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GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH

Biochimica et biophysica acta. General subjects, 2021-03, Vol.1865 (3), p.129834-129834, Article 129834

2021

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New mechanisms of metformin action: Focusing on mitochondria and the gut

Journal of diabetes investigation, 2015-11, Vol.6 (6), p.600-609

2015

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Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance

Archives of Pharmacal Research, 2016, 39(11), , pp.1503-1518

2016

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SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

Nature communications, 2020-05, Vol.11 (1), p.2127-11, Article 2127

2020

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Gut Microbiota and Metabolic Disorders

Diabetes and Metabolism Journal, 2015, 39(3), 149, pp.198-203

2015

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A GLP‐1/GLP‐2 receptor dual agonist to treat NASH: Targeting the gut‐liver axis and microbiome

Hepatology (Baltimore, Md.), 2022-06, Vol.75 (6), p.1523-1538

2022

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Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

Molecular cell, 2013-09, Vol.51 (5), p.618-631

2013

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Role of β‐cell autophagy in β‐cell physiology and the development of diabetes

Journal of diabetes investigation, 2024-06, Vol.15 (6), p.656-668

2024

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Autophagy induction can regulate skin pigmentation by causing melanosome degradation in keratinocytes and melanocytes

Pigment cell and melanoma research, 2020-05, Vol.33 (3), p.403-415

2020

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Effect of mitochondrial stress on systemic metabolism

Annals of the New York Academy of Sciences, 2015-09, Vol.1350 (1), p.61-65

Lee, Myung-Shik

2015

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Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches

Frontiers in endocrinology (Lausanne), 2018-08, Vol.9, p.485-485

2018

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β-cell autophagy: Mechanism and role in β-cell dysfunction

Molecular metabolism (Germany), 2019-09, Vol.27 (Suppl), p.S92-S103

2019

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Role of mitochondrial function in cell death and body metabolism

Frontiers in bioscience, 2016-06, Vol.21 (6), p.1233-1244, Article 4453

Lee, Myung-Shik

2016

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FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs

Journal of endocrinology, 2015-07, Vol.226 (1), p.R1-R16

2015

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A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

Nature communications, 2018-04, Vol.9 (1), p.1438-14, Article 1438

2018

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Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

The Journal of cell biology, 2011-04, Vol.193 (2), p.275-284

2011

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Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition

Autophagy, 2017-10, Vol.13 (10), p.1767-1781

2017

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Autophagy--a key player in cellular and body metabolism

Nature reviews. Endocrinology, 2014-06, Vol.10 (6), p.322-337

2014

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Acute exercise induces FGF21 expression in mice and in healthy humans

PloS one, 2013-05, Vol.8 (5), p.e63517-e63517

2013

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Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

Nature medicine, 2013-01, Vol.19 (1), p.83-92

2013

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Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice

Scientific reports, 2018-05, Vol.8 (1), p.6789-14, Article 6789

2018

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Mitochondrial event as an ultimate step in ferroptosis

Cell death discovery, 2022-10, Vol.8 (1), p.414-414, Article 414

2022

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Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes

Nature communications, 2014-09, Vol.5 (1), p.4934-4934, Article 4934

2014

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Role of Autophagy in the Pathogenesis of Diabetes and Therapeutic Potential of Autophagy Modulators in the Treatment of Diabetes and Metabolic Syndrome

Journal of Korean Medical Science, 2022, 37(37), , pp.1-17

2022

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GDF15 as a central mediator for integrated stress response and a promising therapeutic molecule for metabolic disorders and NASH

New mechanisms of metformin action: Focusing on mitochondria and the gut

Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance

SGLT2 inhibition modulates NLRP3 inflammasome activity via ketones and insulin in diabetes with cardiovascular disease

Gut Microbiota and Metabolic Disorders

A GLP‐1/GLP‐2 receptor dual agonist to treat NASH: Targeting the gut‐liver axis and microbiome

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

Role of β‐cell autophagy in β‐cell physiology and the development of diabetes

Autophagy induction can regulate skin pigmentation by causing melanosome degradation in keratinocytes and melanocytes

Effect of mitochondrial stress on systemic metabolism

Pathogenesis of Nonalcoholic Steatohepatitis and Hormone-Based Therapeutic Approaches

β-cell autophagy: Mechanism and role in β-cell dysfunction

Role of mitochondrial function in cell death and body metabolism

FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

Ezetimibe ameliorates steatohepatitis via AMP activated protein kinase-TFEB-mediated activation of autophagy and NLRP3 inflammasome inhibition

Autophagy--a key player in cellular and body metabolism

Acute exercise induces FGF21 expression in mice and in healthy humans

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

Growth differentiation factor 15 ameliorates nonalcoholic steatohepatitis and related metabolic disorders in mice

Mitochondrial event as an ultimate step in ferroptosis

Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes

Role of Autophagy in the Pathogenesis of Diabetes and Therapeutic Potential of Autophagy Modulators in the Treatment of Diabetes and Metabolic Syndrome

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