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Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies

Scientific reports, 2018-03, Vol.8 (1), p.5361-11, Article 5361

2018

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Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions

Biotechnology advances, 2017-01, Vol.35 (1), p.64-76

2017

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Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Nature communications, 2020-01, Vol.11 (1), p.68-10, Article 68

2020

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Accelerated homology-directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment

Biotechnology and bioengineering, 2016-11, Vol.113 (11), p.2518-2523

2016

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Multiplex secretome engineering enhances recombinant protein production and purity

Nature communications, 2020-04, Vol.11 (1), p.1908-1908, Article 1908

2020

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Cell Culture Engineering: Recombinant Protein Production

1st edition, 2020

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Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7

Scientific reports, 2021-02, Vol.11 (1), p.3378-3378, Article 3378

2021

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Understanding of decreased sialylation of Fc‐fusion protein in hyperosmotic recombinant Chinese hamster ovary cell culture: N‐glycosylation gene expression and N‐linked glycan antennary profile

Biotechnology and bioengineering, 2017-08, Vol.114 (8), p.1721-1732

2017

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Amplification of EBNA-1 through a single-plasmid vector-based gene amplification system in HEK293 cells as an efficient transient gene expression system

Applied microbiology and biotechnology, 2021, Vol.105 (1), p.67-76

2021

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Effect of lithium chloride on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture

Applied microbiology and biotechnology, 2014-11, Vol.98 (22), p.9239-9248

2014

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The molecular weight and concentration of dextran sulfate affect cell growth and antibody production in CHO cell cultures

Biotechnology progress, 2016-09, Vol.32 (5), p.1113-1122

2016

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Limitations to the development of recombinant human embryonic kidney 293E cells using glutamine synthetase-mediated gene amplification: Methionine sulfoximine resistance

Journal of biotechnology, 2016-08, Vol.231, p.136-140

2016

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CHO cells in biotechnology for production of recombinant proteins: current state and further potential

Applied microbiology and biotechnology, 2012-02, Vol.93 (3), p.917-930

2012

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Investigation of relationship between EBNA-1 expression level and specific foreign protein productivity in transient gene expression of HEK293 cells

Process biochemistry (1991), 2017-04, Vol.55, p.182-186

2017

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Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture

Applied microbiology and biotechnology, 2014-04, Vol.98 (8), p.3509-3515

2014

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Mitigating Clonal Variation in Recombinant Mammalian Cell Lines

Trends in biotechnology (Regular ed.), 2019-09, Vol.37 (9), p.931-942

2019

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Effect of culture pH on erythropoietin production by Chinese hamster ovary cells grown in suspension at 32.5 and 37.0°C

Biotechnology and bioengineering, 2005-02, Vol.89 (3), p.345-356

2005

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Electrospun chitosan/poly(vinyl alcohol) reinforced with CaCO3 nanoparticles with enhanced mechanical properties and biocompatibility for cartilage tissue engineering

Composites science and technology, 2015-01, Vol.106, p.76-84

2015

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Untangling the mechanism of 3‐methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3‐methyladenine

Biotechnology and bioengineering, 2018-09, Vol.115 (9), p.2243-2254

2018

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Effect of glutamine substitution by TCA cycle intermediates on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture

Journal of biotechnology, 2014-06, Vol.180, p.23-29

2014

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Anti-Apoptosis Engineering for Improved Protein Production from CHO Cells

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1603, p.71

2017

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Analysis of Golgi pH in Chinese hamster ovary cells using ratiometric pH‐sensitive fluorescent proteins

Biotechnology and bioengineering, 2019-05, Vol.116 (5), p.1006-1016

2019

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Monitoring of autophagy in Chinese hamster ovary cells using flow cytometry

Methods (San Diego, Calif.), 2012-03, Vol.56 (3), p.375-382

2012

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Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells

Applied microbiology and biotechnology, 2014-06, Vol.98 (12), p.5417-5425

2014

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Effect of inducible co-overexpression of protein disulfide isomerase and endoplasmic reticulum oxidoreductase on the specific antibody productivity of recombinant Chinese hamster ovary cells

Biotechnology and bioengineering, 2010-10, Vol.107 (2), p.337-346

2010

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Comprehensive characterization of glutamine synthetase-mediated selection for the establishment of recombinant CHO cells producing monoclonal antibodies

Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions

Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion

Accelerated homology-directed targeted integration of transgenes in Chinese hamster ovary cells via CRISPR/Cas9 and fluorescent enrichment

Multiplex secretome engineering enhances recombinant protein production and purity

Cell Culture Engineering: Recombinant Protein Production

Selective endocytosis of recombinant human BMPs through cell surface heparan sulfate proteoglycans in CHO cells: BMP-2 and BMP-7

Understanding of decreased sialylation of Fc‐fusion protein in hyperosmotic recombinant Chinese hamster ovary cell culture: N‐glycosylation gene expression and N‐linked glycan antennary profile

Amplification of EBNA-1 through a single-plasmid vector-based gene amplification system in HEK293 cells as an efficient transient gene expression system

Effect of lithium chloride on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture

The molecular weight and concentration of dextran sulfate affect cell growth and antibody production in CHO cell cultures

Limitations to the development of recombinant human embryonic kidney 293E cells using glutamine synthetase-mediated gene amplification: Methionine sulfoximine resistance

CHO cells in biotechnology for production of recombinant proteins: current state and further potential

Investigation of relationship between EBNA-1 expression level and specific foreign protein productivity in transient gene expression of HEK293 cells

Effect of glucose feeding on the glycosylation quality of antibody produced by a human cell line, F2N78, in fed-batch culture

Mitigating Clonal Variation in Recombinant Mammalian Cell Lines

Effect of culture pH on erythropoietin production by Chinese hamster ovary cells grown in suspension at 32.5 and 37.0°C

Electrospun chitosan/poly(vinyl alcohol) reinforced with CaCO3 nanoparticles with enhanced mechanical properties and biocompatibility for cartilage tissue engineering

Untangling the mechanism of 3‐methyladenine in enhancing the specific productivity: Transcriptome analysis of recombinant Chinese hamster ovary cells treated with 3‐methyladenine

Effect of glutamine substitution by TCA cycle intermediates on the production and sialylation of Fc-fusion protein in Chinese hamster ovary cell culture

Anti-Apoptosis Engineering for Improved Protein Production from CHO Cells

Analysis of Golgi pH in Chinese hamster ovary cells using ratiometric pH‐sensitive fluorescent proteins

Monitoring of autophagy in Chinese hamster ovary cells using flow cytometry

Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells

Effect of inducible co-overexpression of protein disulfide isomerase and endoplasmic reticulum oxidoreductase on the specific antibody productivity of recombinant Chinese hamster ovary cells

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