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A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels

The Journal of biological chemistry, 2020-03, Vol.295 (13), p.4341-4349

2020

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The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice

eLife, 2019-12, Vol.8

2019

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Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

Blood, 2009-07, Vol.114 (1), p.181-186

2009

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Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 Gangliosidosis

Journal of lipid research, 2023-12, Vol.64 (12), p.100463-100463, Article 100463

2023

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High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

Nature medicine, 2007-09, Vol.13 (9), p.1096-1101

2007

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IGF2BP1 overexpression causes fetal-like hemoglobin expression patterns in cultured human adult erythroblasts

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (28), p.E5664-E5672

2017

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Tough decoy targeting of predominant let-7 miRNA species in adult human hematopoietic cells

Journal of translational medicine, 2017-08, Vol.15 (1), p.169-169, Article 169

2017

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HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts

PloS one, 2016-11, Vol.11 (11), p.e0166928-e0166928

2016

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Absolute Reticulocyte Count Acts as a Surrogate for Fetal Hemoglobin in Infants and Children with Sickle Cell Anemia

PloS one, 2015-09, Vol.10 (9), p.e0136672-e0136672

2015

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Erythroid-Specific Expression of LIN28A Is Sufficient for Robust Gamma-Globin Gene and Protein Expression in Adult Erythroblasts

PloS one, 2015-12, Vol.10 (12), p.e0144977-e0144977

2015

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The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.429-440

2020

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LIN28A expression reduces sickling of cultured human erythrocytes

PloS one, 2014-09, Vol.9 (9), p.e106924-e106924

2014

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Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life

PloS one, 2013-08, Vol.8 (8), p.e70794-e70794

2013

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Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium

Journal of tissue engineering and regenerative medicine, 2016-02, Vol.10 (2), p.E84-E89

2016

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Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

Journal of translational medicine, 2009-11, Vol.7 (1), p.98-98, Article 98

2009

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Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping

Blood, 2015-07, Vol.126 (5), p.665-672

2015

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A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors

PloS one, 2013-07, Vol.8 (7), p.e68307-e68307

2013

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SARS‐CoV‐2 ORF3a expression in brain disrupts the autophagy–lysosomal pathway, impairs sphingolipid homeostasis, and drives neuropathogenesis

The FASEB journal, 2023-05, Vol.37 (5), p.e22919-n/a

2023

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LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

Blood, 2013-08, Vol.122 (6), p.1034-1041

2013

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Identification of a cross‐reacting, monoclonal anti‐human CD233 antibody for identification and sorting of rhesus macaque erythrocytes

Cytometry. Part A, 2012-02, Vol.81A (2), p.165-168

2012

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Deletion of GBA in neurons, but not microglia, causes neurodegeneration in a Gaucher mouse model

JCI insight, 2024-09

2024

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Distinct Ldb1/NLI complexes orchestrate γ-globin repression and reactivation through ETO2 in human adult erythroid cells

Blood, 2011-12, Vol.118 (23), p.6200-6208

2011

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Cloning and Characterization of a Gene Expressed during Terminal Differentiation That Encodes a Novel Inhibitor of Growth

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.1916-1921

2004

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Hembase: browser and genome portal for hematology and erythroid biology

Nucleic acids research, 2004-01, Vol.32 (Database issue), p.D572-574

2004

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Iron dose‐dependent differentiation and enucleation of human erythroblasts in serum‐free medium

Journal of tissue engineering and regenerative medicine, 2016-02, Vol.10 (2), p.E84-E89

2016

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A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels

The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice

Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells

Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 Gangliosidosis

High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin

IGF2BP1 overexpression causes fetal-like hemoglobin expression patterns in cultured human adult erythroblasts

Tough decoy targeting of predominant let-7 miRNA species in adult human hematopoietic cells

HMGA2 Moderately Increases Fetal Hemoglobin Expression in Human Adult Erythroblasts

Absolute Reticulocyte Count Acts as a Surrogate for Fetal Hemoglobin in Infants and Children with Sickle Cell Anemia

Erythroid-Specific Expression of LIN28A Is Sufficient for Robust Gamma-Globin Gene and Protein Expression in Adult Erythroblasts

The mRNA-Binding Protein IGF2BP1 Restores Fetal Hemoglobin in Cultured Erythroid Cells from Patients with β-Hemoglobin Disorders

LIN28A expression reduces sickling of cultured human erythrocytes

Increased reticulocytosis during infancy is associated with increased hospitalizations in sickle cell anemia patients during the first three years of life

Iron dose-dependent differentiation and enucleation of human erythroblasts in serum-free medium

Let-7 microRNAs are developmentally regulated in circulating human erythroid cells

Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping

A synthetic model of human beta-thalassemia erythropoiesis using CD34+ cells from healthy adult donors

SARS‐CoV‐2 ORF3a expression in brain disrupts the autophagy–lysosomal pathway, impairs sphingolipid homeostasis, and drives neuropathogenesis

LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo

Identification of a cross‐reacting, monoclonal anti‐human CD233 antibody for identification and sorting of rhesus macaque erythrocytes

Deletion of GBA in neurons, but not microglia, causes neurodegeneration in a Gaucher mouse model

Distinct Ldb1/NLI complexes orchestrate γ-globin repression and reactivation through ETO2 in human adult erythroid cells

Cloning and Characterization of a Gene Expressed during Terminal Differentiation That Encodes a Novel Inhibitor of Growth

Hembase: browser and genome portal for hematology and erythroid biology

Iron dose‐dependent differentiation and enucleation of human erythroblasts in serum‐free medium

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