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Advances in the Evolutionary Understanding of MHC Polymorphism

Trends in genetics, 2020-04, Vol.36 (4), p.298-311

2020

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Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

Nature medicine, 2019-11, Vol.25 (11), p.1715-1720

2019

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COMPUTATIONAL PREDICTION OF MHC II-ANTIGEN BINDING SUPPORTS DIVERGENT ALLELE ADVANTAGE AND EXPLAINS TRANS-SPECIES POLYMORPHISM

Evolution, 2011-08, Vol.65 (8), p.2380-2390

Lenz, Tobias L.

2011

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Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations

Nature communications, 2012-01, Vol.3 (1), p.621-621, Article 621

2012

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HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation

Molecular biology and evolution, 2020-03, Vol.37 (3), p.639-650

2020

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Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations

PLoS biology, 2019-01, Vol.17 (1), p.e3000131-e3000131

2019

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Genomics of divergence along a continuum of parapatric population differentiation

PLoS genetics, 2015-02, Vol.11 (2), p.e1004966-e1004966

2015

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Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

Nature genetics, 2015-08, Vol.47 (8), p.898-905

2015

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Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond

Frontiers in immunology, 2022-09, Vol.13, p.944872-944872

2022

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Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection

Molecular biology and evolution, 2016-10, Vol.33 (10), p.2555-2564

2016

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Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins

Frontiers in immunology, 2023-03, Vol.14, p.1107266-1107266

2023

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Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection

Molecular biology and evolution, 2018-09, Vol.35 (9), p.2145-2158

2018

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The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders

Blood, 2021-12, Vol.138 (26), p.2781-2798

2021

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Common Denominators in the Immunobiology of IgG4 Autoimmune Diseases: What Do Glomerulonephritis, Pemphigus Vulgaris, Myasthenia Gravis, Thrombotic Thrombocytopenic Purpura and Autoimmune Encephalitis Have in Common?

Frontiers in immunology, 2021-01, Vol.11, p.605214-605214

2021

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Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome-wide digital gene expression analysis

Molecular ecology, 2013-02, Vol.22 (3), p.774-786

2013

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Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Nature communications, 2018-05, Vol.9 (1), p.1569-11, Article 1569

2018

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Intronic primers reveal unexpectedly high major histocompatibility complex diversity in Antarctic fur seals

Scientific reports, 2022-10, Vol.12 (1), p.17933-17933, Article 17933

2022

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Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles

Human molecular genetics, 2019-06, Vol.28 (12), p.2078-2092

2019

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Extensive copy-number variation of young genes across stickleback populations

PLoS genetics, 2014-12, Vol.10 (12), p.e1004830-e1004830

2014

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Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data

BMC bioinformatics, 2021-08, Vol.22 (1), p.1-405, Article 405

2021

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Erratum for Wichers-Misterek et al., "A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission"

mBio, 2023-10, Vol.14 (5), p.e0178623-e0178623

2023

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A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission

mBio, 2023-02, Vol.14 (1), p.e0331822

2023

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Ancient DNA Study in Medieval Europeans Shows an Association Between HLA-DRB103 and Paratyphoid Fever

Frontiers in immunology, 2021-07, Vol.12, p.691475-691475

2021

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Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations

Scientific reports, 2020-04, Vol.10 (1), p.7339-7339, Article 7339

2020

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Evaluation of Genetic Diversity and Parasite-Mediated Selection of MHC Class I Genes in Emberiza godlewskii (Passeriformes: Emberizidae)

Diversity (Basel), 2022-11, Vol.14 (11), p.925

2022

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Advances in the Evolutionary Understanding of MHC Polymorphism

Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

COMPUTATIONAL PREDICTION OF MHC II-ANTIGEN BINDING SUPPORTS DIVERGENT ALLELE ADVANTAGE AND EXPLAINS TRANS-SPECIES POLYMORPHISM

Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations

HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation

Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations

Genomics of divergence along a continuum of parapatric population differentiation

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond

Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection

Challenges and opportunities in analyzing and modeling peptide presentation by HLA-II proteins

Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection

The similarity of class II HLA genotypes defines patterns of autoreactivity in idiopathic bone marrow failure disorders

Common Denominators in the Immunobiology of IgG4 Autoimmune Diseases: What Do Glomerulonephritis, Pemphigus Vulgaris, Myasthenia Gravis, Thrombotic Thrombocytopenic Purpura and Autoimmune Encephalitis Have in Common?

Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome-wide digital gene expression analysis

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans

Intronic primers reveal unexpectedly high major histocompatibility complex diversity in Antarctic fur seals

Construction and benchmarking of a multi-ethnic reference panel for the imputation of HLA class I and II alleles

Extensive copy-number variation of young genes across stickleback populations

Immunopeptidomics toolkit library (IPTK): a python-based modular toolbox for analyzing immunopeptidomics data

Erratum for Wichers-Misterek et al., "A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission"

A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission

Ancient DNA Study in Medieval Europeans Shows an Association Between HLA-DRB103 and Paratyphoid Fever

Targeted analysis of polymorphic loci from low-coverage shotgun sequence data allows accurate genotyping of HLA genes in historical human populations

Evaluation of Genetic Diversity and Parasite-Mediated Selection of MHC Class I Genes in Emberiza godlewskii (Passeriformes: Emberizidae)

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