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Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial

Neurology, 2005-07, Vol.65 (2), p.286-292

2005

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A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease

Nature neuroscience, 2015-06, Vol.18 (6), p.807-816

2015

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Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

Nature genetics, 2003-09, Vol.35 (1), p.76-83

2003

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Induction of neurogenesis in the neocortex of adult mice

Nature (London), 2000-06, Vol.405 (6789), p.951-955

2000

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Progranulin expression in the developing and adult murine brain

Journal of comparative neurology (1911), 2010-10, Vol.518 (19), p.3931-3947

2010

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Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines

Nature neuroscience, 2002-08, Vol.5 (8), p.731-736

2002

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Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

Science (American Association for the Advancement of Science), 2001-07, Vol.293 (5529), p.493-498

2001

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Cognitive Dysfunction Precedes Neuropathology and Motor Abnormalities in the YAC128 Mouse Model of Huntington's Disease

The Journal of neuroscience, 2005-04, Vol.25 (16), p.4169-4180

2005

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Absence of Behavioral Abnormalities and Neurodegeneration in vivo despite Widespread Neuronal Huntingtin Inclusions

Proceedings of the National Academy of Sciences - PNAS, 2005-08, Vol.102 (32), p.11402-11407

2005

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Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

Human molecular genetics, 2003-07, Vol.12 (13), p.1555-1567

2003

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Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease

Neuron (Cambridge, Mass.), 2002-03, Vol.33 (6), p.849-860

2002

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Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease

Human molecular genetics, 2005-12, Vol.14 (24), p.3823-3835

2005

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Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY‐cleaving peptidases and potential drug interactions in CNS and Periphery

Journal of neurochemistry, 2015-12, Vol.135 (5), p.1019-1037

2015

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Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease

The Journal of neuroscience, 2002-09, Vol.22 (18), p.7862-7872

2002

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Wild‐type huntingtin protects neurons from excitotoxicity

Journal of neurochemistry, 2006-02, Vol.96 (4), p.1121-1129

2006

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Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease

Human molecular genetics, 2005-05, Vol.14 (10), p.1379-1392

2005

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Expression analysis of novel striatal-enriched genes in Huntington disease

Human molecular genetics, 2010-02, Vol.19 (4), p.609-622

2010

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Body weight is modulated by levels of full-length Huntingtin

Human molecular genetics, 2006-05, Vol.15 (9), p.1513-1523

2006

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A one-hit model of cell death in inherited neuronal degenerations

Nature (London), 2000-07, Vol.406 (6792), p.195-199

2000

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A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

Neuron (Cambridge, Mass.), 1999-05, Vol.23 (1), p.181-192

1999

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Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

Cell death and differentiation, 2004-04, Vol.11 (4), p.424-438

2004

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NMDA receptor function in mouse models of Huntington disease

Journal of neuroscience research, 2001-11, Vol.66 (4), p.525-539

2001

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Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease

Journal of neurochemistry, 2005-10, Vol.95 (1), p.210-220

2005

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Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

Neurobiology of disease, 2006-02, Vol.21 (2), p.392-403

2006

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Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

Molecular and cellular neuroscience, 2004-03, Vol.25 (3), p.469-479

2004

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Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial

A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

Induction of neurogenesis in the neocortex of adult mice

Progranulin expression in the developing and adult murine brain

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines

Loss of Huntingtin-Mediated BDNF Gene Transcription in Huntington's Disease

Cognitive Dysfunction Precedes Neuropathology and Motor Abnormalities in the YAC128 Mouse Model of Huntington's Disease

Absence of Behavioral Abnormalities and Neurodegeneration in vivo despite Widespread Neuronal Huntingtin Inclusions

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

Increased Sensitivity to N-Methyl-D-Aspartate Receptor-Mediated Excitotoxicity in a Mouse Model of Huntington's Disease

Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease

Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY‐cleaving peptidases and potential drug interactions in CNS and Periphery

Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease

Wild‐type huntingtin protects neurons from excitotoxicity

Loss of wild-type huntingtin influences motor dysfunction and survival in the YAC128 mouse model of Huntington disease

Expression analysis of novel striatal-enriched genes in Huntington disease

Body weight is modulated by levels of full-length Huntingtin

A one-hit model of cell death in inherited neuronal degenerations

A YAC Mouse Model for Huntington’s Disease with Full-Length Mutant Huntingtin, Cytoplasmic Toxicity, and Selective Striatal Neurodegeneration

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

NMDA receptor function in mouse models of Huntington disease

Cystamine treatment is neuroprotective in the YAC128 mouse model of Huntington disease

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

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