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Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

Journal of medicinal chemistry, 2000-10, Vol.43 (20), p.3587-3595

2000

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Small molecule p38 inhibitors: novel structural features and advances from 2002-2005

Current topics in medicinal chemistry, 2005-09, Vol.5 (10), p.967-985

2005

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5-Cyanopyrimidine Derivatives as a Novel Class of Potent, Selective, and Orally Active Inhibitors of p38α MAP Kinase

Journal of medicinal chemistry, 2005-10, Vol.48 (20), p.6261-6270

2005

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N-Amination of Pyrrole and Indole Heterocycles with Monochloramine (NH2Cl)

Journal of organic chemistry, 2004-02, Vol.69 (4), p.1368-1371

2004

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The Discovery of Orally Active Triaminotriazine Aniline Amides as Inhibitors of p38 MAP Kinase

Journal of medicinal chemistry, 2004-12, Vol.47 (25), p.6283-6291

2004

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Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties

Journal of medicinal chemistry, 2003-05, Vol.46 (11), p.2110-2116

2003

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Identification of purine inhibitors of phosphodiesterase 7 (PDE7)

Bioorganic & medicinal chemistry letters, 2004-06, Vol.14 (11), p.2955-2958

2004

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Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor

Oncogene, 1994-08, Vol.9 (8), p.2405-2413

1994

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Potent, Cell Active, Non-Thiol Tetrapeptide Inhibitors of Farnesyltransferase

Journal of medicinal chemistry, 1996-01, Vol.39 (2), p.353-358

1996

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C-3 Amido-Indole cannabinoid receptor modulators

Bioorganic & medicinal chemistry letters, 2002-09, Vol.12 (17), p.2399-2402

2002

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Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (20), p.2931-2934

2002

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Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5241-5253

1999

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Molecular structural requirements for binding and activation of L-alanine taste receptors

Amino acids, 1993-02, Vol.4 (1-2), p.73-88

1993

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Peptide based P21RAS farnesyl transferase inhibitors : systematic modification of the tetrapeptide CA1A2X motif

Bioorganic & medicinal chemistry letters, 1994, Vol.4 (7), p.887-892

1994

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Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and in Vivo Activity

Journal of medicinal chemistry, 1996-01, Vol.39 (1), p.224-236

1996

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A General Large Scale Synthesis of 2-Alkyl-7-methoxyindoles

Heterocycles, 2001-05, Vol.55 (5), p.951

2001

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Synthesis and .beta.-adrenergic antagonist activity of stereoisomeric practolol and propranolol derivatives

Journal of medicinal chemistry, 1990-01, Vol.33 (1), p.216-223

1990

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Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5288-5288

1999

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A Facile Synthesis of (S)-3-Tosyloxy-1,2-propanediol from (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol

Synthesis (Stuttgart), 1989, Vol.1989 (7), p.564-565

1989

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Structure/activity relationships in the L-alanine taste receptor system of the channel catfish, Ictalurus punctatus

Physiology & behavior, 1991-05, Vol.49 (5), p.891-898

1991

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Peptide based P21 RAS farnesyl transferase inhibitors: systematic modification of the tetrapeptide CA 1A 2X motif

Bioorganic & medicinal chemistry letters, 1994, Vol.4 (7), p.887-892

1994

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ChemInform Abstract: Synthesis and β‐Adrenergic Antagonist Activity of Stereoisomeric Practolol and Propranolol Derivatives

ChemInform, 1990-05, Vol.21 (22), p.no-no

1990

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ChemInform Abstract: A Facile Synthesis of (S)‐3‐Tosyloxy‐1,2‐propanediol (V) from (S)‐2,2‐Dimethyl‐1,3‐dioxolane‐4‐methanol (I)

ChemInform, 1989-12, Vol.20 (51), p.no-no

1989

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Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI)

Journal of medicinal chemistry, 2023-03, Vol.66 (6), p.3651-3655

2023

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Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI)

ACS medicinal chemistry letters, 2023-04, Vol.14 (4), p.345-349

2023

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Discovery of (R)-7-Cyano-2,3,4,5-tetrahydro-1-(1H-imidazol-4-ylmethyl)-3- (phenylmethyl)-4-(2-thienylsulfonyl)-1H-1,4-benzodiazepine (BMS-214662), a Farnesyltransferase Inhibitor with Potent Preclinical Antitumor Activity

Small molecule p38 inhibitors: novel structural features and advances from 2002-2005

5-Cyanopyrimidine Derivatives as a Novel Class of Potent, Selective, and Orally Active Inhibitors of p38α MAP Kinase

N-Amination of Pyrrole and Indole Heterocycles with Monochloramine (NH2Cl)

The Discovery of Orally Active Triaminotriazine Aniline Amides as Inhibitors of p38 MAP Kinase

Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties

Identification of purine inhibitors of phosphodiesterase 7 (PDE7)

Vav cooperates with Ras to transform rodent fibroblasts but is not a Ras GDP/GTP exchange factor

Potent, Cell Active, Non-Thiol Tetrapeptide Inhibitors of Farnesyltransferase

C-3 Amido-Indole cannabinoid receptor modulators

Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase

Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

Molecular structural requirements for binding and activation of L-alanine taste receptors

Peptide based P21RAS farnesyl transferase inhibitors : systematic modification of the tetrapeptide CA1A2X motif

Development of Highly Potent Inhibitors of Ras Farnesyltransferase Possessing Cellular and in Vivo Activity

A General Large Scale Synthesis of 2-Alkyl-7-methoxyindoles

Synthesis and .beta.-adrenergic antagonist activity of stereoisomeric practolol and propranolol derivatives

Discovery and Structure−Activity Relationships of Imidazole-Containing Tetrahydrobenzodiazepine Inhibitors of Farnesyltransferase

A Facile Synthesis of (S)-3-Tosyloxy-1,2-propanediol from (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol

Structure/activity relationships in the L-alanine taste receptor system of the channel catfish, Ictalurus punctatus

Peptide based P21 RAS farnesyl transferase inhibitors: systematic modification of the tetrapeptide CA 1A 2X motif

ChemInform Abstract: Synthesis and β‐Adrenergic Antagonist Activity of Stereoisomeric Practolol and Propranolol Derivatives

ChemInform Abstract: A Facile Synthesis of (S)‐3‐Tosyloxy‐1,2‐propanediol (V) from (S)‐2,2‐Dimethyl‐1,3‐dioxolane‐4‐methanol (I)

Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI)

Enhancing the Visibility of Women in the ACS Division of Medicinal Chemistry (ACS MEDI)

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