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Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia

Leukemia, 2021-11, Vol.35 (11), p.3188-3200

2021

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Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy

Molecular and Cellular Biology, 2004-09, Vol.24 (17), p.7612-7621

2004

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Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

The Journal of biological chemistry, 2004-05, Vol.279 (21), p.22250-22257

2004

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Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice

Cancer research (Chicago, Ill.), 2004-10, Vol.64 (20), p.7491-7499

2004

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Topotecan Combination Chemotherapy in Two New Rodent Models of Retinoblastoma

Clinical cancer research, 2005-10, Vol.11 (20), p.7569-7578

2005

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Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates

JCO clinical cancer informatics, 2017-11, Vol.1 (1), p.1-12

2017

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Metabolism and transport pathways of the blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10-hydroxycamptothecin)

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.2553-2553

2009

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Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats

Drug metabolism and disposition, 2006-04, Vol.34 (4), p.653-659

2006

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Microbore HPLC method with online microdialysis for measurement of topotecan lactone and carboxylate in murine CSF

Journal of pharmaceutical sciences, 2004-09, Vol.93 (9), p.2284-2295

2004

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Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-11, Vol.844 (1), p.15-22

2006

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Clinical and pharmacokinetic (PK) findings in a phase I study of 7-t-butyldimethylsilyl-10-hydroxycamptothecin (AR-67) in patients with refractory solid tumors

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.2534-2534

2009

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Pharmacokinetics (PK) of the highly lipophilic and blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10- hydroxycamptothecin) in adult patients with solid malignancies

Journal of clinical oncology, 2009-05, Vol.27 (15_suppl), p.2546-2546

2009

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Effects of dexamethasone (Dex) pretreatment on toxicity and efficacy of carboplatin and gemcitabine (Carbo/Gem) in patients with non-small cell lung cancer (NSCLC)

Journal of clinical oncology, 2007-06, Vol.25 (18_suppl), p.18124-18124

2007

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Immunohistochemical Detection of Multidrug-Resistant Protein Expression in Retinoblastoma Treated by Primary Enucleation

Investigative ophthalmology & visual science, 2006-04, Vol.47 (4), p.1269-1273

2006

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Relation between Irofulven (MGI-114) Systemic Exposure and Tumor Response in Human Solid Tumor Xenografts

Clinical cancer research, 2002-09, Vol.8 (9), p.3000-3007

2002

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Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia

PloS one, 2019-02, Vol.14 (2), p.e0211910

2019

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Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs

PloS one, 2018-11, Vol.13 (11), p.e0206279-e0206279

2018

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Development of a physiologically based model to describe the pharmacokinetics of methylphenidate in juvenile and adult humans and nonhuman primates

PloS one, 2014-09, Vol.9 (9), p.e106101

2014

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Characterizing cell motions in flowing blood

Proceedings of the First Joint BMES/EMBS Conference : serving humanity advancing technology, Oct. 13-16, 99, Atlanta, GA, USA, 1999, Vol.1, p.43 vol.1-43

1999

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Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

Clinical and translational science, 2021-07, Vol.14 (4), p.1231-1249

2021

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Clonidine as Monotherapy for Neonatal Opioid Withdrawal Syndrome: A Randomized Trial

Pediatrics (Evanston), 2024-11, Vol.154 (5)

2024

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A pilot clinical study of oral irinotecan HCl (VAL-413) in patients with recurrent pediatric solid tumors

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.TPS10073-TPS10073

2023

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Neonatal Abstinence Signs during Treatment: Trajectory, Resurgence and Heterogeneity

Children (Basel), 2024-02, Vol.11 (2), p.203

2024

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Assessment of the relative clinical utility of shortened Finnegan neonatal abstinence scoring tools

Journal of perinatology, 2022-08, Vol.42 (8), p.1051-1057

2022

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A pilot clinical study of VAL-413 (oral irinotecan HCl) in patients with recurrent pediatric solid tumors

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.TPS10063-TPS10063

2022

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Interleukin-10 suppression enhances T-cell antitumor immunity and responses to checkpoint blockade in chronic lymphocytic leukemia

Mrp4 Confers Resistance to Topotecan and Protects the Brain from Chemotherapy

Interactions between Hepatic Mrp4 and Sult2a as Revealed by the Constitutive Androstane Receptor and Mrp4 Knockout Mice

Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice

Topotecan Combination Chemotherapy in Two New Rodent Models of Retinoblastoma

Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates

Metabolism and transport pathways of the blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10-hydroxycamptothecin)

Dependence of nelfinavir brain uptake on dose and tissue concentrations of the selective P-glycoprotein inhibitor zosuquidar in rats

Microbore HPLC method with online microdialysis for measurement of topotecan lactone and carboxylate in murine CSF

Validation of an HPLC method for analysis of DB-67 and its water soluble prodrug in mouse plasma

Clinical and pharmacokinetic (PK) findings in a phase I study of 7-t-butyldimethylsilyl-10-hydroxycamptothecin (AR-67) in patients with refractory solid tumors

Pharmacokinetics (PK) of the highly lipophilic and blood stable camptothecin AR-67 (7-t-butyldimethylsilyl-10- hydroxycamptothecin) in adult patients with solid malignancies

Effects of dexamethasone (Dex) pretreatment on toxicity and efficacy of carboplatin and gemcitabine (Carbo/Gem) in patients with non-small cell lung cancer (NSCLC)

Immunohistochemical Detection of Multidrug-Resistant Protein Expression in Retinoblastoma Treated by Primary Enucleation

Relation between Irofulven (MGI-114) Systemic Exposure and Tumor Response in Human Solid Tumor Xenografts

Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia

Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugs

Development of a physiologically based model to describe the pharmacokinetics of methylphenidate in juvenile and adult humans and nonhuman primates

Characterizing cell motions in flowing blood

Clinical pharmacology and dosing regimen optimization of neonatal opioid withdrawal syndrome treatments

Clonidine as Monotherapy for Neonatal Opioid Withdrawal Syndrome: A Randomized Trial

A pilot clinical study of oral irinotecan HCl (VAL-413) in patients with recurrent pediatric solid tumors

Neonatal Abstinence Signs during Treatment: Trajectory, Resurgence and Heterogeneity

Assessment of the relative clinical utility of shortened Finnegan neonatal abstinence scoring tools

A pilot clinical study of VAL-413 (oral irinotecan HCl) in patients with recurrent pediatric solid tumors

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