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In Vivo Pharmacokinetics and Pharmacodynamics of Positional Isomers of Mono-PEGylated Recombinant Human Granulocyte Colony Stimulating Factor in Rats

Biological and Pharmaceutical Bulletin, 2013/07/01, Vol.36(7), pp.1146-1151

2013

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Low Molecular Weight (1 kDa) Polyethylene Glycol Conjugation Markedly Enhances the Hypoglycemic Effects of Intranasally Administered Exendin-4 in Type 2 Diabetic db/db Mice

Biological and Pharmaceutical Bulletin, 2012/07/01, Vol.35(7), pp.1076-1083

2012

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Preparation and Structural, Biochemical, and Pharmaceutical Characterizations of Bile Acid-Modified Long-Acting Exendin-4 Derivatives

Journal of medicinal chemistry, 2009-11, Vol.52 (21), p.6889-6896

2009

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Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity

International journal of pharmaceutics, 2011-01, Vol.403 (1-2), p.285-291

2011

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Doxorubicin-loaded highly porous large PLGA microparticles as a sustained- release inhalation system for the treatment of metastatic lung cancer

Biomaterials, 2012-08, Vol.33 (22), p.5574-5583

2012

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Determination of metoclopramide in human plasma using hydrophilic interaction chromatography with tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-06, Vol.877 (18), p.1716-1720

2009

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Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease

Acta neuropathologica communications, 2021-04, Vol.9 (1), p.78-15, Article 78

2021

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Controlled release of insulin from pH/temperature-sensitive injectable pentablock copolymer hydrogel

Journal of controlled release, 2009-07, Vol.137 (1), p.20-24

2009

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Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects

Journal of controlled release, 2021-08, Vol.336, p.181-191

2021

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Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

Hepatology (Baltimore, Md.), 2016-07, Vol.64 (1), p.209-223

2016

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Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

Nature communications, 2019-03, Vol.10 (1), p.1128-1128, Article 1128

2019

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PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

Journal of controlled release, 2017-12, Vol.267, p.163-171

2017

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The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics

Journal of controlled release, 2010-05, Vol.144 (1), p.10-16

2010

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Self-assembled glycol chitosan nanogels containing palmityl-acylated exendin-4 peptide as a long-acting anti-diabetic inhalation system

Journal of controlled release, 2012-08, Vol.161 (3), p.728-734

2012

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Liquid chromatography–mass spectrometric method for the sensitive determination of niflumic acid in human plasma and its application to pharmacokinetic study of talniflumate tablet

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-12, Vol.876 (2), p.159-162

2008

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Multiplex Imaging of an Intracellular Proteolytic Cascade by using a Broad-Spectrum Nanoquencher

Angewandte Chemie International Edition, 2012-02, Vol.51 (7), p.1625-1630

International ed. in English, 2012

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Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes

International journal of nanomedicine, 2013-01, Vol.8 (1), p.2975-2983

2013

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Differences in electrophoretic behavior between linear and branched PEG-conjugated proteins

Electrophoresis, 2015-03, Vol.36 (6), p.918-923

2015

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PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting

Journal of controlled release, 2012-09, Vol.162 (2), p.422-428

2012

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PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity

Journal of controlled release, 2011-02, Vol.150 (1), p.63-69

2011

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Emerging PEGylated drugs

Expert opinion on emerging drugs, 2009-06, Vol.14 (2), p.363-380

2009

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Development and validation of a reversed-phase fluorescence HPLC method for determination of bucillamine in human plasma using pre-column derivatization with monobromobimane

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2009-07, Vol.877 (22), p.2130-2134

2009

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Albumin-Coated Porous Hollow Poly(Lactic-co-Glycolic Acid) Microparticles Bound with Palmityl-Acylated Exendin-4 as a Long-Acting Inhalation Delivery System for the Treatment of Diabetes

Pharmaceutical research, 2011-08, Vol.28 (8), p.2008-2019

2011

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Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs

Journal of controlled release, 2010-03, Vol.142 (2), p.206-213

2010

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In Vivo Pharmacokinetics and Pharmacodynamics of Positional Isomers of Mono-PEGylated Recombinant Human Granulocyte Colony Stimulating Factor in Rats

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

Low Molecular Weight (1 kDa) Polyethylene Glycol Conjugation Markedly Enhances the Hypoglycemic Effects of Intranasally Administered Exendin-4 in Type 2 Diabetic db/db Mice

Preparation and Structural, Biochemical, and Pharmaceutical Characterizations of Bile Acid-Modified Long-Acting Exendin-4 Derivatives

Preparation and characterization of water-soluble albumin-bound curcumin nanoparticles with improved antitumor activity

Doxorubicin-loaded highly porous large PLGA microparticles as a sustained- release inhalation system for the treatment of metastatic lung cancer

Determination of metoclopramide in human plasma using hydrophilic interaction chromatography with tandem mass spectrometry

Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer's disease

Controlled release of insulin from pH/temperature-sensitive injectable pentablock copolymer hydrogel

Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects

Systemic PEGylated TRAIL treatment ameliorates liver cirrhosis in rats by eliminating activated hepatic stellate cells

Targeting of dermal myofibroblasts through death receptor 5 arrests fibrosis in mouse models of scleroderma

PEGylated TRAIL ameliorates experimental inflammatory arthritis by regulation of Th17 cells and regulatory T cells

The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics

Self-assembled glycol chitosan nanogels containing palmityl-acylated exendin-4 peptide as a long-acting anti-diabetic inhalation system

Liquid chromatography–mass spectrometric method for the sensitive determination of niflumic acid in human plasma and its application to pharmacokinetic study of talniflumate tablet

Multiplex Imaging of an Intracellular Proteolytic Cascade by using a Broad-Spectrum Nanoquencher

Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes

Differences in electrophoretic behavior between linear and branched PEG-conjugated proteins

PEG-transferrin conjugated TRAIL (TNF-related apoptosis-inducing ligand) for therapeutic tumor targeting

PEGylated TNF-related apoptosis-inducing ligand (TRAIL)-loaded sustained release PLGA microspheres for enhanced stability and antitumor activity

Emerging PEGylated drugs

Development and validation of a reversed-phase fluorescence HPLC method for determination of bucillamine in human plasma using pre-column derivatization with monobromobimane

Albumin-Coated Porous Hollow Poly(Lactic-co-Glycolic Acid) Microparticles Bound with Palmityl-Acylated Exendin-4 as a Long-Acting Inhalation Delivery System for the Treatment of Diabetes

Biochemical, pharmaceutical and therapeutic properties of long-acting lithocholic acid derivatized exendin-4 analogs

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