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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex

Nature (London), 2018-03, Vol.555 (7694), p.121-125

2018

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Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation

Science signaling, 2021-10, Vol.14 (703), p.eabc5944

2021

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Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction

Ecotoxicology and environmental safety, 2023-11, Vol.266, p.115605-115605, Article 115605

2023

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Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation

Nature chemical biology, 2020-10, Vol.16 (10), p.1096-1104

2020

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Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism

The Journal of biological chemistry, 2018-06, Vol.293 (24), p.9370-9387

2018

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Clinical perspectives of isoniazid-induced liver injury

Liver research, 2021-06, Vol.5 (2), p.45-52

2021

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Precise druggability of the PTH type 1 receptor

Nature chemical biology, 2022-03, Vol.18 (3), p.272-280

2022

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Iron metabolism mediates the relationship between Vitamin C and hepatic steatosis and fibrosis in NAFLD

Frontiers in nutrition (Lausanne), 2022-09, Vol.9, p.952056-952056

2022

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Activation of PXR causes drug interactions with Paxlovid in transgenic mice

Acta pharmaceutica Sinica. B, 2023-11, Vol.13 (11), p.4502-4510

2023

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PPARγ Regulates Triclosan Induced Placental Dysfunction

Cells (Basel, Switzerland), 2021-12, Vol.11 (1), p.86

2021

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PFOS Inhibited Normal Functional Development of Placenta Cells via PPARγ Signaling

Biomedicines, 2021-06, Vol.9 (6), p.677

2021

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Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice)

Liver research, 2022-12, Vol.6 (4), p.251-257

2022

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Application of chemical biology in target identification and drug discovery

Archives of Pharmacal Research, 2015, 38(9), , pp.1642-1650

2015

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Identification of PXR Activators from Uncaria Rhynchophylla (Gou Teng) and Uncaria Tomentosa (Cat's Claw)

Drug metabolism and disposition, 2023-05, Vol.51 (5), p.629-636

2023

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LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3

Environmental pollution (1987), 2022-01, Vol.293, p.118542-118542, Article 118542

2022

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Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity

Chemical research in toxicology, 2021-12, Vol.34 (12), p.2534-2539

2021

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Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signaling

European journal of pharmacology, 2024-04, Vol.968, p.176419-176419, Article 176419

2024

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Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors

European journal of medicinal chemistry, 2023-11, Vol.259, p.115666-115666, Article 115666

2023

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Precision druggability of a class B GPCR, the PTH type 1 receptor

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.03186

2021

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G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells

Oncotarget, 2016-03, Vol.7 (11), p.12823-12839

2016

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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptorGs complex

Nature (London), 2018-03, Vol.555 (7694), p.121

2018

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Experimental Characterization and Microstructural Evaluation of Silicon Bronze-Alloy Steel Bimetallic Structures by Additive Manufacturing

Metallurgical and materials transactions. A, Physical metallurgy and materials science, 2021-10, Vol.52 (10), p.4664-4674

2021

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Apigenin intervenes in liver fibrosis by regulating PKM2-HIF-1α mediated oxidative stress

Biochemical and biophysical research communications, 2024-08, Vol.721, p.150130-150130, Article 150130

2024

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Highly efficient photocatalytic reduction of nitrogen into ammonia by single Ru atom catalyst supported by BeO monolayer

Chinese chemical letters, 2022-01, Vol.33 (1), p.399-403

2022

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Evolution of grain boundary α phase during cooling from β phase field in a α + β titanium alloy

Materials letters, 2021-10, Vol.301, p.130318, Article 130318

2021

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Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor-Gs complex

Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation

Activation of LXRα attenuates 2-Ethylhexyl diphenyl phosphate (EHDPP) induced placental dysfunction

Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation

Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism

Clinical perspectives of isoniazid-induced liver injury

Precise druggability of the PTH type 1 receptor

Iron metabolism mediates the relationship between Vitamin C and hepatic steatosis and fibrosis in NAFLD

Activation of PXR causes drug interactions with Paxlovid in transgenic mice

PPARγ Regulates Triclosan Induced Placental Dysfunction

PFOS Inhibited Normal Functional Development of Placenta Cells via PPARγ Signaling

Chemical basis of pregnane X receptor activators in the herbal supplement Gancao (licorice)

Application of chemical biology in target identification and drug discovery

Identification of PXR Activators from Uncaria Rhynchophylla (Gou Teng) and Uncaria Tomentosa (Cat's Claw)

LncRNA MEG3 alleviates PFOS induced placental cell growth inhibition through its derived miR-770 targeting PTX3

Role of CYP2A6 in Methimazole Bioactivation and Hepatotoxicity

Distinct roles of the extracellular surface residues of glucagon-like peptide-1 receptor in β-arrestin 1/2 signaling

Metabolism-guided development of Ko143 analogs as ABCG2 inhibitors

Precision druggability of a class B GPCR, the PTH type 1 receptor

G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells

Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptorGs complex

Experimental Characterization and Microstructural Evaluation of Silicon Bronze-Alloy Steel Bimetallic Structures by Additive Manufacturing

Apigenin intervenes in liver fibrosis by regulating PKM2-HIF-1α mediated oxidative stress

Highly efficient photocatalytic reduction of nitrogen into ammonia by single Ru atom catalyst supported by BeO monolayer

Evolution of grain boundary α phase during cooling from β phase field in a α + β titanium alloy

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