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Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells

PloS one, 2016-04, Vol.11 (4), p.e0154303-e0154303

2016

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Expression of human lambda expands the repertoire of OmniChickens

PloS one, 2020-01, Vol.15 (1), p.e0228164-e0228164

2020

Volltextzugriff (PDF)

Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells

Proceedings of the National Academy of Sciences - PNAS, 2013-12, Vol.110 (50), p.20170-20175

2013

Volltextzugriff (PDF)

Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms

PloS one, 2020-07, Vol.15 (7), p.e0235815-e0235815

2020

Volltextzugriff (PDF)

Interspecific germline transmission of cultured primordial germ cells

PloS one, 2012-05, Vol.7 (5), p.e35664-e35664

2012

Volltextzugriff (PDF)

Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire

PloS one, 2013-11, Vol.8 (11), p.e80108-e80108

2013

Volltextzugriff (PDF)

Germline transmission of genetically modified primordial germ cells

Nature, 2006-06, Vol.441 (7094), p.766-769

2006

Volltextzugriff (PDF)

Production of Transgenic Chickens Using Cultured Primordial Germ Cells and Gonocytes

Methods in molecular biology (Clifton, N.J.), 2019, Vol.1874, p.403

2019

Volltextzugriff (PDF)

Expression of heavy chain‐only antibodies can support B‐cell development in light chain knockout chickens

European journal of immunology, 2016-09, Vol.46 (9), p.2137-2148

2016

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Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics

mAbs, 2021-01, Vol.13 (1), p.1862451-1862451

2021

Volltextzugriff (PDF)

A Diverse Repertoire of Human Immunoglobulin Variable Genes in a Chicken B Cell Line is Generated by Both Gene Conversion and Somatic Hypermutation

Frontiers in immunology, 2015-03, Vol.6, p.126-126

2015

Volltextzugriff (PDF)

V(D)J Rearrangement Is Dispensable for Producing CDR-H3 Sequence Diversity in a Gene Converting Species

Frontiers in immunology, 2018-06, Vol.9, p.1317-1317

2018

Volltextzugriff (PDF)

Generation of chickens expressing Cre recombinase

Transgenic research, 2016-10, Vol.25 (5), p.609-616

2016

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Defining brain wiring patterns and mechanisms through gene trapping in mice

Nature (London), 2001-03, Vol.410 (6825), p.174-179

2001

Volltextzugriff (PDF)

Functional analysis of secreted and transmembrane proteins critical to mouse development

Nature genetics, 2001-07, Vol.28 (3), p.241-249

2001

Volltextzugriff (PDF)

Disruption of imprinting caused by deletion of the H19 gene region in mice

Nature (London), 1995-05, Vol.375 (6526), p.34-39

1995

Volltextzugriff (PDF)

Chickens with a Truncated Light Chain Transgene Express Single-Domain H Chain-Only Antibodies

The Journal of immunology (1950), 2024-06, Vol.212 (11), p.1744

2024

Volltextzugriff (PDF)

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets

mAbs, 2018-01, Vol.10 (1), p.71-80

2018

Volltextzugriff (PDF)

The Structural H19 Gene is Required for Transgene Imprinting

Proceedings of the National Academy of Sciences - PNAS, 1996-11, Vol.93 (24), p.13876-13883

1996

Volltextzugriff (PDF)

Production of human monoclonal antibody in eggs of chimeric chickens

Nature biotechnology, 2005-09, Vol.23 (9), p.1159-1169

2005

Volltextzugriff (PDF)

Genetic modification of primordial germ cells by gene trapping, gene targeting, and ϕC31 integrase

Molecular reproduction and development, 2008-07, Vol.75 (7), p.1163-1175

2008

Volltextzugriff (PDF)

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes

Genes & development, 1997-12, Vol.11 (23), p.3128-3142

1997

Volltextzugriff (PDF)

An enhancer deletion affects both H19 and Igf2 expression

Genes & development, 1995-09, Vol.9 (17), p.2079-2089

1995

Volltextzugriff (PDF)

Genetic modification of primordial germ cells by gene trapping, gene targeting, and qC31 integrase

Molecular reproduction and development, 2008-06, Vol.75 (7), p.1163-1175

2008

Volltextzugriff (PDF)

Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire: e80108

PloS one, 2013-11, Vol.8 (11)

2013

Volltextzugriff (PDF)

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Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells

Expression of human lambda expands the repertoire of OmniChickens

Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells

Complementary epitopes and favorable developability of monoclonal anti-LAMP1 antibodies generated using two transgenic animal platforms

Interspecific germline transmission of cultured primordial germ cells

Harnessing gene conversion in chicken B cells to create a human antibody sequence repertoire

Germline transmission of genetically modified primordial germ cells

Production of Transgenic Chickens Using Cultured Primordial Germ Cells and Gonocytes

Expression of heavy chain‐only antibodies can support B‐cell development in light chain knockout chickens

Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics

A Diverse Repertoire of Human Immunoglobulin Variable Genes in a Chicken B Cell Line is Generated by Both Gene Conversion and Somatic Hypermutation

V(D)J Rearrangement Is Dispensable for Producing CDR-H3 Sequence Diversity in a Gene Converting Species

Generation of chickens expressing Cre recombinase

Defining brain wiring patterns and mechanisms through gene trapping in mice

Functional analysis of secreted and transmembrane proteins critical to mouse development

Disruption of imprinting caused by deletion of the H19 gene region in mice

Chickens with a Truncated Light Chain Transgene Express Single-Domain H Chain-Only Antibodies

Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets

The Structural H19 Gene is Required for Transgene Imprinting

Production of human monoclonal antibody in eggs of chimeric chickens

Genetic modification of primordial germ cells by gene trapping, gene targeting, and ϕC31 integrase

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes

An enhancer deletion affects both H19 and Igf2 expression

Genetic modification of primordial germ cells by gene trapping, gene targeting, and qC31 integrase

Harnessing Gene Conversion in Chicken B Cells to Create a Human Antibody Sequence Repertoire: e80108

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