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Structure of the human GlcNAc-1-phosphotransferase αβ subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation

Nature structural & molecular biology, 2022-04, Vol.29 (4), p.348-356

2022

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Disease‐causing missense mutations within the N‐terminal transmembrane domain of GlcNAc‐1‐phosphotransferase impair endoplasmic reticulum translocation or Golgi retention

Human mutation, 2020-07, Vol.41 (7), p.1321-1328

2020

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Role of spacer‐1 in the maturation and function of GlcNAc‐1‐phosphotransferase

FEBS letters, 2017-01, Vol.591 (1), p.47-55

2017

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Multiple Domains of GlcNAc-1-phosphotransferase Mediate Recognition of Lysosomal Enzymes

The Journal of biological chemistry, 2016-04, Vol.291 (15), p.8295-8307

2016

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Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting

FEBS open bio, 2021-02, Vol.11 (2), p.367-374

2021

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Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy

Molecular therapy. Methods & clinical development, 2017-06, Vol.5 (C), p.59-65

2017

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Simple, rapid, and accurate malaria diagnostic platform using microfluidic-based immunoassay of Plasmodium falciparum lactate dehydrogenase

Nano Convergence, 2020, 7(13), , pp.1-8

2020

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An Antibody-Immobilized Silica Inverse Opal Nanostructure for Label-Free Optical Biosensors

Sensors (Basel, Switzerland), 2018-01, Vol.18 (1), p.307

2018

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In vivo toxicity assessment of angiogenesis and the live distribution of nano-graphene oxide and its PEGylated derivatives using the developing zebrafish embryo

Carbon (New York), 2015-11, Vol.93, p.431-440

2015

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Human GNPTAB stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (35), p.17515-17524

2019

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Simple and rapid detection of bacteria using a nuclease-responsive DNA probe

Analyst (London), 2018-01, Vol.143 (1), p.332-338

2018

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Maternal nanoplastic ingestion induces an increase in offspring body weight through altered lipid species and microbiota

Environment international, 2024-03, Vol.185, p.108522-108522, Article 108522

2024

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Identification of the Minimal Lysosomal Enzyme Recognition Domain in Cathepsin D

The Journal of biological chemistry, 2005-09, Vol.280 (39), p.33318-33323

2005

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Fluorescent Polypropylene Nanoplastics for Studying Uptake, Biodistribution, and Excretion in Zebrafish Embryos

ACS omega, 2022-01, Vol.7 (2), p.2467-2473

2022

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Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish

International journal of molecular sciences, 2021-11, Vol.22 (21), p.11883

2021

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Poly-γ-Glutamic Acid Complexed With Alum Induces Cross-Protective Immunity of Pandemic H1N1 Vaccine

Frontiers in immunology, 2019-07, Vol.10, p.1604-1604

2019

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Functions of the α, β, and γ Subunits of UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-phosphotransferase

The Journal of biological chemistry, 2010-01, Vol.285 (5), p.3360-3370

2010

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Analysis of Mannose 6-Phosphate Uncovering Enzyme Mutations Associated with Persistent Stuttering

The Journal of biological chemistry, 2011-11, Vol.286 (46), p.39786-39793

2011

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The Relationship between Dissolution Behavior and the Toxicity of Silver Nanoparticles on Zebrafish Embryos in Different Ionic Environments

Nanomaterials (Basel, Switzerland), 2018-08, Vol.8 (9), p.652

2018

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Murine UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-phosphotransferase Lacking the γ-Subunit Retains Substantial Activity toward Acid Hydrolases

The Journal of biological chemistry, 2007-09, Vol.282 (37), p.27198-27203

2007

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Antioxidants prevent particulate matter-induced senescence of lung fibroblasts

Heliyon, 2023-03, Vol.9 (3), p.e14179, Article e14179

2023

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Human Mannose 6-Phosphate-uncovering Enzyme Is Synthesized as a Proenzyme That Is Activated by the Endoprotease Furin

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.29737-29744

2002

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Detection of Ampicillin-Resistant E. coli Using Novel Nanoprobe-Combined Fluorescence In Situ Hybridization

Nanomaterials (Basel, Switzerland), 2019-05, Vol.9 (5), p.750

2019

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Mice lacking α/β subunits of GlcNAc-1-phosphotransferase exhibit growth retardation, retinal degeneration, and secretory cell lesions

Investigative ophthalmology & visual science, 2007-11, Vol.48 (11), p.5221-5228

2007

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Selective action of the iminosugar isofagomine, a pharmacological chaperone for mutant forms of acid-β-glucosidase

Biochemical pharmacology, 2007-05, Vol.73 (9), p.1376-1383

2007

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Structure of the human GlcNAc-1-phosphotransferase αβ subunits reveals regulatory mechanism for lysosomal enzyme glycan phosphorylation

Disease‐causing missense mutations within the N‐terminal transmembrane domain of GlcNAc‐1‐phosphotransferase impair endoplasmic reticulum translocation or Golgi retention

Role of spacer‐1 in the maturation and function of GlcNAc‐1‐phosphotransferase

Multiple Domains of GlcNAc-1-phosphotransferase Mediate Recognition of Lysosomal Enzymes

Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting

Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy

Simple, rapid, and accurate malaria diagnostic platform using microfluidic-based immunoassay of Plasmodium falciparum lactate dehydrogenase

An Antibody-Immobilized Silica Inverse Opal Nanostructure for Label-Free Optical Biosensors

In vivo toxicity assessment of angiogenesis and the live distribution of nano-graphene oxide and its PEGylated derivatives using the developing zebrafish embryo

Human GNPTAB stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum

Simple and rapid detection of bacteria using a nuclease-responsive DNA probe

Maternal nanoplastic ingestion induces an increase in offspring body weight through altered lipid species and microbiota

Identification of the Minimal Lysosomal Enzyme Recognition Domain in Cathepsin D

Fluorescent Polypropylene Nanoplastics for Studying Uptake, Biodistribution, and Excretion in Zebrafish Embryos

Differential Clearance of Aβ Species from the Brain by Brain Lymphatic Endothelial Cells in Zebrafish

Poly-γ-Glutamic Acid Complexed With Alum Induces Cross-Protective Immunity of Pandemic H1N1 Vaccine

Functions of the α, β, and γ Subunits of UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-phosphotransferase

Analysis of Mannose 6-Phosphate Uncovering Enzyme Mutations Associated with Persistent Stuttering

The Relationship between Dissolution Behavior and the Toxicity of Silver Nanoparticles on Zebrafish Embryos in Different Ionic Environments

Murine UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-phosphotransferase Lacking the γ-Subunit Retains Substantial Activity toward Acid Hydrolases

Antioxidants prevent particulate matter-induced senescence of lung fibroblasts

Human Mannose 6-Phosphate-uncovering Enzyme Is Synthesized as a Proenzyme That Is Activated by the Endoprotease Furin

Detection of Ampicillin-Resistant E. coli Using Novel Nanoprobe-Combined Fluorescence In Situ Hybridization

Mice lacking α/β subunits of GlcNAc-1-phosphotransferase exhibit growth retardation, retinal degeneration, and secretory cell lesions

Selective action of the iminosugar isofagomine, a pharmacological chaperone for mutant forms of acid-β-glucosidase

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