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Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

Amino acids, 2015-03, Vol.47 (3), p.603-615

2015

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Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease

Toxicology and applied pharmacology, 2013-04, Vol.268 (2), p.132-140

2013

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Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model

Obesity (Silver Spring, Md.), 2017-06, Vol.25 (6), p.1069-1076

2017

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Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice

PloS one, 2012-04, Vol.7 (4), p.e34522

2012

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Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease

Digestive diseases and sciences, 2014-02, Vol.59 (2), p.365-374

2014

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Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism

Biochemical pharmacology, 2013-08, Vol.86 (3), p.437-445

2013

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Image gently campaign back to basics initiative: ten steps to help manage radiation dose in pediatric digital radiography

American journal of roentgenology (1976), 2013-05, Vol.200 (5), p.W431

2013

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Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2

Drug metabolism and disposition, 2007-06, Vol.35 (6), p.995

2007

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Characterization of Organic Anion-Transporting Polypeptide (Oatp) 1a1 and 1a4 Null Mice Reveals Altered Transport Function and Urinary Metabolomic Profiles

Toxicological sciences, 2011-08, Vol.122 (2), p.587-597

2011

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Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury

Toxicological sciences, 2012-06, Vol.127 (2), p.451-462

2012

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A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action

Critical reviews in toxicology, 2003-01, Vol.33 (6), p.591-653

2003

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Loss of Organic Anion Transporting Polypeptide 1a1 Increases Deoxycholic Acid Absorption in Mice by Increasing Intestinal Permeability

Toxicological sciences, 2011-12, Vol.124 (2), p.251-260

2011

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The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling

BMC genomics, 2013-08, Vol.14 (1), p.575-575, Article 575

2013

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Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice

Toxicology and applied pharmacology, 2011-11, Vol.257 (1), p.23-31

2011

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Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein

Frontiers in pharmacology, 2022-06, Vol.13, p.829063-829063

2022

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Identification of 1- and 3-methylhistidine as biomarkers of skeletal muscle toxicity by nuclear magnetic resonance-based metabolic profiling

Analytical biochemistry, 2011-03, Vol.410 (1), p.84-91

2011

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Metabolic Detoxification Determines Species Differences in Coumarin-Induced Hepatotoxicity

Toxicological sciences, 2004-08, Vol.80 (2), p.249-257

2004

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Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

Toxicology and applied pharmacology, 2003-03, Vol.187 (3), p.137-146

2003

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Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example

International journal of molecular sciences, 2010-11, Vol.11 (11), p.4697-4714

2010

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Bicyclic Ligand-Biased Agonists of S1P1: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles

Journal of medicinal chemistry, 2021-02, Vol.64 (3), p.1454-1480

2021

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Bicyclic Ligand-Biased Agonists of S1P 1 : Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles

Journal of medicinal chemistry, 2021-02, Vol.64 (3), p.1454-1480

2021

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Identification and Preclinical Pharmacology of ((1R,3S)‑1-Amino-3-((S)‑6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical Trials

Journal of medicinal chemistry, 2019-03, Vol.62 (5), p.2265-2285

2019

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Establishment of a molecular embryonic stem cell developmental toxicity assay

Toxicological sciences, 2013-02, Vol.131 (2), p.447-457

2013

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Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine

The Journal of pharmacology and experimental therapeutics, 2006-05, Vol.317 (2), p.635

2006

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Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P1) Modulators: Optimization of the PK, PD, and Safety Profiles

ACS medicinal chemistry letters, 2020-09, Vol.11 (9), p.1766-1772

2020

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Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease

Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model

Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice

Characterization of Hepatocellular Carcinoma Related Genes and Metabolites in Human Nonalcoholic Fatty Liver Disease

Organic anion-transporting polypeptide 1a4 (Oatp1a4) is important for secondary bile acid metabolism

Image gently campaign back to basics initiative: ten steps to help manage radiation dose in pediatric digital radiography

Induction of drug-metabolizing enzymes by garlic and allyl sulfide compounds via activation of constitutive androstane receptor and nuclear factor E2-related factor 2

Characterization of Organic Anion-Transporting Polypeptide (Oatp) 1a1 and 1a4 Null Mice Reveals Altered Transport Function and Urinary Metabolomic Profiles

Organic anion transporting polypeptide 1a1 null mice are sensitive to cholestatic liver injury

A Framework for Human Relevance Analysis of Information on Carcinogenic Modes of Action

Loss of Organic Anion Transporting Polypeptide 1a1 Increases Deoxycholic Acid Absorption in Mice by Increasing Intestinal Permeability

The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling

Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice

Application of Pharmacokinetic/Pharmacodynamic Modeling to Bridge Mouse Antitumor Efficacy and Monkey Toxicology Data for Determining the Therapeutic Index of an Interleukin-10 Fc Fusion Protein

Identification of 1- and 3-methylhistidine as biomarkers of skeletal muscle toxicity by nuclear magnetic resonance-based metabolic profiling

Metabolic Detoxification Determines Species Differences in Coumarin-Induced Hepatotoxicity

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

Comparison of TNFα to lipopolysaccharide as an inflammagen to characterize the idiosyncratic hepatotoxicity potential of drugs: Trovafloxacin as an example

Bicyclic Ligand-Biased Agonists of S1P1: Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles

Bicyclic Ligand-Biased Agonists of S1P 1 : Exploring Side Chain Modifications to Modulate the PK, PD, and Safety Profiles

Identification and Preclinical Pharmacology of ((1R,3S)‑1-Amino-3-((S)‑6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986166): A Differentiated Sphingosine-1-phosphate Receptor 1 (S1P1) Modulator Advanced into Clinical Trials

Establishment of a molecular embryonic stem cell developmental toxicity assay

Coagulation-dependent gene expression and liver injury in rats given lipopolysaccharide with ranitidine but not with famotidine

Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P1) Modulators: Optimization of the PK, PD, and Safety Profiles

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