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Small Molecules Block the Polymerization of Z α1-Antitrypsin and Increase the Clearance of Intracellular Aggregates

Journal of medicinal chemistry, 2007-11, Vol.50 (22), p.5357-5363

2007

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Extensive compensatory cis-trans regulation in the evolution of mouse gene expression

Genome research, 2012-12, Vol.22 (12), p.2376-2384

2012

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Regulatory Divergence of Transcript Isoforms in a Mammalian Model System

PloS one, 2015-09, Vol.10 (9), p.e0137367-e0137367

2015

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Nuclear transcription factors in mammalian mitochondria

Genome biology, 2010-01, Vol.11 (7), p.215-215

2010

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Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of α1-Antitrypsin: Implications for Disease and Drug Design

Journal of molecular biology, 2009-04, Vol.387 (4), p.857-868

2009

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Regulatory Divergence of Transcript Isoforms in a Mammalian Model System: e0137367

PloS one, 2015-09, Vol.10 (9)

2015

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Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of I- sub(1)-Antitrypsin: Implications for Disease and Drug Design

Journal of molecular biology, 2009-04, Vol.387 (4-3), p.857-868

2009

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The evolution of gene regulation in vertebrates

Leigh-Brown, Sarah Catherine

2012

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Small Molecules Block the Polymerization of Z α 1 -Antitrypsin and Increase the Clearance of Intracellular Aggregates

Journal of medicinal chemistry, 2007-11, Vol.50 (22), p.5357-5363

2007

Volltextzugriff (PDF)

Small molecules block the polymerisation of Z α1-antitrypsin and increase the clearance of intracellular aggregates

Journal of medicinal chemistry, 2007-10, Vol.50 (22), p.5357-5363

2007

Volltextzugriff (PDF)

Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates

Journal of medicinal chemistry, 2007-11, Vol.50 (22), p.5357

2007

Volltextzugriff (PDF)

Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design

Journal of molecular biology, 2009-04, Vol.387 (4), p.857

2009

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Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort

Journal of antimicrobial chemotherapy, 2023-08, Vol.78 (8), p.2000-2007

2023

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Mapping of HIV-1C Transmission Networks Reveals Extensive Spread of Viral Lineages Across Villages in Botswana Treatment-as-Prevention Trial

The Journal of infectious diseases, 2020-11, Vol.222 (10), p.1670-1680

2020

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Inferring the multiplicity of founder variants initiating HIV-1 infection: a systematic review and individual patient data meta-analysis

The Lancet. Microbe, 2023-02, Vol.4 (2), p.e102-e112

2023

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Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic

Scientific reports, 2016-12, Vol.6 (1), p.39489-39489, Article 39489

2016

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Epidemiology of non-B clade forms of HIV-1 in men who have sex with men in the UK

AIDS (London), 2010-09, Vol.24 (15), p.2397-2401

2010

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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

Science translational medicine, 2024-02, Vol.16 (734), p.eadg7162

2024

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The prevalence of darunavir―associated mutations in HIV―1―infected children in the UK

Antiviral therapy, 2012-01, Vol.17 (4), p.599-603

2012

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Mismatched human leukocyte antigen alleles protect against heterosexual HIV transmission

Journal of acquired immune deficiency syndromes (1999), 2001-07, Vol.27 (3), p.277-280

2001

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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature (London), 2022-03, Vol.603 (7899), p.131-137

2022

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Associations between baseline characteristics, CD4 cell count response and virological failure on first-line efavirenz + tenofovir + emtricitabine for HIV

Journal of Virus Eradication, 2019-11, Vol.5 (4), p.204-211

2019

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Developing biomarkers of TDP‐43‐related splicing dysfunction in frontotemporal dementia

Alzheimer's & dementia, 2021-12, Vol.17 (S4), p.n/a

2021

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Evidence of a decline in transmitted HIV-1 drug resistance in the united Kingdom

AIDS (London), 2007-05, Vol.21 (8), p.1035-1039

Dunn, D

2007

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Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Nature (London), 2024-07, Vol.631 (8020), p.E7-E7

2024

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Small Molecules Block the Polymerization of Z α1-Antitrypsin and Increase the Clearance of Intracellular Aggregates

Extensive compensatory cis-trans regulation in the evolution of mouse gene expression

Regulatory Divergence of Transcript Isoforms in a Mammalian Model System

Nuclear transcription factors in mammalian mitochondria

Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of α1-Antitrypsin: Implications for Disease and Drug Design

Regulatory Divergence of Transcript Isoforms in a Mammalian Model System: e0137367

Crystallographic and Cellular Characterisation of Two Mechanisms Stabilising the Native Fold of I- sub(1)-Antitrypsin: Implications for Disease and Drug Design

The evolution of gene regulation in vertebrates

Small Molecules Block the Polymerization of Z α 1 -Antitrypsin and Increase the Clearance of Intracellular Aggregates

Small molecules block the polymerisation of Z α1-antitrypsin and increase the clearance of intracellular aggregates

Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates

Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design

Limited emergence of resistance to integrase strand transfer inhibitors (INSTIs) in ART-experienced participants failing dolutegravir-based antiretroviral therapy: a cross-sectional analysis of a Northeast Nigerian cohort

Mapping of HIV-1C Transmission Networks Reveals Extensive Spread of Viral Lineages Across Villages in Botswana Treatment-as-Prevention Trial

Inferring the multiplicity of founder variants initiating HIV-1 infection: a systematic review and individual patient data meta-analysis

Using nearly full-genome HIV sequence data improves phylogeny reconstruction in a simulated epidemic

Epidemiology of non-B clade forms of HIV-1 in men who have sex with men in the UK

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

The prevalence of darunavir―associated mutations in HIV―1―infected children in the UK

Mismatched human leukocyte antigen alleles protect against heterosexual HIV transmission

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

Associations between baseline characteristics, CD4 cell count response and virological failure on first-line efavirenz + tenofovir + emtricitabine for HIV

Developing biomarkers of TDP‐43‐related splicing dysfunction in frontotemporal dementia

Evidence of a decline in transmitted HIV-1 drug resistance in the united Kingdom

Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A

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