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Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

Environmental science & technology, 2016-05, Vol.50 (9), p.4579-4586

2016

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Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction

PLoS computational biology, 2016-02, Vol.12 (2), p.e1004495-e1004495

2016

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Aggregate exposure pathways in support of risk assessment

Current opinion in toxicology, 2018-06, Vol.9, p.8-13

2018

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Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation

Frontiers in toxicology, 2022-04, Vol.4, p.894569-894569

2022

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Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making

Toxicological sciences, 2018-04, Vol.162 (2), p.341-348

2018

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Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

Regulatory toxicology and pharmacology, 2017-11, Vol.90 (C), p.104-115

2017

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Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling

Toxicological sciences, 2016-05, Vol.151 (1), p.57-70

2016

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Metabolomic, behavioral, and reproductive effects of the synthetic estrogen 17 α-ethinylestradiol on the unionid mussel Lampsilis fasciola

Aquatic toxicology, 2014-05, Vol.150, p.103-116

2014

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A weight of evidence approach to investigate potential common mechanisms in pesticide groups to support cumulative risk assessment: A case study with dinitroaniline pesticides

Regulatory toxicology and pharmacology, 2019-10, Vol.107 (C), p.104419, Article 104419

2019

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Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates

Toxicology in vitro, 2020-08, Vol.66 (C), p.104855-104855, Article 104855

2020

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Refining the aggregate exposure pathway

Environmental science--processes & impacts, 2018-03, Vol.2 (3), p.428-436

2018

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Extending the toxicity-testing paradigm for freshwater mussels: Assessing chronic reproductive effects of the synthetic estrogen 17α-ethinylestradiol on the unionid mussel Elliptio complanata

Comparative biochemistry and physiology. Toxicology & pharmacology, 2017-01, Vol.191, p.14-25

2017

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Assessing toxicity of contaminants in riverine suspended sediments to freshwater mussels

Environmental toxicology and chemistry, 2017-02, Vol.36 (2), p.395-407

2017

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A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways

Environmental health perspectives, 2016-01, Vol.124 (1), p.53-60

2016

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Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays

Environmental science & technology, 2016-06, Vol.50 (11), p.5961-5971

2016

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Metabolomic, behavioral, and reproductive effects of the aromatase inhibitor fadrozole hydrochloride on the unionid mussel Lampsilis fasciola

General and comparative endocrinology, 2014-09, Vol.206, p.213-226

2014

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Zooplankton community structure, micro-zooplankton grazing impact, and seston energy content in the St. Johns river system, Florida as influenced by the toxic cyanobacterium Cylindrospermopsis raciborskii

Hydrobiologia, 2005-03, Vol.537 (1-3), p.89-97

2005

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Expanding on Successful Concepts, Models, and Organization

Environmental science & technology, 2016-09, Vol.50 (17), p.8921-8922

2016

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A workflow for identifying metabolically active chemicals to complement in vitro toxicity screening

Computational toxicology, 2018-05, Vol.6 (C), p.71-83

2018

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Environmental controls upon picophytoplankton growth and biomass in a eutrophic estuary

Aquatic microbial ecology : international journal, 2011-01, Vol.63 (2), p.133-143

2011

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The Impact of the Housing Market Boom and Bust on Consumption Spending

Business economics (Cleveland, Ohio), 2010-04, Vol.45 (2), p.83-93

LEONARD, JEREMY A.

2010

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Supporting systems science through in silico applications: A focus on informing metabolic mechanisms

Current opinion in toxicology, 2019-08, Vol.16 (C), p.1-8

Leonard, Jeremy A.

2019

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Corrigendum to “Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making”

Toxicological sciences, 2018-04, Vol.162 (2), p.724-724

2018

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Tiered approaches for screening and prioritizing chemicals through integration of pharmacokinetics and exposure information with in vitro dose-response data

Computational toxicology, 2019-11, Vol.12 (C), p.100101, Article 100101

2019

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Completing the link between exposure science and toxicology for improved environmental health decision making: The aggregate exposure pathway framework

Environmental science & technology, 2016-01, Vol.136 (2)

2016

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Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

Developing a Physiologically-Based Pharmacokinetic Model Knowledgebase in Support of Provisional Model Construction

Aggregate exposure pathways in support of risk assessment

Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation

Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making

Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications

Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling

Metabolomic, behavioral, and reproductive effects of the synthetic estrogen 17 α-ethinylestradiol on the unionid mussel Lampsilis fasciola

A weight of evidence approach to investigate potential common mechanisms in pesticide groups to support cumulative risk assessment: A case study with dinitroaniline pesticides

Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates

Refining the aggregate exposure pathway

Extending the toxicity-testing paradigm for freshwater mussels: Assessing chronic reproductive effects of the synthetic estrogen 17α-ethinylestradiol on the unionid mussel Elliptio complanata

Assessing toxicity of contaminants in riverine suspended sediments to freshwater mussels

A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways

Evaluating the Impact of Uncertainties in Clearance and Exposure When Prioritizing Chemicals Screened in High-Throughput Assays

Metabolomic, behavioral, and reproductive effects of the aromatase inhibitor fadrozole hydrochloride on the unionid mussel Lampsilis fasciola

Zooplankton community structure, micro-zooplankton grazing impact, and seston energy content in the St. Johns river system, Florida as influenced by the toxic cyanobacterium Cylindrospermopsis raciborskii

Expanding on Successful Concepts, Models, and Organization

A workflow for identifying metabolically active chemicals to complement in vitro toxicity screening

Environmental controls upon picophytoplankton growth and biomass in a eutrophic estuary

The Impact of the Housing Market Boom and Bust on Consumption Spending

Supporting systems science through in silico applications: A focus on informing metabolic mechanisms

Corrigendum to “Challenges Associated With Applying Physiologically Based Pharmacokinetic Modeling for Public Health Decision-Making”

Tiered approaches for screening and prioritizing chemicals through integration of pharmacokinetics and exposure information with in vitro dose-response data

Completing the link between exposure science and toxicology for improved environmental health decision making: The aggregate exposure pathway framework

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