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Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury

PloS one, 2013-08, Vol.8 (8), p.e70464-e70464

2013

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Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models

Nature medicine, 2010-07, Vol.16 (7), p.788-792

2010

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A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis

Kidney international, 2011-06, Vol.79 (11), p.1236-1243

2011

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CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis

American journal of physiology. Renal physiology, 2016-06, Vol.310 (11), p.F1414-F1422

2016

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CXA-10, a Nitrated Fatty Acid, Is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy

The Journal of pharmacology and experimental therapeutics, 2019-06, Vol.369 (3), p.503

2019

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Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis

Human molecular genetics, 2016-06, Vol.25 (11), p.2245-2255

2016

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Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine

Nature, 2006-12, Vol.444 (7121), p.949-952

2006

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CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

Cell cycle (Georgetown, Tex.), 2012-11, Vol.11 (21), p.4040-4046

2012

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A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis

Kidney international reports, 2017-09, Vol.2 (5), p.800-810

2017

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Role of TGF‐β in a Mouse Model of High Turnover Renal Osteodystrophy

Journal of bone and mineral research, 2014-05, Vol.29 (5), p.1141-1157

2014

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Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease

Human molecular genetics, 2012-08, Vol.21 (15), p.3397-3407

2012

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Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury

Kidney international, 2009-03, Vol.75 (5), p.511-517

2009

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Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats

American journal of physiology. Regulatory, integrative and comparative physiology, 2012-07, Vol.303 (1), p.R57-R69

2012

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Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

Nature medicine, 1998-06, Vol.4 (6), p.691-697

1998

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Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction

American journal of physiology. Renal physiology, 2007-04, Vol.292 (4), p.F1291-F1301

2007

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Transforming Growth Factor-β, 20-HETE Interaction, and Glomerular Injury in Dahl Salt-Sensitive Rats

Hypertension (Dallas, Tex. 1979), 2005-04, Vol.45 (4, Part 2 Suppl), p.643-648

2005

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Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD

Physiological reports, 2016-06, Vol.4 (12), p.e12846-n/a

2016

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Antihypertensive effects of chronic anti-TGF-beta antibody therapy in Dahl S rats

American journal of physiology. Regulatory, integrative and comparative physiology, 2002-09, Vol.283 (3), p.757-R767

2002

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Repression of osteocyte Wnt/β-catenin signaling is an early event in the progression of renal osteodystrophy

Journal of bone and mineral research, 2012-08, Vol.27 (8), p.1757-1772

2012

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Perlecan is a component of cartilage matrix and promotes chondrocyte attachment

Journal of cell science, 1995-07, Vol.108 ( Pt 7) (7), p.2663-2672

1995

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Npt2b Deletion Attenuates Hyperphosphatemia Associated with CKD

Journal of the American Society of Nephrology, 2012-10, Vol.23 (10), p.1691-1700

2012

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Glomerulopathy in the KK.Cg-Ay/J Mouse Reflects the Pathology of Diabetic Nephropathy

Journal of diabetes research, 2013-01, Vol.2013

2013

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Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence

The Journal of experimental medicine, 2003-12, Vol.198 (11), p.1741-1752

2003

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The Temporal Effects of Anti-TGF-β1, 2, and 3 Monoclonal Antibody on Wound Healing and Hypertrophic Scar Formation

Journal of the American College of Surgeons, 2005-09, Vol.201 (3), p.391-397

2005

Volltextzugriff (PDF)

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Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury

Blocking TGF-β Signaling Pathway Preserves Mitochondrial Proteostasis and Reduces Early Activation of PDGFRβ+ Pericytes in Aristolochic Acid Induced Acute Kidney Injury in Wistar Male Rats

Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models

A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis

CaMKII as a pathological mediator of ER stress, oxidative stress, and mitochondrial dysfunction in a murine model of nephronophthisis

CXA-10, a Nitrated Fatty Acid, Is Renoprotective in Deoxycorticosterone Acetate-Salt Nephropathy

Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis

Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine

CDK inhibitors R-roscovitine and S-CR8 effectively block renal and hepatic cystogenesis in an orthologous model of ADPKD

A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis

Role of TGF‐β in a Mouse Model of High Turnover Renal Osteodystrophy

Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease

Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury

Renoprotective effects of anti-TGF-β antibody and antihypertensive therapies in Dahl S rats

Physiological degradation converts the soluble syndecan-1 ectodomain from an inhibitor to a potent activator of FGF-2

Effect of combination therapy with enalapril and the TGF-beta antagonist 1D11 in unilateral ureteral obstruction

Transforming Growth Factor-β, 20-HETE Interaction, and Glomerular Injury in Dahl Salt-Sensitive Rats

Differences in the timing and magnitude of Pkd1 gene deletion determine the severity of polycystic kidney disease in an orthologous mouse model of ADPKD

Antihypertensive effects of chronic anti-TGF-beta antibody therapy in Dahl S rats

Repression of osteocyte Wnt/β-catenin signaling is an early event in the progression of renal osteodystrophy

Perlecan is a component of cartilage matrix and promotes chondrocyte attachment

Npt2b Deletion Attenuates Hyperphosphatemia Associated with CKD

Glomerulopathy in the KK.Cg-Ay/J Mouse Reflects the Pathology of Diabetic Nephropathy

Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence

The Temporal Effects of Anti-TGF-β1, 2, and 3 Monoclonal Antibody on Wound Healing and Hypertrophic Scar Formation

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