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The Mitochondrial Production of Reactive Oxygen Species: Mechanisms and Implications in Human Pathology

IUBMB life, 2001-09, Vol.52 (3‐5), p.159-164

Lenaz, Giorgio

2001

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Is supercomplex organization of the respiratory chain required for optimal electron transfer activity?

Biochimica et biophysica acta, 2008-07, Vol.1777 (7-8), p.740-746

2008

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Role of Mitochondria in Oxidative Stress and Aging

Annals of the New York Academy of Sciences, 2002-04, Vol.959 (1), p.199-213

2002

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The primary role of glutathione against nuclear DNA damage of striatum induced by permethrin in rats

Neuroscience, 2010-06, Vol.168 (1), p.2-10

2010

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The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron–sulfur cluster N2

FEBS letters, 2001-09, Vol.505 (3), p.364-368

2001

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Role of mitochondria in oxidative stress and ageing

Biochimica et biophysica acta, 1998-08, Vol.1366 (1), p.53-67

Lenaz, Giorgio

1998

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Increased state 4 mitochondrial respiration and swelling in early post-ischemic reperfusion of rat heart

FEBS letters, 2004-04, Vol.563 (1), p.161-164

2004

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Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone)

Journal of bioenergetics and biomembranes, 2008-04, Vol.40 (2), p.85-93

2008

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Mitochondrial bioenergetics in aging

Biochimica et biophysica acta, 2000-08, Vol.1459 (2-3), p.397-404

2000

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Rhodamine 123 as a probe of mitochondrial membrane potential: evaluation of proton flux through F 0 during ATP synthesis

Biochimica et biophysica acta. Bioenergetics, 2003-09, Vol.1606 (1), p.137-146

2003

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Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone

Biochemical and biophysical research communications, 2006-01, Vol.339 (1), p.362-366

2006

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Relevance of mitochondrial genetics and metabolism in cancer development

Cold Spring Harbor perspectives in biology, 2013-02, Vol.5 (2), p.a011411-a011411

2013

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Hyperoxia fully protects mitochondria of explanted livers

Journal of bioenergetics and biomembranes, 2011-12, Vol.43 (6), p.673-682

2011

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The Role of DT-Diaphorase in the Maintenance of the Reduced Antioxidant Form of Coenzyme Q in Membrane Systems

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (6), p.2528-2532

1996

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An Open-Label, Dose-Escalating Phase I Study of Elsamitrucin (SPI 28090) in Treatment of Malignant Solid Tumors in Dogs

Journal of veterinary internal medicine, 2011-07, Vol.25 (4), p.897-902

2011

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The effects of idebenone on mitochondrial bioenergetics

Biochimica et biophysica acta, 2012-02, Vol.1817 (2), p.363-369

2012

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A critical appraisal of the mitochondrial coenzyme Q pool

FEBS Letters, 2001-12, Vol.509 (2), p.151-155

Lenaz, Giorgio

2001

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Biochemical features of mtDNA 14484 (ND6/m64V) point mutation associated with Leber's hereditary optic neuropathy

Annals of neurology, 1999-03, Vol.45 (3), p.320-328

1999

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The mitochondrial respiratory chain is partially organized in a supercomplex assembly: kinetic evidence using flux control analysis

The Journal of biological chemistry, 2004-08, Vol.279 (35), p.36562

2004

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The Mitochondrial Production of Reactive Oxygen Species in Relation to Aging and Pathology

Annals of the New York Academy of Sciences, 2004-04, Vol.1011 (1), p.86-100

2004

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Control of respiration by nitric oxide in Keilin-Hartree particles, mitochondria and SH-SY5Y neuroblastoma cells

Cellular and molecular life sciences : CMLS, 2003-08, Vol.60 (8), p.1752-1759

2003

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Quinone specificity of Complex I

Biochimica et biophysica acta, 1998-05, Vol.1364 (2), p.207-221

Lenaz, Giorgio

1998

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Hyperbaric oxygen reduces rat liver preservation injury preserved in a hypotermic machine perfusion

Digestive and liver disease, 2008-05, Vol.40 (5), p.A14-A15

2008

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Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism

Cell death and differentiation, 2003-02, Vol.10 (2), p.163-174

2003

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Inefficient coupling between proton transport and ATP synthesis may be the pathogenic mechanism for NARP and Leigh syndrome resulting from the T8993G mutation in mtDNA

Biochemical journal, 2006-05, Vol.395 (3), p.493-500

2006

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The Mitochondrial Production of Reactive Oxygen Species: Mechanisms and Implications in Human Pathology

Is supercomplex organization of the respiratory chain required for optimal electron transfer activity?

Role of Mitochondria in Oxidative Stress and Aging

The primary role of glutathione against nuclear DNA damage of striatum induced by permethrin in rats

The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron–sulfur cluster N2

Role of mitochondria in oxidative stress and ageing

Increased state 4 mitochondrial respiration and swelling in early post-ischemic reperfusion of rat heart

Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone)

Mitochondrial bioenergetics in aging

Rhodamine 123 as a probe of mitochondrial membrane potential: evaluation of proton flux through F 0 during ATP synthesis

Inhibition of glycerophosphate-dependent H2O2 generation in brown fat mitochondria by idebenone

Relevance of mitochondrial genetics and metabolism in cancer development

Hyperoxia fully protects mitochondria of explanted livers

The Role of DT-Diaphorase in the Maintenance of the Reduced Antioxidant Form of Coenzyme Q in Membrane Systems

An Open-Label, Dose-Escalating Phase I Study of Elsamitrucin (SPI 28090) in Treatment of Malignant Solid Tumors in Dogs

The effects of idebenone on mitochondrial bioenergetics

A critical appraisal of the mitochondrial coenzyme Q pool

Biochemical features of mtDNA 14484 (ND6/m64V) point mutation associated with Leber's hereditary optic neuropathy

The mitochondrial respiratory chain is partially organized in a supercomplex assembly: kinetic evidence using flux control analysis

The Mitochondrial Production of Reactive Oxygen Species in Relation to Aging and Pathology

Control of respiration by nitric oxide in Keilin-Hartree particles, mitochondria and SH-SY5Y neuroblastoma cells

Quinone specificity of Complex I

Hyperbaric oxygen reduces rat liver preservation injury preserved in a hypotermic machine perfusion

Apoptosis-resistant phenotype in HL-60-derived cells HCW-2 is related to changes in expression of stress-induced proteins that impact on redox status and mitochondrial metabolism

Inefficient coupling between proton transport and ATP synthesis may be the pathogenic mechanism for NARP and Leigh syndrome resulting from the T8993G mutation in mtDNA

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