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Sequence features of variable region determining physicochemical properties and polyreactivity of therapeutic antibodies

Molecular immunology, 2019-08, Vol.112, p.338-346

2019

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Polyreactivity of antibodies from different B-cell subpopulations is determined by distinct sequence patterns of variable region

Frontiers in immunology, 2023-11, Vol.14, p.1266668-1266668

2023

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Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities

Communications biology, 2021-03, Vol.4 (1), p.391-391, Article 391

2021

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Temperature sensitivity of bat antibodies links metabolic state of bats with antigen-recognition diversity

Nature communications, 2024-07, Vol.15 (1), p.5878-19, Article 5878

2024

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Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy

Cell death & disease, 2020-01, Vol.11 (1), p.50-50, Article 50

2020

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Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies

International journal of molecular sciences, 2023-02, Vol.24 (4), p.3416

2023

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Induced antigen-binding polyreactivity in human serum IgA

Immunobiology (1979), 2022-05, Vol.227 (3), p.152213-152213, Article 152213

2022

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Functional Changes of Therapeutic Antibodies upon Exposure to Pro-Oxidative Agents

Antibodies (Basel), 2022-02, Vol.11 (1), p.11

2022

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Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance

Frontiers in immunology, 2020-05, Vol.11, p.810-810

2020

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Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity

The Journal of biological chemistry, 2015-02, Vol.290 (8), p.5203-5213

2015

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Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

Communications biology, 2023-02, Vol.6 (1), p.168-168, Article 168

2023

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Functional Analysis of AtlA, the Major N-Acetylglucosaminidase of Enterococcus faecalis

Journal of Bacteriology, 2006-12, Vol.188 (24), p.8513-8519

2006

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Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

Scientific reports, 2015-11, Vol.5 (1), p.16248-16248, Article 16248

2015

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Efficient Access to Peptidyl-RNA Conjugates for Picomolar Inhibition of Non-ribosomal FemXWv Aminoacyl Transferase

Chemistry : a European journal, 2013-01, Vol.19 (4), p.1357-1363

2013

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Clinical and Autoimmune Profile of Scleroderma Patients from Western India

International Journal of Rheumatology, 2014-01, Vol.2014 (2014), p.u1-6

2014

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Hemolysis and Free Heme Impact Therapeutic Activity of Anti-CD20 Antibody

Blood, 2023-11, Vol.142 (Supplement 1), p.6129-6129

2023

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Aromatic Guanylhydrazones for the Control of Heme-Induced Antibody Polyreactivity

ACS omega, 2019-12, Vol.4 (24), p.20450-20458

2019

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Decoding the Logic of the tRNA Regiospecificity of Nonribosomal FemXWv Aminoacyl Transferase

Angewandte Chemie (International ed.), 2010-07, Vol.49 (30), p.5115-5119

2010

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Method for identification of heme-binding proteins and quantification of their interactions

Analytical biochemistry, 2020-10, Vol.607, p.113865-113865, Article 113865

2020

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V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor

The Journal of immunology (1950), 2020-11, Vol.205 (10), p.2850-2860

2020

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Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins: implication for microbicide development

Journal of translational medicine, 2007-06, Vol.5 (1), p.28-28, Article 28

2007

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Interaction with 2,4-dinitrophenol correlates with polyreactivity, self-binding, and stability of clinical-stage therapeutic antibodies

Molecular immunology, 2021-12, Vol.140, p.233-239

2021

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Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy

Journal of thrombosis and haemostasis, 2023-06

2023

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Use of cysteine as a spectroscopic probe for determination of heme-scavenging capacity of serum proteins and whole human serum

Journal of pharmaceutical and biomedical analysis, 2019-08, Vol.172, p.311-319

2019

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Transplacental delivery of therapeutic proteins by engineered immunoglobulin G: a step toward perinatal replacement therapy

Journal of thrombosis and haemostasis, 2023-09, Vol.21 (9), p.2405-2417

2023

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Sequence features of variable region determining physicochemical properties and polyreactivity of therapeutic antibodies

Polyreactivity of antibodies from different B-cell subpopulations is determined by distinct sequence patterns of variable region

Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities

Temperature sensitivity of bat antibodies links metabolic state of bats with antigen-recognition diversity

Intravenous immunoglobulin mediates anti-inflammatory effects in peripheral blood mononuclear cells by inducing autophagy

Hyperoxidized Species of Heme Have a Potent Capacity to Induce Autoreactivity of Human IgG Antibodies

Induced antigen-binding polyreactivity in human serum IgA

Functional Changes of Therapeutic Antibodies upon Exposure to Pro-Oxidative Agents

Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance

Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity

Oxidized hemoglobin triggers polyreactivity and autoreactivity of human IgG via transfer of heme

Functional Analysis of AtlA, the Major N-Acetylglucosaminidase of Enterococcus faecalis

Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody

Efficient Access to Peptidyl-RNA Conjugates for Picomolar Inhibition of Non-ribosomal FemXWv Aminoacyl Transferase

Clinical and Autoimmune Profile of Scleroderma Patients from Western India

Hemolysis and Free Heme Impact Therapeutic Activity of Anti-CD20 Antibody

Aromatic Guanylhydrazones for the Control of Heme-Induced Antibody Polyreactivity

Decoding the Logic of the tRNA Regiospecificity of Nonribosomal FemXWv Aminoacyl Transferase

Method for identification of heme-binding proteins and quantification of their interactions

V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor

Differential in vitro inhibitory activity against HIV-1 of alpha-(1-3)- and alpha-(1-6)-D-mannose specific plant lectins: implication for microbicide development

Interaction with 2,4-dinitrophenol correlates with polyreactivity, self-binding, and stability of clinical-stage therapeutic antibodies

Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy

Use of cysteine as a spectroscopic probe for determination of heme-scavenging capacity of serum proteins and whole human serum

Transplacental delivery of therapeutic proteins by engineered immunoglobulin G: a step toward perinatal replacement therapy

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