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Exploring drug repositioning possibilities of kinase inhibitors via molecular simulation

Molecular informatics, 2024-09, Vol.43 (9), p.e202300336-n/a

2024

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Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

Biomedicine & pharmacotherapy, 2023-12, Vol.169, p.115905-115905, Article 115905

2023

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Discovery of 4‐(4‐aminophenyl)‐6‐phenylisoxazolo[3,4‐b]pyridine‐3‐amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia

Drug development research, 2023-04, Vol.84 (2), p.296-311

2023

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Natural products as potential lead compounds to develop new antiviral drugs over the past decade

European journal of medicinal chemistry, 2023-11, Vol.260, p.115726, Article 115726

2023

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Unraveling the Promise of RET Inhibitors in Precision Cancer Therapy by Targeting RET Mutations

Journal of medicinal chemistry, 2024-03, Vol.67 (6), p.4346-4375

2024

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Challenges for the development of mutant isocitrate dehydrogenases 1 inhibitors to treat glioma

European journal of medicinal chemistry, 2023-09, Vol.257, p.115464-115464, Article 115464

2023

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Research strategies of small molecules as chemotherapeutics to overcome multiple myeloma resistance

European journal of medicinal chemistry, 2024-05, Vol.271, p.116435-116435, Article 116435

2024

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Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia

Bioorganic & medicinal chemistry, 2024-02, Vol.100, p.117631-117631, Article 117631

2024

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Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia

Bioorganic & medicinal chemistry, 2022-09, Vol.70, p.116937-116937, Article 116937

2022

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Scaffold-hopping of Linifanib to Design 6-phenylisoxazolo[3,4-b]pyridin-3-amine Derivatives as FLT3 Inhibitors for Treating Acute Myeloid Leukemia

Letters in drug design & discovery, 2024-08, Vol.21 (10), p.1833-1846

2024

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Design and synthesis of selective FLT3 inhibitors via exploration of back pocket II

Future medicinal chemistry, 2023-01, Vol.15 (1), p.57-71

2023

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A SAR Study on a Class of 6-(Trifluoromethyl)-pyridine Derivatives as RORγt Inverse Agonists

Letters in drug design & discovery, 2024-09, Vol.21 (12), p.2359-2373

2024

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Synthesis and Biological Evaluation of 2-Amino-1-phenyl-benzimidazole Derivatives as BACE1 Inhibitors

Letters in drug design & discovery, 2024-06, Vol.21 (7), p.1252-1262

2024

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Comparative metabolites in plasma and urine of normal and type 2 diabetic rats after oral administration of the traditional Chinese scutellaria-coptis herb couple by ultra performance liquid chromatography-tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014-08, Vol.965, p.27-32

2014

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Identification of the metabolites of myricitrin produced by human intestinal bacteria in vitro using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Expert opinion on drug metabolism & toxicology, 2014-07, Vol.10 (7), p.921-931

2014

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Discovery of SILA-123 as a Highly Potent FLT3 Inhibitor for the Treatment of Acute Myeloid Leukemia with Various FLT3 Mutations

Journal of medicinal chemistry, 2024-09

2024

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Correction to “Discovery of RORγ Allosteric Fluorescent Probes and Their Application: Fluorescence Polarization, Screening, and Bioimaging”

Journal of medicinal chemistry, 2024-04, Vol.67 (7), p.5960-5961

2024

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Discovery of RORγ Allosteric Fluorescent Probes and Their Application: Fluorescence Polarization, Screening, and Bioimaging

Journal of medicinal chemistry, 2024-03, Vol.67 (5), p.4194-4224

2024

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Discovery of 4‐(4‐aminophenyl)‐6‐phenylisoxazolopyridine‐3‐amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia

Drug development research, 2023-04, Vol.84 (2), p.296-311

2023

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How graphene oxide affects shape memory properties and strength of poly( l -lactide-co-ε-caprolactone)

Journal of intelligent material systems and structures, 2020-11, Vol.31 (18), p.2152-2164

2020

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Atomistic investigation of the shape-memory effect of amorphous poly(L-lactide) with different molecular weights

