damaging the DNA and by directly affecting the mitochondria

The Evolving Role of Bendamustine in Lymphoid Malignancy: Understanding the Drug and Its Mechanism of Action—Introduction

Protection of CLL B cells by a follicular dendritic cell line is dependent on induction of Mcl-1

Immunostimulatory DNA ameliorates experimental and spontaneous murine colitis

Conclusion and Future Directions

Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion

Structural characterization of the Costa Rica décollement: Evidence for seismically-induced fluid pulsing

Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomas

The R-Enantiomer of the Nonsteroidal Antiinflammatory Drug Etodolac Binds Retinoid X Receptor and Induces Tumor-Selective Apoptosis

Intravesical Toll-like receptor 7 agonist R-837: Optimization of its formulation in an orthotopic mouse model of bladder cancer

Substituted Isoquinolines and Quinazolines as Potential Antiinflammatory Agents. Synthesis and Biological Evaluation of Inhibitors of Tumor Necrosis Factor α

SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma

Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers

Indanocine, a microtubule-binding indanone and a selective inducer of apoptosis in multidrug-resistant cancer cells

Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: A potential new target for therapy

Concordant loss of MTAP and p16/CDKN2A expression in gastroesophageal carcinogenesis: evidence of homozygous deletion in esophageal noninvasive precursor lesions and therapeutic implications

Pharmacokinetics and toxicity of intravesical TMX‐101: a preclinical study in pigs

Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP

HIV induces lymphocyte apoptosis by a p53‐initiated, mitochondrial‐mediated mechanism

Induction of an Apoptotic Program in Cell-Free Extracts by 2-Chloro-2′-deoxyadenosine 5′-Triphosphate and Cytochrome c

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