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Emerging Mechanisms by which EMT Programs Control Stemness

Trends in Cancer, 2020-09, Vol.6 (9), p.775-780

2020

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EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling

Proceedings of the National Academy of Sciences - PNAS, 2017-12, Vol.114 (49), p.E10532-E10539

2017

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Life and death decisions by the E2F transcription factors

Current opinion in cell biology, 2007-12, Vol.19 (6), p.649-657

2007

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Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

Cancer cell, 2017-10, Vol.32 (4), p.411-426.e11

2017

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p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage

Cancer cell, 2007-02, Vol.11 (2), p.175-189

2007

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BMI1 is required for melanocyte stem cell maintenance and hair pigmentation

Pigment cell and melanoma research, 2023-09, Vol.36 (5), p.399-406

2023

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Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (33), p.11857-11862

2008

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The retinoblastoma protein induces apoptosis directly at the mitochondria

Genes & development, 2013-05, Vol.27 (9), p.1003-1015

2013

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Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

Nature communications, 2017-07, Vol.8 (1), p.15857-15857, Article 15857

2017

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Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation

Genes & development, 2015-09, Vol.29 (17), p.1875-1889

2015

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Cell size is a determinant of stem cell potential during aging

Science advances, 2021-11, Vol.7 (46), p.eabk0271-eabk0271

2021

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Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein

Cancer cell, 2009-03, Vol.15 (3), p.184-194

2009

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Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (33), p.11851-11856

2008

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Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (30), p.10408-10413

2008

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Many ribosomal protein genes are cancer genes in zebrafish

PLoS biology, 2004-05, Vol.2 (5), p.E139-0690

2004

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A vertebrate gene, ticrr, is an essential checkpoint and replication regulator

Genes & development, 2010-01, Vol.24 (2), p.183-194

2010

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Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1

Cancer cell, 2012-06, Vol.21 (6), p.848-855

2012

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DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint

Genes & development, 2006-11, Vol.20 (22), p.3117-3129

2006

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Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

Genes & development, 2004-06, Vol.18 (12), p.1413-1422

2004

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Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery

PLoS genetics, 2013-08, Vol.9 (8), p.e1003734-e1003734

2013

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Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (39), p.16940-16945

2010

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Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

Disease models & mechanisms, 2015-08, Vol.8 (8), p.941-955

2015

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An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

Science advances, 2021-10, Vol.7 (44), p.eabf6063

2021

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MITF deficiency accelerates GNAQ-driven uveal melanoma

Proceedings of the National Academy of Sciences - PNAS, 2022-05, Vol.119 (19), p.e2107006119

2022

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Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance

Cancer research (Chicago, Ill.), 2019-11, Vol.79 (22), p.5723-5733

2019

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Emerging Mechanisms by which EMT Programs Control Stemness

EMT programs promote basal mammary stem cell and tumor-initiating cell stemness by inducing primary ciliogenesis and Hedgehog signaling

Life and death decisions by the E2F transcription factors

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

p53-Deficient Cells Rely on ATM- and ATR-Mediated Checkpoint Signaling through the p38MAPK/MK2 Pathway for Survival after DNA Damage

BMI1 is required for melanocyte stem cell maintenance and hair pigmentation

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

The retinoblastoma protein induces apoptosis directly at the mitochondria

Cytoplasmic E2f4 forms organizing centres for initiation of centriole amplification during multiciliogenesis

Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation

Cell size is a determinant of stem cell potential during aging

Proapoptotic Function of the Retinoblastoma Tumor Suppressor Protein

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage

Loss of p53 synthesis in zebrafish tumors with ribosomal protein gene mutations

Many ribosomal protein genes are cancer genes in zebrafish

A vertebrate gene, ticrr, is an essential checkpoint and replication regulator

Proliferation and Tumorigenesis of a Murine Sarcoma Cell Line in the Absence of DICER1

DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint

Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery

Highly aneuploid zebrafish malignant peripheral nerve sheath tumors have genetic alterations similar to human cancers

Variations in dysfunction of sister chromatid cohesion in esco2 mutant zebrafish reflect the phenotypic diversity of Roberts syndrome

An EMT-primary cilium-GLIS2 signaling axis regulates mammogenesis and claudin-low breast tumorigenesis

MITF deficiency accelerates GNAQ-driven uveal melanoma

Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance

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