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KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells

Oncotarget, 2017-05, Vol.8 (20), p.32833-32847

2017

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Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity

PloS one, 2011-11, Vol.6 (11), p.e27723

2011

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Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential

IUBMB life, 2016-04, Vol.68 (4), p.268-280

2016

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The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

International journal of cancer, 2009-04, Vol.124 (8), p.1829-1840

2009

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Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic

Molecular cancer therapeutics, 2016-04, Vol.15 (4), p.560-573

2016

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Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer

BMC cancer, 2021-02, Vol.21 (1), p.106-106, Article 106

2021

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A mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells

Scientific reports, 2022-11, Vol.12 (1), p.20171-20171, Article 20171

2022

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Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells

Carcinogenesis (New York), 2014-05, Vol.35 (5), p.1121-1131

2014

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A tight balance of Karyopherin β1 expression is required in cervical cancer cells

BMC cancer, 2018-11, Vol.18 (1), p.1123-1123, Article 1123

2018

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Absence of feedback regulation in the synthesis of COL1A1

Life sciences (1973), 2014-05, Vol.103 (1), p.25-33

2014

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PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration

Biochemical journal, 2011-01, Vol.433 (1), p.145-153

2011

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The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage

Biochimica et biophysica acta, 2011-07, Vol.1809 (7), p.316-326

2011

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p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts

PloS one, 2013-06, Vol.8 (6), p.e66892-e66892

2013

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Feedback regulation of the α2(1) collagen gene via the Mek–Erk signaling pathway

IUBMB life, 2012-01, Vol.64 (1), p.87-98

2012

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Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy

IUBMB life, 2024-01, Vol.76 (1), p.4-25

2024

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Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells

Experimental cell research, 2021-07, Vol.404 (2), p.112637-112637, Article 112637

2021

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Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers

International journal of cancer, 2022-01, Vol.150 (2), p.347-361

2022

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Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes

Molecular cancer research, 2020-09, Vol.18 (9), p.1340-1353

2020

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The tumour suppressing role of the circadian clock

IUBMB life, 2019-07, Vol.71 (7), p.771-780

2019

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The Karyopherin proteins, Crm1 and Karyopherin beta 1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

International journal of cancer, 2009-04, Vol.124 (8), p.1829-1840

2009

Volltextzugriff (PDF)

Reactive oxygen species mediated apoptosis of esophageal cancer cells induced by marine triprenyl toluquinones and toluhydroquinones

Molecular cancer therapeutics, 2007-09, Vol.6 (9), p.2535-2543

2007

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The nuclear import receptor Kpnβ1 and its potential as an anticancer therapeutic target

Critical reviews in eukaryotic gene expression, 2013, Vol.23 (1), p.1-10

2013

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Interfering with Nuclear Transport as a Means of Interrupting Transcription Factor Activity in Cancer

Critical reviews in eukaryotic gene expression, 2019, Vol.29 (5), p.413-424

2019

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Cyclin A Is a c-Jun Target Gene and Is Necessary for c-Jun-induced Anchorage-independent Growth in RAT1a Cells

The Journal of biological chemistry, 2005-04, Vol.280 (17), p.16728-16738

2005

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Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma

Oncology reports, 2014-08, Vol.32 (2), p.730-738

2014

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KPNB1-mediated nuclear import is required for motility and inflammatory transcription factor activity in cervical cancer cells

Overexpression of Kpnβ1 and Kpnα2 importin proteins in cancer derives from deregulated E2F activity

Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential

The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic

Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer

A mass spectrometry-based approach for the identification of Kpnβ1 binding partners in cancer cells

Inhibition of the nuclear transporter, Kpnβ1, results in prolonged mitotic arrest and activation of the intrinsic apoptotic pathway in cervical cancer cells

A tight balance of Karyopherin β1 expression is required in cervical cancer cells

Absence of feedback regulation in the synthesis of COL1A1

PMA-induced up-regulation of TBX3 is mediated by AP-1 and contributes to breast cancer cell migration

The nuclear exporter, Crm1, is regulated by NFY and Sp1 in cancer cells and repressed by p53 in response to DNA damage

p21-activated kinase 3 (PAK3) is an AP-1 regulated gene contributing to actin organisation and migration of transformed fibroblasts

Feedback regulation of the α2(1) collagen gene via the Mek–Erk signaling pathway

Therapeutic targeting of nuclear export and import receptors in cancer and their potential in combination chemotherapy

Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells

Nuclear transport proteins are secreted by cancer cells and identified as potential novel cancer biomarkers

Circadian Oscillations Persist in Cervical and Esophageal Cancer Cells Displaying Decreased Expression of Tumor-Suppressing Circadian Clock Genes

The tumour suppressing role of the circadian clock

The Karyopherin proteins, Crm1 and Karyopherin beta 1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation

Reactive oxygen species mediated apoptosis of esophageal cancer cells induced by marine triprenyl toluquinones and toluhydroquinones

The nuclear import receptor Kpnβ1 and its potential as an anticancer therapeutic target

Interfering with Nuclear Transport as a Means of Interrupting Transcription Factor Activity in Cancer

Cyclin A Is a c-Jun Target Gene and Is Necessary for c-Jun-induced Anchorage-independent Growth in RAT1a Cells

Elevated expression of the nuclear export protein, Crm1 (exportin 1), associates with human oesophageal squamous cell carcinoma

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