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Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy

Nature communications, 2018-11, Vol.9 (1), p.4931-17, Article 4931

2018

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A KRAS-responsive long non-coding RNA controls microRNA processing

Nature communications, 2021-04, Vol.12 (1), p.2038-2038, Article 2038

2021

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Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia

Leukemia, 2020-05, Vol.34 (5), p.1266-1277

2020

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Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer

Scientific reports, 2019-08, Vol.9 (1), p.11610-6, Article 11610

2019

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Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

Nature communications, 2017-09, Vol.8 (1), p.435-12, Article 435

2017

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Vulnerability of drug‐resistant EML4‐ALK rearranged lung cancer to transcriptional inhibition

EMBO molecular medicine, 2020-07, Vol.12 (7), p.e11099-n/a

2020

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Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation

Cell, 2016-05, Vol.165 (4), p.910-920

2016

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A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)

EBioMedicine, 2021-02, Vol.64, p.103220-103220, Article 103220

2021

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Vasculogenic mimicry in small cell lung cancer

Nature communications, 2016-11, Vol.7 (1), p.13322-13322, Article 13322

2016

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Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma

Nature medicine, 2017-10, Vol.23 (10), p.1167-1175

2017

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High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

Blood, 2010-08, Vol.116 (7), p.1070-1078

2010

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PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways

Scientific reports, 2017-11, Vol.7 (1), p.15441-14, Article 15441

2017

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Targeting Cancer Stem Cell Plasticity Through Modulation of Epidermal Growth Factor and Insulin‐Like Growth Factor Receptor Signaling in Head and Neck Squamous Cell Cancer

Stem cells translational medicine, 2014-09, Vol.3 (9), p.1055-1065

2014

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Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis

Nature communications, 2023-03, Vol.14 (1), p.1680-1680, Article 1680

2023

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Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample

Molecular oncology, 2016-04, Vol.10 (4), p.566-574

2016

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KRAS induces lung tumorigenesis through microRNAs modulation

Cell death & disease, 2018-02, Vol.9 (2), p.219-15, Article 219

2018

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GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers

Oncogene, 2018-03, Vol.37 (10), p.1340-1353

2018

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Frequent Derepression of the Mesenchymal Transcription Factor Gene FOXC1 in Acute Myeloid Leukemia

Cancer cell, 2015-09, Vol.28 (3), p.329-342

2015

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Text-based over-representation analysis of microarray gene lists with annotation bias

Nucleic acids research, 2009-06, Vol.37 (11), p.e79

2009

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Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling

Molecular therapy, 2015-04, Vol.23 (4), p.746-756

2015

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RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

PLoS genetics, 2016-01, Vol.12 (1), p.e1005814

2016

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A global non-coding RNA system modulates fission yeast protein levels in response to stress

Nature communications, 2014-05, Vol.5 (1), p.3947-3947, Article 3947

2014

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Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors

Blood, 2017-07, Vol.130 (3), p.271-284

2017

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Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

Genome medicine, 2015-09, Vol.7 (1), p.98-98, Article 98

2015

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Tongue carcinoma infrequently harbor common actionable genetic alterations

BMC cancer, 2014-09, Vol.14 (1), Article 679

2014

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Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy

A KRAS-responsive long non-coding RNA controls microRNA processing

Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia

Analysis of circulating cell-free DNA identifies KRAS copy number gain and mutation as a novel prognostic marker in Pancreatic cancer

Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time

Vulnerability of drug‐resistant EML4‐ALK rearranged lung cancer to transcriptional inhibition

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation

A chemical genetic screen identifies Aurora kinases as a therapeutic target in EGFR T790M negative, gefitinib-resistant head and neck squamous cell carcinoma (HNSCC)

Vasculogenic mimicry in small cell lung cancer

Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma

High-throughput immunoglobulin repertoire analysis distinguishes between human IgM memory and switched memory B-cell populations

PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways

Targeting Cancer Stem Cell Plasticity Through Modulation of Epidermal Growth Factor and Insulin‐Like Growth Factor Receptor Signaling in Head and Neck Squamous Cell Cancer

Single cell analysis in head and neck cancer reveals potential immune evasion mechanisms during early metastasis

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample

KRAS induces lung tumorigenesis through microRNAs modulation

GNA13 expression promotes drug resistance and tumor-initiating phenotypes in squamous cell cancers

Frequent Derepression of the Mesenchymal Transcription Factor Gene FOXC1 in Acute Myeloid Leukemia

Text-based over-representation analysis of microarray gene lists with annotation bias

Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling

RUNX1B Expression Is Highly Heterogeneous and Distinguishes Megakaryocytic and Erythroid Lineage Fate in Adult Mouse Hematopoiesis

A global non-coding RNA system modulates fission yeast protein levels in response to stress

Mouse RUNX1C regulates premegakaryocytic/erythroid output and maintains survival of megakaryocyte progenitors

Mutational landscapes of tongue carcinoma reveal recurrent mutations in genes of therapeutic and prognostic relevance

Tongue carcinoma infrequently harbor common actionable genetic alterations

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