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Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (12), p.127174-127174, Article 127174

2020

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Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.2915-2929

2020

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A Transient N−O-Linked Pauson−Khand Strategy for the Synthesis of the Deschloro Carbocyclic Core of the Palau'amines and Styloguanidines

Organic letters, 2003-06, Vol.5 (13), p.2203-2206

2003

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Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

ACS medicinal chemistry letters, 2021-05, Vol.12 (5), p.782-790

2021

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2,4,6-Triarylchalcogenopyrylium Dyes Related in Structure to the Antitumor Agent AA1 as in Vitro Sensitizers for the Photodynamic Therapy of Cancer

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3942-3952

1999

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Design, Synthesis, and Biological Evaluation of Novel Potent and Selective αvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.926-934

2005

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A Selenopyrylium Photosensitizer for Photodynamic Therapy Related in Structure to the Antitumor Agent AA1 with Potent in Vivo Activity and No Long-Term Skin Photosensitization

Journal of medicinal chemistry, 2000-11, Vol.43 (23), p.4488-4498

2000

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Synthesis and Evaluation of Chalcogenopyrylium Dyes as Potential Sensitizers for the Photodynamic Therapy of Cancer

Journal of medicinal chemistry, 1999-09, Vol.42 (19), p.3953-3964

1999

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Synthesis of 3,4-substituted cyclopentenones via an intramolecular Pauson–Khand reaction of NO linked enynes

Tetrahedron letters, 2000-12, Vol.41 (49), p.9393-9396

2000

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Chalcogen(IV)−Chalcogen(II) Redox Cycles. 1. Halogenation of Organic Substrates with Dihaloselenium(IV) and -tellurium(IV) Derivatives. Dehalogenation of Vicinal Dibromides with Diaryl Tellurides

Organometallics, 1996-10, Vol.15 (20), p.4285-4292

1996

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Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo

Molecular cancer therapeutics, 2006-01, Vol.5 (1), p.160-169

2006

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Design, synthesis, and biological evaluation of novel potent and selective alphavbeta3/alphavbeta5 integrin dual inhibitors with improved bioavailability. Selection of the molecular core

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.926-934

2005

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Design, Synthesis, and Biological Evaluation of Novel Potent and Selective α v β 3 /α v β 5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.926-934

2005

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Corrigendum to “Synthesis of 3,4-substituted cyclopentenones via an intramolecular Pauson–Khand reaction of NO linked enynes”: [Tetrahedron Lett. 41 (2000) 9393]

Tetrahedron letters, 2003-05, Vol.44 (20), p.3995-3995

2003

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ChemInform Abstract: Synthesis of 3,4-Substituted Cyclopentenones via an Intramolecular Pauson-Khand Reaction of N-O Linked Enynes

ChemInform, 2001-03, Vol.32 (10), p.no-no

2001

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Development of National Standardized All-Hazard Disaster Core Competencies for Acute Care Physicians, Nurses, and EMS Professionals

Annals of emergency medicine, 2012-03, Vol.59 (3), p.196-208.e1

2012

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Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy

Frontiers in neuroscience, 2013-01, Vol.7, p.246-246

2013

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Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice: Molecular Genetic Dissection of Non-REM and REM Sleep Regulatory Processes

Neuron (Cambridge, Mass.), 2003-06, Vol.38 (5), p.715-730

2003

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Role of Intracoronary Adrenaline in the Treatment of No-Reflow Phenomenon in Patients Undergoing Percutaneous Coronary Intervention

Curēus (Palo Alto, CA), 2024-05

2024

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Nicotinic Activation of Laterodorsal Tegmental Neurons: Implications for Addiction to Nicotine

Neuropsychopharmacology (New York, N.Y.), 2009-11, Vol.34 (12), p.2529-2547

2009

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Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

The Journal of biological chemistry, 2017-10, Vol.292 (43), p.17963-17974

2017

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Interaction Dynamics: The Interface of Humans and Smart Machines [Scanning the Issue]

Proceedings of the IEEE, 2012-03, Vol.100 (3), p.567-570

2012

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From anecdotes to quantification: advances in characterizing volcanic eruption impacts on the built environment

Bulletin of volcanology, 2022, Vol.84 (1), Article 7

2022

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Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: Implications for the heightened adolescent susceptibility to nicotine addiction

Neuropharmacology, 2014-10, Vol.85, p.263-283

2014

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Hypocretin/Orexin Peptide Signaling in the Ascending Arousal System: Elevation of Intracellular Calcium in the Mouse Dorsal Raphe and Laterodorsal Tegmentum

Journal of neurophysiology, 2004-07, Vol.92 (1), p.221-235

2004

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Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach

Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease

A Transient N−O-Linked Pauson−Khand Strategy for the Synthesis of the Deschloro Carbocyclic Core of the Palau'amines and Styloguanidines

Discovery of a Potent and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase with Oral Anti-Inflammatory Activity

2,4,6-Triarylchalcogenopyrylium Dyes Related in Structure to the Antitumor Agent AA1 as in Vitro Sensitizers for the Photodynamic Therapy of Cancer

Design, Synthesis, and Biological Evaluation of Novel Potent and Selective αvβ3/αvβ5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

A Selenopyrylium Photosensitizer for Photodynamic Therapy Related in Structure to the Antitumor Agent AA1 with Potent in Vivo Activity and No Long-Term Skin Photosensitization

Synthesis and Evaluation of Chalcogenopyrylium Dyes as Potential Sensitizers for the Photodynamic Therapy of Cancer

Synthesis of 3,4-substituted cyclopentenones via an intramolecular Pauson–Khand reaction of NO linked enynes

Chalcogen(IV)−Chalcogen(II) Redox Cycles. 1. Halogenation of Organic Substrates with Dihaloselenium(IV) and -tellurium(IV) Derivatives. Dehalogenation of Vicinal Dibromides with Diaryl Tellurides

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo

Design, synthesis, and biological evaluation of novel potent and selective alphavbeta3/alphavbeta5 integrin dual inhibitors with improved bioavailability. Selection of the molecular core

Design, Synthesis, and Biological Evaluation of Novel Potent and Selective α v β 3 /α v β 5 Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

Corrigendum to “Synthesis of 3,4-substituted cyclopentenones via an intramolecular Pauson–Khand reaction of NO linked enynes”: [Tetrahedron Lett. 41 (2000) 9393]

ChemInform Abstract: Synthesis of 3,4-Substituted Cyclopentenones via an Intramolecular Pauson-Khand Reaction of N-O Linked Enynes

Development of National Standardized All-Hazard Disaster Core Competencies for Acute Care Physicians, Nurses, and EMS Professionals

Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy

Distinct Narcolepsy Syndromes in Orexin Receptor-2 and Orexin Null Mice: Molecular Genetic Dissection of Non-REM and REM Sleep Regulatory Processes

Role of Intracoronary Adrenaline in the Treatment of No-Reflow Phenomenon in Patients Undergoing Percutaneous Coronary Intervention

Nicotinic Activation of Laterodorsal Tegmental Neurons: Implications for Addiction to Nicotine

Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

Interaction Dynamics: The Interface of Humans and Smart Machines [Scanning the Issue]

From anecdotes to quantification: advances in characterizing volcanic eruption impacts on the built environment

Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: Implications for the heightened adolescent susceptibility to nicotine addiction

Hypocretin/Orexin Peptide Signaling in the Ascending Arousal System: Elevation of Intracellular Calcium in the Mouse Dorsal Raphe and Laterodorsal Tegmentum

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