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The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (12), p.3987-4006

2006

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Recent advances in the synthesis of purine derivatives and their precursors

Tetrahedron, 2008-09, Vol.64 (37), p.8585-8603

Legraverend, Michel

2008

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Synthesis and evaluation of spectroscopic properties of newly synthesized push–pull 6-amino-8-styryl purines

Dyes and pigments, 2014-06, Vol.105, p.145-151

2014

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Microwave-Assisted Pd/Cu-Catalyzed C-8 Direct Alkenylation of Purines and Related Azoles: An Alternative Access to 6,8,9-Trisubstituted Purines

Journal of organic chemistry, 2011-11, Vol.76 (22), p.9542-9547

2011

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Inhibitors of the TAM subfamily of tyrosine kinases: Synthesis and biological evaluation

European journal of medicinal chemistry, 2013-03, Vol.61, p.2-25

2013

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Palladium-Catalyzed Amidation and Amination of 8-Iodopurine

European journal of organic chemistry, 2012-05, Vol.2012 (15), p.2889-2893

2012

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Synthesis of 6,7,8-Trisubstituted Purines via a Copper-Catalyzed Amidation Reaction

Journal of organic chemistry, 2009-01, Vol.74 (1), p.463-465

2009

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Regioselective Sonogashira cross-coupling reactions of 6-chloro-2,8-diiodo-9-THP-9H-purine with alkyne derivatives

Tetrahedron letters, 2011-01, Vol.52 (2), p.305-307

2011

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Selective Amidation of 2,6-Dihalogenopurines: Application to the Synthesis of New 2,6,9-Trisubstituted Purines

Journal of organic chemistry, 2007-08, Vol.72 (18), p.7026-7029

2007

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Novel 8-arylated purines as inhibitors of glycogen synthase kinase

European journal of medicinal chemistry, 2010-08, Vol.45 (8), p.3389-3393

2010

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Palladium-Catalyzed Cross-Coupling between 8-Substituted 6-Thiophenylpurines and Boronic Acids

Synthesis (Stuttgart), 2014-04, Vol.46 (7), p.933-942

2014

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New aminopyrimidine derivatives as inhibitors of the TAM family

European journal of medicinal chemistry, 2013-12, Vol.70, p.789-801

2013

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Yeast as a model system to screen purine derivatives against human CDK1 and CDK2 kinases

Journal of biotechnology, 2015-02, Vol.195, p.30-36

2015

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Traceless solid-phase synthesis of 2,6,9-trisubstituted purines from resin bound 6-thiopurines

Tetrahedron, 2002-09, Vol.58 (39), p.7911-7923

2002

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Cyclin-dependent kinase (CDK) inhibitors: development of a general strategy for the construction of 2,6,9-trisubstituted purine libraries. Part 1

Tetrahedron letters, 2001-11, Vol.42 (46), p.8161-8164

2001

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Targeting the cell cycle and the PI3K pathway: A possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells

International journal of oncology, 2010-04, Vol.36 (4), p.873-881

2010

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Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors

Bioorganic & medicinal chemistry letters, 2006-06, Vol.16 (12), p.3144-3146

2006

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Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

Journal of medicinal chemistry, 2000-04, Vol.43 (7), p.1282-1292

2000

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3D-QSAR CoMFA on Cyclin-Dependent Kinase Inhibitors

Journal of medicinal chemistry, 2000-11, Vol.43 (22), p.4098-4108

2000

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Cyclin-dependent kinase (CDK) inhibitors: development of a general strategy for the construction of 2,6,9-trisubstituted purine libraries. Part 3

Tetrahedron letters, 2001-11, Vol.42 (46), p.8169-8171

2001

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Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Bioorganic & medicinal chemistry, 1999-07, Vol.7 (7), p.1281-1293

1999

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Cyclin-dependent kinase (CDK) inhibitors: development of a general strategy for the construction of 2,6,9-trisubstituted purine libraries. Part 2

Tetrahedron letters, 2001-11, Vol.42 (46), p.8165-8167

2001

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Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

Bioorganic & medicinal chemistry letters, 1998-04, Vol.8 (7), p.793-798

1998

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Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

Journal of medicinal chemistry, 2000-10, Vol.43 (21), p.3949-3962

2000

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ChemInform Abstract: Recent Advances in the Synthesis of Purine Derivatives and Their Precursors

ChemInform, 2008-11, Vol.39 (47), p.no-no

Legraverend, Michel

2008

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The purines: Potent and versatile small molecule inhibitors and modulators of key biological targets

Recent advances in the synthesis of purine derivatives and their precursors

Synthesis and evaluation of spectroscopic properties of newly synthesized push–pull 6-amino-8-styryl purines

Microwave-Assisted Pd/Cu-Catalyzed C-8 Direct Alkenylation of Purines and Related Azoles: An Alternative Access to 6,8,9-Trisubstituted Purines

Inhibitors of the TAM subfamily of tyrosine kinases: Synthesis and biological evaluation

Palladium-Catalyzed Amidation and Amination of 8-Iodopurine

Synthesis of 6,7,8-Trisubstituted Purines via a Copper-Catalyzed Amidation Reaction

Regioselective Sonogashira cross-coupling reactions of 6-chloro-2,8-diiodo-9-THP-9H-purine with alkyne derivatives

Selective Amidation of 2,6-Dihalogenopurines: Application to the Synthesis of New 2,6,9-Trisubstituted Purines

Novel 8-arylated purines as inhibitors of glycogen synthase kinase

Palladium-Catalyzed Cross-Coupling between 8-Substituted 6-Thiophenylpurines and Boronic Acids

New aminopyrimidine derivatives as inhibitors of the TAM family

Yeast as a model system to screen purine derivatives against human CDK1 and CDK2 kinases

Traceless solid-phase synthesis of 2,6,9-trisubstituted purines from resin bound 6-thiopurines

Cyclin-dependent kinase (CDK) inhibitors: development of a general strategy for the construction of 2,6,9-trisubstituted purine libraries. Part 1

Targeting the cell cycle and the PI3K pathway: A possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells

Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors

Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

3D-QSAR CoMFA on Cyclin-Dependent Kinase Inhibitors

Cyclin-dependent kinase (CDK) inhibitors: development of a general strategy for the construction of 2,6,9-trisubstituted purine libraries. Part 3

Synthesis and in vitro evaluation of novel 2,6,9-trisubstituted purines acting as cyclin-dependent kinase inhibitors

Cyclin-dependent kinase (CDK) inhibitors: development of a general strategy for the construction of 2,6,9-trisubstituted purine libraries. Part 2

Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

Synthesis and Antiviral Activity of 4-Benzyl Pyridinone Derivatives as Potent and Selective Non-Nucleoside Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors

ChemInform Abstract: Recent Advances in the Synthesis of Purine Derivatives and Their Precursors

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