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Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

ACS chemical biology, 2019-11, Vol.14 (11), p.2430-2440

2019

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Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas

Diabetes (New York, N.Y.), 2020-07, Vol.69 (7), p.1549-1561

2020

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The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

Progress in retinal and eye research, 2022-07, Vol.89, p.101039-101039, Article 101039

2022

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Ocular nociception and neuropathic pain initiated by blue light stress in C57BL/6J mice

Pain (Amsterdam), 2023-07, Vol.164 (7), p.1616-1626

2023

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IL-36α Enhances Host Defense against Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas

The Journal of immunology (1950), 2021-12, Vol.207 (11), p.2868-2877

2021

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Current Scope of Online Ophthalmology Education and Curriculum Impact Due to COVID-19

Journal of academic ophthalmology (2017), 2021-07, Vol.13 (2), p.e163-e169

2021

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Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis

Journal of the American Chemical Society, 2020-03, Vol.142 (9), p.4445-4455

2020

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Tetrahydropyrrolo-diazepenones as inhibitors of ERK2 kinase

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (18), p.3788-3792

2015

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Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of β-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression

Antimicrobial agents and chemotherapy, 2019-02, Vol.63 (2)

2019

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Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline

Journal of medicinal chemistry, 2018-10, Vol.61 (20), p.9360-9370

2018

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Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms

Antimicrobial agents and chemotherapy, 2019-12, Vol.64 (1)

2019

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Altering the Allowed/Forbidden Gap in Cyclobutene Electrocyclic Reactions: Experimental and Theoretical Evaluations of the Effect of Planarity Constraints

Journal of the American Chemical Society, 2003-05, Vol.125 (19), p.5839-5848

2003

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A Standard Set of Pericyclic Reactions of Hydrocarbons for the Benchmarking of Computational Methods: The Performance of ab Initio, Density Functional, CASSCF, CASPT2, and CBS-QB3 Methods for the Prediction of Activation Barriers, Reaction Energetics, and Transition State Geometries

The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory, 2003-12, Vol.107 (51), p.11445-11459

2003

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Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase

Bioorganic & medicinal chemistry letters, 2015-09, Vol.25 (17), p.3626-3629

2015

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Polyacene and Cyclacene Geometries and Electronic Structures: Bond Equalization, Vanishing Band Gaps, and Triplet Ground States Contrast with Polyacetylene

Journal of organic chemistry, 2001-08, Vol.66 (16), p.5517-5521

2001

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Promiscuity and the Conformational Rearrangement of Drug-Like Molecules: Insight from the Protein Data Bank

ChemMedChem, 2015-02, Vol.10 (2), p.238-244

2015

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Sensory nerve regeneration after epithelium wounding in normal and diabetic corneas

Expert review of ophthalmology, 2015-07, Vol.10 (4), p.383-392

2015

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Origins of Inward Torquoselectivity by Silyl Groups and Other σ-Acceptors in Electrocyclic Reactions of Cyclobutenes

Journal of the American Chemical Society, 2003-04, Vol.125 (17), p.5072-5079

2003

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Acute macular infarctions in pediatric patients with hemoglobin SS disease

American journal of ophthalmology case reports, 2023-12, Vol.32, p.101913, Article 101913

2023

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New Insights into the Intrinsic and Extrinsic Factors That Shape the Human Skin Microbiome

mBio, 2019-07, Vol.10 (4)

2019

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Ab Interno Ahmed Glaucoma Valve Plugs In An Eye With Persistent Hypotony

Journal of glaucoma, 2024-05, Vol.33 (5), p.e21

2024

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The Origin of endo Stereoselectivity in the Hetero-Diels-Alder Reactions of Aldehydes with ortho-Xylylenes: CH-π, π-π, and Steric Effects on Stereoselectivity

Chemistry : a European journal, 2002-08, Vol.8 (15), p.3423-3430

2002

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Energetic Preferences for α,β versus β,γ Unsaturation

Journal of organic chemistry, 2004-08, Vol.69 (16), p.5448-5453

2004

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Surgically Induced Scleritis Associated With Suture Hypersensitivity Following Strabismus Surgery

Journal of pediatric ophthalmology and strabismus, 2024-01, Vol.61 (1), p.e4

2024

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1 – 25 von 13.049

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Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications

Role of VIP and Sonic Hedgehog Signaling Pathways in Mediating Epithelial Wound Healing, Sensory Nerve Regeneration, and Their Defects in Diabetic Corneas

SGX523 is an exquisitely selective, ATP-competitive inhibitor of the MET receptor tyrosine kinase with antitumor activity in vivo

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

Ocular nociception and neuropathic pain initiated by blue light stress in C57BL/6J mice

IL-36α Enhances Host Defense against Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas

Current Scope of Online Ophthalmology Education and Curriculum Impact Due to COVID-19

Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis

Tetrahydropyrrolo-diazepenones as inhibitors of ERK2 kinase

Target (MexB)- and Efflux-Based Mechanisms Decreasing the Effectiveness of the Efflux Pump Inhibitor D13-9001 in Pseudomonas aeruginosa PAO1: Uncovering a New Role for MexMN-OprM in Efflux of β-Lactams and a Novel Regulatory Circuit (MmnRS) Controlling MexMN Expression

Application of Virtual Screening to the Identification of New LpxC Inhibitor Chemotypes, Oxazolidinone and Isoxazoline

Mutations Reducing In Vitro Susceptibility to Novel LpxC Inhibitors in Pseudomonas aeruginosa and Interplay of Efflux and Nonefflux Mechanisms

Altering the Allowed/Forbidden Gap in Cyclobutene Electrocyclic Reactions: Experimental and Theoretical Evaluations of the Effect of Planarity Constraints

A Standard Set of Pericyclic Reactions of Hydrocarbons for the Benchmarking of Computational Methods: The Performance of ab Initio, Density Functional, CASSCF, CASPT2, and CBS-QB3 Methods for the Prediction of Activation Barriers, Reaction Energetics, and Transition State Geometries

Ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase

Polyacene and Cyclacene Geometries and Electronic Structures: Bond Equalization, Vanishing Band Gaps, and Triplet Ground States Contrast with Polyacetylene

Promiscuity and the Conformational Rearrangement of Drug-Like Molecules: Insight from the Protein Data Bank

Sensory nerve regeneration after epithelium wounding in normal and diabetic corneas

Origins of Inward Torquoselectivity by Silyl Groups and Other σ-Acceptors in Electrocyclic Reactions of Cyclobutenes

Acute macular infarctions in pediatric patients with hemoglobin SS disease

New Insights into the Intrinsic and Extrinsic Factors That Shape the Human Skin Microbiome

Ab Interno Ahmed Glaucoma Valve Plugs In An Eye With Persistent Hypotony

The Origin of endo Stereoselectivity in the Hetero-Diels-Alder Reactions of Aldehydes with ortho-Xylylenes: CH-π, π-π, and Steric Effects on Stereoselectivity

Energetic Preferences for α,β versus β,γ Unsaturation

Surgically Induced Scleritis Associated With Suture Hypersensitivity Following Strabismus Surgery

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