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Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

Cell stem cell, 2014-02, Vol.14 (2), p.237-252

2014

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A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy-Affected Skeletal Muscles

Stem cells translational medicine, 2016-09, Vol.5 (9), p.1145-1161

2016

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A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition

Scientific reports, 2021-02, Vol.11 (1), p.4538-14, Article 4538

2021

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The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer

PloS one, 2015-08, Vol.10 (8), p.e0134496-e0134496

2015

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Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover

PLoS biology, 2007-03, Vol.5 (3), p.e67-e67

2007

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Generating specificity and diversity in the transcriptional response to hypoxia

Nature reviews. Genetics, 2009-12, Vol.10 (12), p.821-832

2009

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A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

Cell reports (Cambridge), 2018-02, Vol.22 (8), p.2190-2205

2018

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Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells

Scientific reports, 2017-06, Vol.7 (1), p.4108-17, Article 4108

2017

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Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types

Epigenetics, 2023-12, Vol.18 (1), p.2222245-2222245

2023

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Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition

Blood, 2014-05, Vol.123 (21), p.3316-3326

2014

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Validation and refinement of a RUNX1 mutation-associated gene expression signature in blast crisis chronic myeloid leukemia

Leukemia, 2022-03, Vol.36 (3), p.892-896

2022

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SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia

Leukemia, 2020-07, Vol.34 (7), p.1787-1798

2020

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HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promoters

Experimental cell research, 2018-05, Vol.366 (2), p.181-191

2018

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Arkadia Induces Degradation of SnoN and c-Ski to Enhance Transforming Growth Factor-β Signaling

The Journal of biological chemistry, 2007-07, Vol.282 (28), p.20492-20501

2007

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Heparan Sulfation–Dependent Fibroblast Growth Factor Signaling Maintains Embryonic Stem Cells Primed for Differentiation in a Heterogeneous State

Stem cells (Dayton, Ohio), 2010-02, Vol.28 (2), p.191-200

2010

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Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions

PLoS genetics, 2011-06, Vol.7 (6), p.e1002130-e1002130

2011

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The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target

PloS one, 2018-10, Vol.13 (10), p.e0205254-e0205254

2018

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Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells

Oncotarget, 2014-07, Vol.5 (13), p.4881-4894

2014

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Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway

PloS one, 2017-11, Vol.12 (11), p.e0188051-e0188051

2017

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The Hypoxia-Inducible Epigenetic Regulators Jmjd1a and G9a Provide a Mechanistic Link between Angiogenesis and Tumor Growth

Molecular and cellular biology, 2014-10, Vol.34 (19), p.3702-3720

2014

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Down-regulation of Myc Is Essential for Terminal Erythroid Maturation

The Journal of biological chemistry, 2010-12, Vol.285 (51), p.40252-40265

2010

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Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells

Oncotarget, 2018-04, Vol.9 (27), p.19123-19135

2018

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Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

Scientific reports, 2017-08, Vol.7 (1), p.7190-11, Article 7190

2017

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Author Correction: Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

Scientific reports, 2018-07, Vol.8 (1), p.11239-1, Article 11239

2018

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Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations

A Human Pluripotent Stem Cell Model of Facioscapulohumeral Muscular Dystrophy-Affected Skeletal Muscles

A KDM6 inhibitor potently induces ATF4 and its target gene expression through HRI activation and by UTX inhibition

The A Allele at rs13419896 of EPAS1 Is Associated with Enhanced Expression and Poor Prognosis for Non-Small Cell Lung Cancer

Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover

Generating specificity and diversity in the transcriptional response to hypoxia

A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells

Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells

Catalytic domain-dependent and -independent transcriptional activities of the tumour suppressor histone H3K27 demethylase UTX/KDM6A in specific cancer types

An integrative model of pathway convergence in genetically heterogeneous blast crisis chronic myeloid leukemia

Physiologic hypoxia promotes maintenance of CML stem cells despite effective BCR-ABL1 inhibition

Validation and refinement of a RUNX1 mutation-associated gene expression signature in blast crisis chronic myeloid leukemia

SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia

HIF-dependent and reversible nucleosome disassembly in hypoxia-inducible gene promoters

Arkadia Induces Degradation of SnoN and c-Ski to Enhance Transforming Growth Factor-β Signaling

Heparan Sulfation–Dependent Fibroblast Growth Factor Signaling Maintains Embryonic Stem Cells Primed for Differentiation in a Heterogeneous State

Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions

The arginase inhibitor Nω-hydroxy-nor-arginine (nor-NOHA) induces apoptosis in leukemic cells specifically under hypoxic conditions but CRISPR/Cas9 excludes arginase 2 (ARG2) as the functional target

Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells

Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway

The Hypoxia-Inducible Epigenetic Regulators Jmjd1a and G9a Provide a Mechanistic Link between Angiogenesis and Tumor Growth

Down-regulation of Myc Is Essential for Terminal Erythroid Maturation

Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells

Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

Author Correction: Interaction between von Hippel-Lindau Protein and Fatty Acid Synthase Modulates Hypoxia Target Gene Expression

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