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Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches

Pharmaceutics, 2019-08, Vol.11 (8), p.411

2019

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Regional intestinal drug permeation: Biopharmaceutics and drug development

European journal of pharmaceutical sciences, 2014-06, Vol.57 (SI), p.333-341

Lennernas, Hans

2014

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Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation

Biomedicine & pharmacotherapy, 2023-06, Vol.162, p.114644-114644, Article 114644

2023

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Human in Vivo Regional Intestinal Permeability: Importance for Pharmaceutical Drug Development

Molecular pharmaceutics, 2014-01, Vol.11 (1), p.12-23

Lennernäs, Hans

2014

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Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective

Molecules (Basel, Switzerland), 2020-06, Vol.25 (12), p.2861

2020

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Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

Frontiers in pharmacology, 2021-05, Vol.12, p.681417-681417

2021

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In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations

Molecular pharmaceutics, 2017-12, Vol.14 (12), p.4233-4242

2017

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Human in Vivo Regional Intestinal Permeability: Quantitation Using Site-Specific Drug Absorption Data

Molecular pharmaceutics, 2015-06, Vol.12 (6), p.2026-2039

2015

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Regional Intestinal Permeability in Rats: A Comparison of Methods

Molecular pharmaceutics, 2017-12, Vol.14 (12), p.4252-4261

2017

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Gastroparesis, metoclopramide, and tardive dyskinesia: Risk revisited

Neurogastroenterology and motility, 2019-11, Vol.31 (11), p.e13617-e13617

2019

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Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma

International journal of molecular sciences, 2021-12, Vol.22 (23), p.13051

2021

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Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10762

2021

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In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: Application of the mechanistic absorption model GI-Sim

European journal of pharmaceutical sciences, 2013-07, Vol.49 (4), p.679-698

2013

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Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma

Scientific reports, 2023-01, Vol.13 (1), p.748-748, Article 748

2023

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The Fraction Dose Absorbed, in Humans, and High Jejunal Human Permeability Relationship

Molecular pharmaceutics, 2012-06, Vol.9 (6), p.1847-1851

2012

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Direct In Vivo Human Intestinal Permeability (Peff) Determined with Different Clinical Perfusion and Intubation Methods

Journal of pharmaceutical sciences, 2015-09, Vol.104 (9), p.2702-2726

2015

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Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model

Molecular pharmaceutics, 2019-07, Vol.16 (7), p.3053-3064

2019

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Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma

Cells (Basel, Switzerland), 2022-02, Vol.11 (4), p.632

2022

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Toward an Increased Understanding of the Barriers to Colonic Drug Absorption in Humans: Implications for Early Controlled Release Candidate Assessment

Molecular pharmaceutics, 2009-02, Vol.6 (1), p.60-73

2009

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Regional Intestinal Permeability of Three Model Drugs in Human

Molecular pharmaceutics, 2016-09, Vol.13 (9), p.3013-3021

2016

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Pulmonary drug absorption and systemic exposure in human: Predictions using physiologically based biopharmaceutics modeling

European journal of pharmaceutics and biopharmaceutics, 2020-11, Vol.156, p.191-202

2020

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Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids

Analytica chimica acta, 2024-08, Vol.1316, p.342811, Article 342811

2024

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Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms

Molecular pharmaceutics, 2016-09, Vol.13 (9), p.3022-3033

2016

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Clinical pharmacokinetics of atorvastatin

Clinical pharmacokinetics, 2003-01, Vol.42 (13), p.1141-1160

Lennernas, Hans

2003

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Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition

Molecular pharmaceutics, 2014-06, Vol.11 (6), p.1727-1738

2014

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Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches

Regional intestinal drug permeation: Biopharmaceutics and drug development

Review on the effect of chemotherapy on the intestinal barrier: Epithelial permeability, mucus and bacterial translocation

Human in Vivo Regional Intestinal Permeability: Importance for Pharmaceutical Drug Development

Antibody-Drug Conjugates and Targeted Treatment Strategies for Hepatocellular Carcinoma: A Drug-Delivery Perspective

Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

In Vivo Mechanisms of Intestinal Drug Absorption from Aprepitant Nanoformulations

Human in Vivo Regional Intestinal Permeability: Quantitation Using Site-Specific Drug Absorption Data

Regional Intestinal Permeability in Rats: A Comparison of Methods

Gastroparesis, metoclopramide, and tardive dyskinesia: Risk revisited

Limitations and Possibilities of Transarterial Chemotherapeutic Treatment of Hepatocellular Carcinoma

Melatonin-Activated Receptor Signaling Pathways Mediate Protective Effects on Surfactant-Induced Increase in Jejunal Mucosal Permeability in Rats

In silico predictions of gastrointestinal drug absorption in pharmaceutical product development: Application of the mechanistic absorption model GI-Sim

Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma

The Fraction Dose Absorbed, in Humans, and High Jejunal Human Permeability Relationship

Direct In Vivo Human Intestinal Permeability (Peff) Determined with Different Clinical Perfusion and Intubation Methods

Pulmonary Dissolution of Poorly Soluble Compounds Studied in an ex Vivo Rat Lung Model

Drug Resistance and Endoplasmic Reticulum Stress in Hepatocellular Carcinoma

Toward an Increased Understanding of the Barriers to Colonic Drug Absorption in Humans: Implications for Early Controlled Release Candidate Assessment

Regional Intestinal Permeability of Three Model Drugs in Human

Pulmonary drug absorption and systemic exposure in human: Predictions using physiologically based biopharmaceutics modeling

Ammonium bicarbonate buffers combined with hybrid surface technology columns improve the peak shape of strongly tailing lipids

Regional Intestinal Permeability in Dogs: Biopharmaceutical Aspects for Development of Oral Modified-Release Dosage Forms

Clinical pharmacokinetics of atorvastatin

Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition

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