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RET signaling in breast cancer therapeutic resistance and metastasis

Breast cancer research : BCR, 2023-03, Vol.25 (1), p.26-26, Article 26

2023

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The Cellular Origin and Evolution of Breast Cancer

Cold Spring Harbor perspectives in medicine, 2017-03, Vol.7 (3), p.a027128

2017

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Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis

Clinical cancer research, 2019-06, Vol.25 (12), p.3479-3485

2019

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Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities

Nature communications, 2022-01, Vol.13 (1), p.514-514, Article 514

2022

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Mixed invasive ductal lobular carcinoma is clinically and pathologically more similar to invasive lobular than ductal carcinoma

British journal of cancer, 2023-04, Vol.128 (6), p.1030-1039

2023

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Comprehensive evaluation of fusion transcript detection algorithms and a meta-caller to combine top performing methods in paired-end RNA-seq data

Nucleic acids research, 2016-03, Vol.44 (5), p.e47-e47

2016

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Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models

Breast cancer research : BCR, 2017-05, Vol.19 (1), p.60-60, Article 60

2017

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Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism

Scientific reports, 2018-05, Vol.8 (1), p.7205-11, Article 7205

2018

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Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients

Clinical cancer research, 2016-03, Vol.22 (5), p.1130-1137

2016

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Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors

Clinical cancer research, 2018-10, Vol.24 (20), p.5165-5177

2018

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iGenSig-Rx: an integral genomic signature based white-box tool for modeling cancer therapeutic responses using multi-omics data

BMC bioinformatics, 2024-06, Vol.25 (1), p.220-17, Article 220

2024

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The IGF Pathway Regulates ERα through a S6K1-Dependent Mechanism in Breast Cancer Cells

Molecular endocrinology (Baltimore, Md.), 2011-03, Vol.25 (3), p.516-528

2011

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Systems approach for congruence and selection of cancer models towards precision medicine

PLoS computational biology, 2024-01, Vol.20 (1), p.e1011754-e1011754

2024

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ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation

Nature communications, 2022-04, Vol.13 (1), p.2011-2011, Article 2011

2022

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Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

PLoS genetics, 2022-09, Vol.18 (9), p.e1010122-e1010122

2022

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Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

Molecular cancer research, 2022-09, Vol.20 (9), p.1405-1419

2022

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Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types

Cell reports (Cambridge), 2016-11, Vol.17 (8), p.2075-2086

2016

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Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

Cancer cell, 2009-06, Vol.15 (6), p.539-550

2009

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Precision Medicine in Hormone Receptor-Positive Breast Cancer

Frontiers in oncology, 2018-05, Vol.8, p.144-144

2018

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TCGA Expedition: A Data Acquisition and Management System for TCGA Data

PloS one, 2016-10, Vol.11 (10), p.e0165395-e0165395

2016

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Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis

Journal of clinical oncology, 2008-09, Vol.26 (25), p.4078-4085

2008

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Biology of Progesterone Receptor Loss in Breast Cancer and Its Implications for Endocrine Therapy

Journal of clinical oncology, 2005-10, Vol.23 (30), p.7721-7735

2005

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Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences

Breast cancer research : BCR, 2021-01, Vol.23 (1), p.1-1, Article 1

2021

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Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised

eLife, 2021-06, Vol.10

2021

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Proteomic and transcriptomic profiling identifies mediators of anchorage-independent growth and roles of inhibitor of differentiation proteins in invasive lobular carcinoma

Scientific reports, 2020-07, Vol.10 (1), p.11487-11487, Article 11487

2020

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RET signaling in breast cancer therapeutic resistance and metastasis

The Cellular Origin and Evolution of Breast Cancer

Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis

Mapping molecular subtype specific alterations in breast cancer brain metastases identifies clinically relevant vulnerabilities

Mixed invasive ductal lobular carcinoma is clinically and pathologically more similar to invasive lobular than ductal carcinoma

Comprehensive evaluation of fusion transcript detection algorithms and a meta-caller to combine top performing methods in paired-end RNA-seq data

Mutation site and context dependent effects of ESR1 mutation in genome-edited breast cancer cell models

Invasive lobular and ductal breast carcinoma differ in immune response, protein translation efficiency and metabolism

Sensitive Detection of Mono- and Polyclonal ESR1 Mutations in Primary Tumors, Metastatic Lesions, and Cell-Free DNA of Breast Cancer Patients

Loss of E-cadherin Enhances IGF1-IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR Inhibitors

iGenSig-Rx: an integral genomic signature based white-box tool for modeling cancer therapeutic responses using multi-omics data

The IGF Pathway Regulates ERα through a S6K1-Dependent Mechanism in Breast Cancer Cells

Systems approach for congruence and selection of cancer models towards precision medicine

ESR1 mutant breast cancers show elevated basal cytokeratins and immune activation

Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer

Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma

Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types

Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

Precision Medicine in Hormone Receptor-Positive Breast Cancer

TCGA Expedition: A Data Acquisition and Management System for TCGA Data

Insulin-Like Growth Factor-I Activates Gene Transcription Programs Strongly Associated With Poor Breast Cancer Prognosis

Biology of Progesterone Receptor Loss in Breast Cancer and Its Implications for Endocrine Therapy

Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences

Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised

Proteomic and transcriptomic profiling identifies mediators of anchorage-independent growth and roles of inhibitor of differentiation proteins in invasive lobular carcinoma

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