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Artificial intelligence–guided precision treatment of chronic kidney disease–mineral bone disorder

CPT: pharmacometrics and systems pharmacology, 2022-10, Vol.11 (10), p.1305-1315

2022

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NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormones

American journal of physiology. Renal physiology, 2012-08, Vol.303 (3), p.F321-F327

2012

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Aldosterone regulates Na+, K+ ATPase activity in human renal proximal tubule cells through mineralocorticoid receptor

Biochimica et biophysica acta, 2013-10, Vol.1833 (10), p.2143-2152

2013

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Use of Artificial Intelligence to Identify New Mechanisms and Approaches to Therapy of Bone Disorders Associated With Chronic Kidney Disease

Frontiers in medicine, 2022-03, Vol.9, p.807994-807994

2022

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Kidney Stone Pathophysiology, Evaluation and Management: Core Curriculum 2023

American journal of kidney diseases, 2023-11, Vol.82 (5), p.617-634

2023

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Phosphorus: Chronicles of the epistemology of a vital element

Clinical nephrology, 2024-09, Vol.102 (3), p.117-124

2024

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PTH-mediated inhibition of the renal transport of phosphate

Experimental cell research, 2012-05, Vol.318 (9), p.1027-1032

2012

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Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators

PloS one, 2015-04, Vol.10 (4), p.e0121637

2015

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Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells

American Journal of Physiology - Renal Physiology, 2010-07, Vol.299 (1), p.F77-F90

2010

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Transcriptomes of Major Proximal Tubule Cell Culture Models

Journal of the American Society of Nephrology, 2021-01, Vol.32 (1), p.86-97

2021

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Proteomic analysis of renal calculi indicates an important role for inflammatory processes in calcium stone formation

American Journal of Physiology - Renal Physiology, 2008-10, Vol.295 (4), p.F1254-F1258

2008

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Cancer Therapy in a Data Vacuum

Diseases of the colon & rectum, 2021-12, Vol.64 (12), p.1441-1443

2021

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New roles of the Na + /H + exchange regulatory factor 1 scaffolding protein: a review

American journal of physiology. Regulatory, integrative and comparative physiology, 2020-03, Vol.318 (3), p.F804-F808

2020

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Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

Antioxidants, 2021-06, Vol.10 (7), p.1036

2021

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Protein-DNA Interactions at the Opossum Npt2a Promoter are Dependent upon NHERF-1

Cellular physiology and biochemistry, 2016-01, Vol.39 (1), p.1-12

2016

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Development of a quantitative systems pharmacology model of chronic kidney disease: metabolic bone disorder

American journal of physiology. Renal physiology, 2021-02, Vol.320 (2), p.F203-F211

2021

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Kidney Injury Stimulates Apical Translocation of NHERF1

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Na+/H+ Exchanger-Regulatory Factor 1 Mediates Inhibition of Phosphate Transport by Parathyroid Hormone and Second Messengers by Acting at Multiple Sites in Opossum Kidney Cells

Molecular endocrinology (Baltimore, Md.), 2003-11, Vol.17 (11), p.2355-2364

2003

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Application of artificial intelligence to chronic kidney disease mineral bone disorder

Clinical kidney journal, 2024-06, Vol.17 (6), p.sfae143

2024

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Sodium-hydrogen exchanger regulatory factor-1 (NHERF1) confers salt sensitivity in both male and female models of hypertension in aging

Life sciences (1973), 2020-02, Vol.243, p.117226-117226, Article 117226

2020

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Novel regulatory function for NHERF-1 in Npt2a transcription

American journal of physiology. Renal physiology, 2008-04, Vol.294 (4), p.F840-F849

2008

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Role of PTH in the Renal Handling of Phosphate

AIMS medical science, 2015-01, Vol.2 (3), p.162-181

2015

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Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury

The American journal of pathology, 2019-06, Vol.189 (6), p.1190-1200

2019

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Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA

American Journal of Physiology: Cell Physiology, 2016-02, Vol.310 (3), p.C205-C215

2016

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Parathyroid Hormone Regulation of Type II Sodium-Phosphate Cotransporters Is Dependent on an A Kinase Anchoring Protein

The Journal of biological chemistry, 2003-03, Vol.278 (12), p.10134-10141

2003

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Artificial intelligence–guided precision treatment of chronic kidney disease–mineral bone disorder

NHERF-1 and the regulation of renal phosphate reabsoption: a tale of three hormones

Aldosterone regulates Na+, K+ ATPase activity in human renal proximal tubule cells through mineralocorticoid receptor

Use of Artificial Intelligence to Identify New Mechanisms and Approaches to Therapy of Bone Disorders Associated With Chronic Kidney Disease

Kidney Stone Pathophysiology, Evaluation and Management: Core Curriculum 2023

Phosphorus: Chronicles of the epistemology of a vital element

PTH-mediated inhibition of the renal transport of phosphate

Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators

Ouabain stimulates Na-K-ATPase through a sodium/hydrogen exchanger-1 (NHE-1)-dependent mechanism in human kidney proximal tubule cells

Transcriptomes of Major Proximal Tubule Cell Culture Models

Proteomic analysis of renal calculi indicates an important role for inflammatory processes in calcium stone formation

Cancer Therapy in a Data Vacuum

New roles of the Na + /H + exchange regulatory factor 1 scaffolding protein: a review

Na/H Exchange Regulatory Factor 1 Deficient Mice Show Evidence of Oxidative Stress and Altered Cisplatin Pharmacokinetics

Protein-DNA Interactions at the Opossum Npt2a Promoter are Dependent upon NHERF-1

Development of a quantitative systems pharmacology model of chronic kidney disease: metabolic bone disorder

Kidney Injury Stimulates Apical Translocation of NHERF1

Na+/H+ Exchanger-Regulatory Factor 1 Mediates Inhibition of Phosphate Transport by Parathyroid Hormone and Second Messengers by Acting at Multiple Sites in Opossum Kidney Cells

Application of artificial intelligence to chronic kidney disease mineral bone disorder

Sodium-hydrogen exchanger regulatory factor-1 (NHERF1) confers salt sensitivity in both male and female models of hypertension in aging

Novel regulatory function for NHERF-1 in Npt2a transcription

Role of PTH in the Renal Handling of Phosphate

Loss of the Na+/H+ Exchange Regulatory Factor 1 Increases Susceptibility to Cisplatin-Induced Acute Kidney Injury

Identification of an RNA-binding protein that is phosphorylated by PTH and potentially mediates PTH-induced destabilization of Npt2a mRNA

Parathyroid Hormone Regulation of Type II Sodium-Phosphate Cotransporters Is Dependent on an A Kinase Anchoring Protein

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