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Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

The Journal of immunology (1950), 2021-01, Vol.206 (2), p.329-334

2021

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High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster

Viruses, 2021-12, Vol.13 (12), p.2506

2021

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Pulmonary infection induces persistent, pathogen-specific lipidomic changes influencing trained immunity

iScience, 2021-09, Vol.24 (9), p.103025-103025, Article 103025

2021

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Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

Nature (London), 2020-09, Vol.585 (7824), p.273-276

2020

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Itaconate deficiency results in prolonged bacterial burdens and enhanced T cell responses during Francisella tularensis infection

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.64-64.17

2021

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Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain

Cellular immunology, 2022-03, Vol.373, p.104485-104485, Article 104485

2022

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Circulating T Cells Are Not Sufficient for Protective Immunity against Virulent Francisella tularensis

The Journal of immunology (1950), 2022-03, Vol.208 (5), p.1180-1188

2022

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Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers

Molecular immunology, 2019-01, Vol.105, p.137-149

2019

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Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators1

The Journal of immunology (1950), 2020-12, Vol.206 (2), p.329-334

2020

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Budget Impact Analysis of a New-Generation Recombinant Factor VIII from a Human Cell Line (Nuwiq) for the Treatment of Patients with Hemophilia A in Canada

Blood, 2017-12, Vol.130, p.4929-4929

2017

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Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation

FEBS letters, 1995-11, Vol.375 (3), p.289-293

1995

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Impact of a physician education and patient awareness campaign on the diagnosis and management of primary immunodeficiencies

Immunologic research, 2008, Vol.40 (1), p.93-94

2008

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The phosphorylation of stathmin by MAP kinase

Molecular and cellular biochemistry, 1993-11, Vol.127-128 (1), p.151-156

1993

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Capsule endoscopy in suspected small bowel Crohn＇s disease： Economic impact of disease diagnosis and treatment

World journal of gastroenterology : WJG, 2009 (45), p.5685-5692

Jonathan A Leighton Ian M Gralnek Randel E Richner Michael J Lacey Frank J Papatheofanis

2009

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Identification of novel phosphorylation sites required for activation of MAPKAP kinase‐2

The EMBO journal, 1995-12, Vol.14 (23), p.5920-5930

1995

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Provincial health services authority online learning calendar and course registration system

Leighton, Ian

2004

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Calculating Risk

Probation journal, 1991-09, Vol.38 (3), p.160-160

Leighton, Ian

1991

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Pulmonary Infection Induces Scarred Lipidome Influencing Trained Immunity

SSRN Electronic Journal

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Pulmonary Infection Induces Persistent, Pathogen-Specific Lipidomic Changes Influencing Trained Immunity

SSRN Electronic Journal

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Cloning and Expression of Cytosolic Phospholipase A 2 (cPLA 2 ) and a Naturally Occurring Variant: Phosphorylation of Ser505 of Recombinant cPLA 2 by p42 Mitogen‐activated Protein Kinase Results in an Increase in Specific Activity

European journal of biochemistry, 1996-06, Vol.238 (3), p.690-697

1996

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Cloning and Expression of Cytosolic Phospholipase A2 (cPLA2) and a Naturally Occurring Variant

European journal of biochemistry, 1996-06, Vol.238 (3), p.690-697

1996

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High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated With Increased COVID-19 Disease Severity and Delayed Recovery in the Syrian Hamster

SSRN Electronic Journal

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Narcotics in Fukien Province, 1918-1930

Leighton, Stewart Ian

1977

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Geography, deer, and host biodiversity shape the pattern of Lyme disease emergence in the Thousand Islands Archipelago of Ontario, Canada

PloS one, 2014-01, Vol.9 (1), p.e85640-e85640

2014

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Genomics and taxonomy in diagnostics for food security: soft-rotting enterobacterial plant pathogens

Analytical methods, 2016-01, Vol.8 (1), p.12-24

2016

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Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators

High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated with Mildly Increased COVID-19 Severity and Delayed Recovery in the Syrian Hamster

Pulmonary infection induces persistent, pathogen-specific lipidomic changes influencing trained immunity

Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2

Itaconate deficiency results in prolonged bacterial burdens and enhanced T cell responses during Francisella tularensis infection

Itaconate indirectly influences expansion of effector T cells following vaccination with Francisella tularensis live vaccine strain

Circulating T Cells Are Not Sufficient for Protective Immunity against Virulent Francisella tularensis

Grainyhead-like-2 confers NK-sensitivity through interactions with epigenetic modifiers

Severe SARS-CoV-2 infection in humans is defined by a shift in the serum lipidome resulting in dysregulation of eicosanoid immune mediators1

Budget Impact Analysis of a New-Generation Recombinant Factor VIII from a Human Cell Line (Nuwiq) for the Treatment of Patients with Hemophilia A in Canada

Comparison of the specificities of p70 S6 kinase and MAPKAP kinase-1 identifies a relatively specific substrate for p70 S6 kinase: the N-terminal kinase domain of MAPKAP kinase-1 is essential for peptide phosphorylation

Impact of a physician education and patient awareness campaign on the diagnosis and management of primary immunodeficiencies

The phosphorylation of stathmin by MAP kinase

Capsule endoscopy in suspected small bowel Crohn＇s disease： Economic impact of disease diagnosis and treatment

Identification of novel phosphorylation sites required for activation of MAPKAP kinase‐2

Provincial health services authority online learning calendar and course registration system

Calculating Risk

Pulmonary Infection Induces Scarred Lipidome Influencing Trained Immunity

Pulmonary Infection Induces Persistent, Pathogen-Specific Lipidomic Changes Influencing Trained Immunity

Cloning and Expression of Cytosolic Phospholipase A 2 (cPLA 2 ) and a Naturally Occurring Variant: Phosphorylation of Ser505 of Recombinant cPLA 2 by p42 Mitogen‐activated Protein Kinase Results in an Increase in Specific Activity

Cloning and Expression of Cytosolic Phospholipase A2 (cPLA2) and a Naturally Occurring Variant

High-Fat High-Sugar Diet-Induced Changes in the Lipid Metabolism Are Associated With Increased COVID-19 Disease Severity and Delayed Recovery in the Syrian Hamster

Narcotics in Fukien Province, 1918-1930

Geography, deer, and host biodiversity shape the pattern of Lyme disease emergence in the Thousand Islands Archipelago of Ontario, Canada

Genomics and taxonomy in diagnostics for food security: soft-rotting enterobacterial plant pathogens

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