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Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies

European journal of pharmacology, 2009-12, Vol.625 (1), p.220-233

2009

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The Potential of Combining Tubulin-Targeting Anticancer Therapeutics and Immune Therapy

International journal of molecular sciences, 2019-01, Vol.20 (3), p.586

2019

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The Akt isoforms are present at distinct subcellular locations

American Journal of Physiology: Cell Physiology, 2010-03, Vol.298 (3), p.C580-C591

2010

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Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: A hybrid pharmacophore approach

Bioorganic & medicinal chemistry, 2010-02, Vol.18 (4), p.1563-1572

2010

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Design and synthesis of 4-piperazinyl quinoline derived urea/thioureas for anti-breast cancer activity by a hybrid pharmacophore approach

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.620-630

2019

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Raja 42, a novel gamma lactam compound, is effective against Clostridioides difficile

PloS one, 2021-09, Vol.16 (9), p.e0257143-e0257143

2021

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Lead optimization of novel quinolone chalcone compounds by a structure-activity relationship (SAR) study to increase efficacy and metabolic stability

Scientific reports, 2021-11, Vol.11 (1), p.21576-16, Article 21576

2021

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Ablation of Akt2 induces autophagy through cell cycle arrest, the downregulation of p70S6K, and the deregulation of mitochondria in MDA-MB231 cells

PloS one, 2011-01, Vol.6 (1), p.e14614-e14614

2011

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Anti-breast cancer activity of heteroaryl chalcone derivatives

Biomedicine & pharmacotherapy, 2012-04, Vol.66 (3), p.213-220

2012

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Cytotoxic and Anti-Plasmodial Activities of Stephania dielsiana Y.C. Wu Extracts and the Isolated Compounds

Molecules (Basel, Switzerland), 2020-08, Vol.25 (16), p.3755

2020

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Origin of DNA replication at the human lamin B2 locus: OBR or ABR?

Cell cycle (Georgetown, Tex.), 2012-11, Vol.11 (22), p.4281-4283

2012

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Synthesis and biological evaluation of 2-(phenyl)-3H-benzo[d]imidazole-5-carboxylic acids and its methyl esters as potent anti-breast cancer agents

Arabian journal of chemistry, 2017-05, Vol.10 (S2), p.S1788-S1794

2017

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The VR23 anticancer proteasome inhibitor also exhibits anti-inflammatory activity through the downregulation of the IL-6-JAK-STAT pathway

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.237-237.17

2020

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Same partners, different dance: Involvement of DNA replication proteins in centrosome regulation

Cell cycle (Georgetown, Tex.), 2010-11, Vol.9 (22), p.4487-4491

2010

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Chloroquine-based hybrid molecules as promising novel chemotherapeutic agents

European journal of pharmacology, 2015-09, Vol.762, p.472-486

2015

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Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents

Bioorganic & medicinal chemistry, 2015-12, Vol.23 (24), p.7629-7640

2015

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Asian medicine: Many unique types

Nature (London), 2012-02, Vol.482 (7383), p.35-35

Lee, Hoyun

2012

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Proliferating Cell Nuclear Antigen (PCNA) May Function as a Double Homotrimer Complex in the Mammalian Cell

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.13888-13894

2005

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Lys-110 is essential for targeting PCNA to replication and repair foci, and the K110A mutant activates apoptosis

Biology of the cell, 2008-12, Vol.100 (12), p.675-686

2008

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The VR23 Antitumor Compound Also Shows Strong Anti-Inflammatory Effects in a Human Rheumatoid Arthritis Cell Model and Acute Lung Inflammation in Mice

The Journal of immunology (1950), 2020-02, Vol.204 (4), p.788-795

2020

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Two birds with one stone

Cell cycle (Georgetown, Tex.), 2015-03, Vol.14 (6), p.801-801

2015

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Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines

Letters in drug design & discovery, 2011-05, Vol.8 (4), p.308-311

2011

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Examination of novel 4-aminoquinoline derivatives designed and synthesized by a hybrid pharmacophore approach to enhance their anticancer activities

Scientific reports, 2019-04, Vol.9 (1), p.6315, Article 6315

2019

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Identification and Characterization of Human Cdc7 Nuclear Retention and Export Sequences in the Context of Chromatin Binding

The Journal of biological chemistry, 2007-10, Vol.282 (41), p.30029-30038

2007

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Design, synthesis and characterization of novel quinacrine analogs that preferentially kill cancer over non-cancer cells through the down-regulation of Bcl-2 and up-regulation of Bax and Bad

European journal of medicinal chemistry, 2017-09, Vol.137, p.156-166

2017

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Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies

The Potential of Combining Tubulin-Targeting Anticancer Therapeutics and Immune Therapy

The Akt isoforms are present at distinct subcellular locations

Design and synthesis of anti-breast cancer agents from 4-piperazinylquinoline: A hybrid pharmacophore approach

Design and synthesis of 4-piperazinyl quinoline derived urea/thioureas for anti-breast cancer activity by a hybrid pharmacophore approach

Raja 42, a novel gamma lactam compound, is effective against Clostridioides difficile

Lead optimization of novel quinolone chalcone compounds by a structure-activity relationship (SAR) study to increase efficacy and metabolic stability

Ablation of Akt2 induces autophagy through cell cycle arrest, the downregulation of p70S6K, and the deregulation of mitochondria in MDA-MB231 cells

Anti-breast cancer activity of heteroaryl chalcone derivatives

Cytotoxic and Anti-Plasmodial Activities of Stephania dielsiana Y.C. Wu Extracts and the Isolated Compounds

Origin of DNA replication at the human lamin B2 locus: OBR or ABR?

Synthesis and biological evaluation of 2-(phenyl)-3H-benzo[d]imidazole-5-carboxylic acids and its methyl esters as potent anti-breast cancer agents

The VR23 anticancer proteasome inhibitor also exhibits anti-inflammatory activity through the downregulation of the IL-6-JAK-STAT pathway

Same partners, different dance: Involvement of DNA replication proteins in centrosome regulation

Chloroquine-based hybrid molecules as promising novel chemotherapeutic agents

Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents

Asian medicine: Many unique types

Proliferating Cell Nuclear Antigen (PCNA) May Function as a Double Homotrimer Complex in the Mammalian Cell

Lys-110 is essential for targeting PCNA to replication and repair foci, and the K110A mutant activates apoptosis

The VR23 Antitumor Compound Also Shows Strong Anti-Inflammatory Effects in a Human Rheumatoid Arthritis Cell Model and Acute Lung Inflammation in Mice

Two birds with one stone

Synthesis of Some Coumarinyl Chalcones and their Antiproliferative Activity Against Breast Cancer Cell Lines

Examination of novel 4-aminoquinoline derivatives designed and synthesized by a hybrid pharmacophore approach to enhance their anticancer activities

Identification and Characterization of Human Cdc7 Nuclear Retention and Export Sequences in the Context of Chromatin Binding

Design, synthesis and characterization of novel quinacrine analogs that preferentially kill cancer over non-cancer cells through the down-regulation of Bcl-2 and up-regulation of Bax and Bad

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