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Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast

Nucleic acids research, 2015-04, Vol.43 (8), p.e55

2015

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A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function

Nucleic acids research, 2014-12, Vol.42 (21)

2014

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Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells

Oncotarget, 2016-03, Vol.7 (12), p.14841-14856

2016

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Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System

ACS synthetic biology, 2018-01, Vol.7 (1), p.63-74

2018

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Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (5), p.1903-1908

2014

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A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

BMC cancer, 2013-05, Vol.13 (1), p.252-252, Article 252

2013

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Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4), p.902-911

2016

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Moving toward a higher efficiency of microcell-mediated chromosome transfer

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16043-16043, Article 16043

2016

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Protecting a transgene expression from the HAC-based vector by different chromatin insulators

Cellular and molecular life sciences : CMLS, 2013-10, Vol.70 (19), p.3723-3737

2013

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Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families

Genes chromosomes & cancer, 2012-10, Vol.51 (10), p.933-948

2012

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Serine recombinases as tools for genome engineering

Methods (San Diego, Calif.), 2011-04, Vol.53 (4), p.372-379

2011

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Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function

Nucleic acids research, 2013-05, Vol.41 (10), p.e107

2013

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Assembly of Multiple Full‐Size Genes or Genomic DNA Fragments on Human Artificial Chromosomes Using the Iterative Integration System

Current protocols, 2021-12, Vol.1 (12), p.e316-n/a

2021

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Rapid generation of long tandem DNA repeat arrays by homologous recombination in yeast to study their function in mammalian genomes

Biological procedures online, 2011-10, Vol.13 (1), p.8-8, Article 8

2011

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From selective full-length genes isolation by TAR cloning in yeast to their expression from HAC vectors in human cells

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1227, p.3

2015

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Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette

Nucleic acids research, 2015-05, Vol.43 (9), p.e57

2015

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Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient

Oncotarget, 2018-03, Vol.9 (20), p.15275-15291

2018

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Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (5), p.1907-1907

2014

Volltextzugriff (PDF)

Effects of Anticancer Drug on Chromosome Instability (CIN) and New Clinical Implications for Tumor-Suppressing Therapies

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4), p.902-911

2016

Volltextzugriff (PDF)

Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage phiBT1

Nucleic acids research, 2008-01, Vol.36 (1), p.e9

2008

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Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19

The New England journal of medicine, 2020-11, Vol.383 (21), p.2030-2040

2020

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Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer

The New England journal of medicine, 2015-07, Vol.373 (3), p.209-219

2015

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SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Nature communications, 2022-05, Vol.13 (1), p.2774-2774, Article 2774

2022

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Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function

Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells

Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System

Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies

Moving toward a higher efficiency of microcell-mediated chromosome transfer

Protecting a transgene expression from the HAC-based vector by different chromatin insulators

Exclusion of the 750-kb genetically unstable region at Xq27 as a candidate locus for prostate malignancy in HPCX1-linked families

Serine recombinases as tools for genome engineering

Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function

Assembly of Multiple Full‐Size Genes or Genomic DNA Fragments on Human Artificial Chromosomes Using the Iterative Integration System

Rapid generation of long tandem DNA repeat arrays by homologous recombination in yeast to study their function in mammalian genomes

From selective full-length genes isolation by TAR cloning in yeast to their expression from HAC vectors in human cells

Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette

Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient

Kinetochore assembly and heterochromatin formation occur autonomously in Schizosaccharomyces pombe

Effects of Anticancer Drug on Chromosome Instability (CIN) and New Clinical Implications for Tumor-Suppressing Therapies

Site-specific recombination in Schizosaccharomyces pombe and systematic assembly of a 400kb transgene array in mammalian cells using the integrase of Streptomyces phage phiBT1

Effect of Hydroxychloroquine in Hospitalized Patients with Covid-19

Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer

Obesity, clinical, and genetic predictors for glycemic progression in Chinese patients with type 2 diabetes: A cohort study using the Hong Kong Diabetes Register and Hong Kong Diabetes Biobank

Design, Synthesis, and Characterization of I‑BET567, a Pan-Bromodomain and Extra Terminal (BET) Bromodomain Oral Candidate

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

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