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Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures

Antimicrobial Agents and Chemotherapy, 2011-08, Vol.55 (8), p.3795-3802

2011

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Isolation and Structures of Axistatins 1–3 from the Republic of Palau Marine Sponge Agelas axifera Hentschel

Journal of natural products (Washington, D.C.), 2013-03, Vol.76 (3), p.420-424

2013

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Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes

ACS medicinal chemistry letters, 2011-03, Vol.2 (3), p.224-229

2011

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HPLC Biogram Analysis: A Powerful Tool Used for Hit Confirmation in Early Drug Discovery

Journal of biomolecular screening, 2015-06, Vol.20 (5), p.681-687

2015

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High-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virus

PloS one, 2012-08, Vol.7 (8), p.e42609-e42609

2012

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Comparative biotransformation of pyrazinone-containing corticotropin-releasing factor receptor-1 antagonists: minimizing the reactive metabolite formation

Drug metabolism and disposition, 2010-01, Vol.38 (1), p.5-15

2010

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Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp: I. Taxonomy, Fermentation and Biological Activities

The Journal of Antibiotics, 2003/03/25, Vol.56(3), pp.226-231

2003

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Conformation and Absolute Configuration of Nocathiacin I Determined by NMR Spectroscopy and Chiral Capillary Electrophoresis

Journal of the American Chemical Society, 2002-06, Vol.124 (25), p.7284-7285

2002

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Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp: II. Isolation, Characterization, and Structure Determination

The Journal of Antibiotics, 2003/03/25, Vol.56(3), pp.232-242

2003

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Phosphocholine conjugation: an unexpected in vivo conjugation pathway associated with hepatitis c ns5b inhibitors featuring a bicyclo[1.1.1]pentane

Drug metabolism and disposition, 2016-08, Vol.44 (8), p.1332-1340

2016

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Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement

Drug metabolism and disposition, 2016-06, Vol.44 (6), p.809-820

2016

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Metabolism of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): identification of an unusual N-acetylglucosamine conjugate in the cynomolgus monkey

Drug metabolism and disposition, 2008-12, Vol.36 (12), p.2475-2483

2008

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Labware additives identified to be selective monoamine oxidase-B inhibitors

Journal of biomolecular screening, 2014-12, Vol.19 (10), p.1409-1414

2014

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Kedarcidin, a new chromoprotein antitumor antibiotic: structure elucidation of kedarcidin chromophore

Journal of the American Chemical Society, 1992-09, Vol.114 (20), p.7946-7948

1992

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Improving the LC-MS bioanalysis of hydrophilic peptides utilizing vacuum-based sample preparation

Analytical methods, 2014-01, Vol.6 (13), p.4885-4888

2014

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Donepezil primarily attenuates scopolamine-induced deficits in psychomotor function, with moderate effects on simple conditioning and attention, and small effects on working memory and spatial mapping

Psychopharmacology, 2006-11, Vol.188 (4), p.629-640

2006

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Chemistry and structure elucidation of the kedarcidin chromophore

Journal of the American Chemical Society, 1993-09, Vol.115 (18), p.8432-8443

1993

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Antineoplastic agents. 219. Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp

Journal of medicinal chemistry, 1991-11, Vol.34 (11), p.3339-3340

1991

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Extraction, Identification, and Functional Characterization of a Bioactive Substance From Automated Compound-Handling Plastic Tips

Journal of biomolecular screening, 2009-06, Vol.14 (5), p.566-572

2009

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Best Practices in Compound Management for Preserving Compound Integrity and Accurately Providing Samples for Assays

Journal of biomolecular screening, 2009-06, Vol.14 (5), p.476-484

2009

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Cytotoxic Xanthones from Psorospermum molluscum from the Madagascar Rain Forest

Journal of natural products (Washington, D.C.), 2008-03, Vol.71 (3), p.460-463

2008

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Synthesis of Novel Nocathiacin-Class Antibiotics. Condensation of Glycolaldehyde with Primary Amides and Tandem Reductive Amination of Amadori-Rearranged 2-Oxoethyl Intermediates

Journal of organic chemistry, 2002-12, Vol.67 (25), p.8789-8793

2002

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Adverse Effects of Gabapentin and Lack of Anti-Allodynic Efficacy of Amitriptyline in the Streptozotocin Model of Painful Diabetic Neuropathy

Experimental and clinical psychopharmacology, 2006-02, Vol.14 (1), p.42-51

2006

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Ascosteroside, a New Antifungal Agent from Ascotricha amphitricha: II. Isolation and Structure Elucidation

The Journal of Antibiotics, 1996/06/25, Vol.49(6), pp.553-559

1996

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BMS-182123, a Fungal Metabolite that Inhibits the Production of TNF-α by Macrophages and Monocytes

The Journal of Antibiotics, 1996/03/25, Vol.49(3), pp.234-240

1996

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Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures

Isolation and Structures of Axistatins 1–3 from the Republic of Palau Marine Sponge Agelas axifera Hentschel

Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes

HPLC Biogram Analysis: A Powerful Tool Used for Hit Confirmation in Early Drug Discovery

High-throughput screening and rapid inhibitor triage using an infectious chimeric Hepatitis C virus

Comparative biotransformation of pyrazinone-containing corticotropin-releasing factor receptor-1 antagonists: minimizing the reactive metabolite formation

Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp: I. Taxonomy, Fermentation and Biological Activities

Conformation and Absolute Configuration of Nocathiacin I Determined by NMR Spectroscopy and Chiral Capillary Electrophoresis

Nocathiacins, New Thiazolyl Peptide Antibiotics from Nocardia sp: II. Isolation, Characterization, and Structure Determination

Phosphocholine conjugation: an unexpected in vivo conjugation pathway associated with hepatitis c ns5b inhibitors featuring a bicyclo[1.1.1]pentane

Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement

Metabolism of 5-isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): identification of an unusual N-acetylglucosamine conjugate in the cynomolgus monkey

Labware additives identified to be selective monoamine oxidase-B inhibitors

Kedarcidin, a new chromoprotein antitumor antibiotic: structure elucidation of kedarcidin chromophore

Improving the LC-MS bioanalysis of hydrophilic peptides utilizing vacuum-based sample preparation

Donepezil primarily attenuates scopolamine-induced deficits in psychomotor function, with moderate effects on simple conditioning and attention, and small effects on working memory and spatial mapping

Chemistry and structure elucidation of the kedarcidin chromophore

Antineoplastic agents. 219. Isolation and structure of the cell growth inhibitory constituents from the western Pacific marine sponge Axinella sp

Extraction, Identification, and Functional Characterization of a Bioactive Substance From Automated Compound-Handling Plastic Tips

Best Practices in Compound Management for Preserving Compound Integrity and Accurately Providing Samples for Assays

Cytotoxic Xanthones from Psorospermum molluscum from the Madagascar Rain Forest

Synthesis of Novel Nocathiacin-Class Antibiotics. Condensation of Glycolaldehyde with Primary Amides and Tandem Reductive Amination of Amadori-Rearranged 2-Oxoethyl Intermediates

Adverse Effects of Gabapentin and Lack of Anti-Allodynic Efficacy of Amitriptyline in the Streptozotocin Model of Painful Diabetic Neuropathy

Ascosteroside, a New Antifungal Agent from Ascotricha amphitricha: II. Isolation and Structure Elucidation

BMS-182123, a Fungal Metabolite that Inhibits the Production of TNF-α by Macrophages and Monocytes

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