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Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Archives of toxicology, 2021-01, Vol.95 (1), p.311-319

2021

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Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

Archives of toxicology, 2022-02, Vol.96 (2), p.511-524

2022

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Relationship between N-acetyltransferase 2 single-nucleotide polymorphisms and phenotype

Carcinogenesis (New York), 2010-02, Vol.31 (2), p.326-327

2010

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High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors

SLAS discovery, 2017-07, Vol.22 (6), p.686-695

2017

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Identification and Characterization of Novel Arylamine NAcetyltransferase Small Molecule Inhibitors

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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Development of a Nicotinic Acetylcholine Receptor nAChR α7 Binding Activity Prediction Model

Journal of chemical information and modeling, 2020-04, Vol.60 (4), p.2396-2404

2020

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Smoke Chemistry, In Vitro Cytotoxicity, and Genotoxicity Demonstrates Enhanced Toxicity of Cigarillos Compared With Cigarettes

Toxicological sciences, 2021-02, Vol.180 (1), p.122-135

2021

Volltextzugriff (PDF)

Biomarkers of Exposure among Adult Smokeless Tobacco Users in the Population Assessment of Tobacco and Health Study (Wave 1, 2013-2014)

Cancer epidemiology, biomarkers & prevention, 2020-03, Vol.29 (3), p.659-667

2020

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Competitive docking model for prediction of the human nicotinic acetylcholine receptor α7 binding of tobacco constituents

Oncotarget, 2018-03, Vol.9 (24), p.16899-16916

2018

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Synthesis of [ 11C]SSR149415 and preliminary imaging studies using positron emission tomography

Bioorganic & medicinal chemistry letters, 2010-05, Vol.20 (10), p.3103-3106

2010

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Role of human arylamine N-acetyltransferase in carcinogen metabolism and human breast cancer progression

Leggett, Carmine Simone

2012

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Development of Nicotinic Acetylcholine Receptor nAChR α7 Binding Activity Prediction Model: Coupling Machine Learning with Competitive Molecular Docking

Proceedings of the 8th ACM International Conference on Bioinformatics, Computational Biology,and Health Informatics, 2017, p.584-584

2017

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Functional effect of CYP1A2, NAT1, and NAT2 genetic variants in nucleotide excision repair - deficient human fibroblasts: Implications for toxicological risk from environmental arylamines

Leggett, Carmine Simone

2010

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Acetylation of putative arylamine and alkylaniline carcinogens in immortalized human fibroblasts transfected with rapid and slow acetylator N-acetyltransferase 2 haplotypes

Identification and characterization of potent, selective, and efficacious inhibitors of human arylamine N-acetyltransferase 1

Relationship between N-acetyltransferase 2 single-nucleotide polymorphisms and phenotype

High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors

Identification and Characterization of Novel Arylamine NAcetyltransferase Small Molecule Inhibitors

Development of a Nicotinic Acetylcholine Receptor nAChR α7 Binding Activity Prediction Model

Smoke Chemistry, In Vitro Cytotoxicity, and Genotoxicity Demonstrates Enhanced Toxicity of Cigarillos Compared With Cigarettes

Biomarkers of Exposure among Adult Smokeless Tobacco Users in the Population Assessment of Tobacco and Health Study (Wave 1, 2013-2014)

Competitive docking model for prediction of the human nicotinic acetylcholine receptor α7 binding of tobacco constituents

Synthesis of [ 11C]SSR149415 and preliminary imaging studies using positron emission tomography

Role of human arylamine N-acetyltransferase in carcinogen metabolism and human breast cancer progression

Development of Nicotinic Acetylcholine Receptor nAChR α7 Binding Activity Prediction Model: Coupling Machine Learning with Competitive Molecular Docking

Functional effect of CYP1A2, NAT1, and NAT2 genetic variants in nucleotide excision repair - deficient human fibroblasts: Implications for toxicological risk from environmental arylamines

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