Smart materials and structures, 2020-01, Vol.29 (1), p.15040

2020

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The shape memory properties of multi-layer graphene reinforced poly(L-lactide-co-ϵ-caprolactone) by an atomistic investigation

Smart materials and structures, 2021-05, Vol.30 (5), p.55005

2021

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Compound heterozygous mutations in CYP1B1 gene leads to severe primary congenital glaucoma phenotype

International journal of ophthalmology, 2019-06, Vol.12 (6)

2019

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Functional analysis of the novel mitochondrial tRNATrp and tRNASer(AGY) variants associated with type 2 diabetes mellitus

World journal of diabetes, 2024-08, Vol.15 (8), p.1753-1763

2024

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Functional analysis of the novel mitochondrial tRNA Trp and tRNA Ser(AGY) variants associated with type 2 diabetes mellitus

World journal of diabetes, 2024-08, Vol.15 (8), p.1753-1763

2024

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Exploring drug repositioning possibilities of kinase inhibitors via molecular simulation

Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

Discovery of 4‐(4‐aminophenyl)‐6‐phenylisoxazolo[3,4‐b]pyridine‐3‐amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia

Natural products as potential lead compounds to develop new antiviral drugs over the past decade

Unraveling the Promise of RET Inhibitors in Precision Cancer Therapy by Targeting RET Mutations

Challenges for the development of mutant isocitrate dehydrogenases 1 inhibitors to treat glioma

Research strategies of small molecules as chemotherapeutics to overcome multiple myeloma resistance

Design and synthesis 1H-Pyrrolo[2,3-b]pyridine derivatives as FLT3 inhibitors for the treatment of Acute myeloid Leukemia

Synthesis and biological evaluation of 4-(4-aminophenyl)-6-methylisoxazolo[3,4-b] pyridin-3-amine covalent inhibitors as potential agents for the treatment of acute myeloid leukemia

Scaffold-hopping of Linifanib to Design 6-phenylisoxazolo[3,4-b]pyridin-3-amine Derivatives as FLT3 Inhibitors for Treating Acute Myeloid Leukemia

Design and synthesis of selective FLT3 inhibitors via exploration of back pocket II

A SAR Study on a Class of 6-(Trifluoromethyl)-pyridine Derivatives as RORγt Inverse Agonists

Synthesis and Biological Evaluation of 2-Amino-1-phenyl-benzimidazole Derivatives as BACE1 Inhibitors

Comparative metabolites in plasma and urine of normal and type 2 diabetic rats after oral administration of the traditional Chinese scutellaria-coptis herb couple by ultra performance liquid chromatography-tandem mass spectrometry

Identification of the metabolites of myricitrin produced by human intestinal bacteria in vitro using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

Discovery of SILA-123 as a Highly Potent FLT3 Inhibitor for the Treatment of Acute Myeloid Leukemia with Various FLT3 Mutations

Correction to “Discovery of RORγ Allosteric Fluorescent Probes and Their Application: Fluorescence Polarization, Screening, and Bioimaging”

Discovery of RORγ Allosteric Fluorescent Probes and Their Application: Fluorescence Polarization, Screening, and Bioimaging

Discovery of 4‐(4‐aminophenyl)‐6‐phenylisoxazolopyridine‐3‐amine derivatives as novel FLT3 covalent inhibitors for the intervention of acute myeloid leukemia

How graphene oxide affects shape memory properties and strength of poly( l -lactide-co-ε-caprolactone)

Atomistic investigation of the shape-memory effect of amorphous poly(L-lactide) with different molecular weights

The shape memory properties of multi-layer graphene reinforced poly(L-lactide-co-ϵ-caprolactone) by an atomistic investigation

Compound heterozygous mutations in CYP1B1 gene leads to severe primary congenital glaucoma phenotype

Functional analysis of the novel mitochondrial tRNATrp and tRNASer(AGY) variants associated with type 2 diabetes mellitus

Functional analysis of the novel mitochondrial tRNA Trp and tRNA Ser(AGY) variants associated with type 2 diabetes mellitus

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