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Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics

Gastroenterology (New York, N.Y. 1943), 2006-05, Vol.130 (6), p.1793-1806

2006

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Identification and Characterization of Trimethylamine‑N‑oxide Uptake and Efflux Transporters

Molecular pharmaceutics, 2017-01, Vol.14 (1), p.310-318

2017

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Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

Circulation research, 2010-02, Vol.106 (2), p.297-306

2010

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Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance

Molecular pharmacology, 2017-01, Vol.91 (1), p.14-24

2017

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Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

The Journal of pharmacology and experimental therapeutics, 2003-01, Vol.304 (1), p.223

2003

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Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry

The Journal of biological chemistry, 2005-03, Vol.280 (10), p.9610-9617

2005

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Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity

Pharmacogenetics and genomics, 2011-03, Vol.21 (3), p.103-114

2011

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Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

Clinical pharmacology and therapeutics, 2002-01, Vol.71 (1), p.11-20

2002

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Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance

Molecular cancer therapeutics, 2015-04, Vol.14 (4), p.994-1003

2015

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Ethnicity-dependent Polymorphism in Na+-taurocholate Cotransporting Polypeptide (SLC10A1) Reveals a Domain Critical for Bile Acid Substrate Recognition

The Journal of biological chemistry, 2004-02, Vol.279 (8), p.7213-7222

2004

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Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe

Pharmacogenetics and genomics, 2008-05, Vol.18 (5), p.439-448

2008

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The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

Nature medicine, 2003-02, Vol.9 (2), p.220-224

2003

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Mouse NTCP–Mediated Rosuvastatin Uptake In Vitro and in Slc10a1-Deficient Mice

The AAPS journal, 2021-01, Vol.23 (1), p.17-17, Article 17

2021

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Identification of functionally variant MDR1 alleles among European Americans and African Americans

Clinical pharmacology and therapeutics, 2001-08, Vol.70 (2), p.189-199

2001

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Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability

Pharmacogenetics and genomics, 2010-01, Vol.20 (1), p.45-57

2010

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OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

Drug metabolism and disposition, 1999-08, Vol.27 (8), p.866

1999

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Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes

The Journal of pharmacology and experimental therapeutics, 2006-09, Vol.318 (3), p.1068

2006

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An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1

Molecular pharmacology, 2013-02, Vol.83 (2), p.481-489

2013

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Interaction of Three Regiospecific Amino Acid Residues Is Required for OATP1B1 Gain of OATP1B3 Substrate Specificity

Molecular pharmaceutics, 2012-04, Vol.9 (4), p.986-995

2012

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Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Molecular pharmacology, 2002-05, Vol.61 (5), p.974-981

2002

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Hepatic uptake of the novel antifungal agent caspofungin

Drug metabolism and disposition, 2005-05, Vol.33 (5), p.676

2005

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Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

Molecular pharmacology, 2002-05, Vol.61 (5), p.964-973

2002

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Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes

Drug metabolism and disposition, 2000-06, Vol.28 (6), p.655

2000

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A Common Polymorphism in the Bile Acid Receptor Farnesoid X Receptor Is Associated with Decreased Hepatic Target Gene Expression

Molecular endocrinology (Baltimore, Md.), 2007-08, Vol.21 (8), p.1769-1780

2007

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Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2)

Journal of gastroenterology and hepatology, 2011-12, Vol.26 (12), p.1740-1748

2011

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Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics

Identification and Characterization of Trimethylamine‑N‑oxide Uptake and Efflux Transporters

Human Skeletal Muscle Drug Transporters Determine Local Exposure and Toxicity of Statins

Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry

Identification of novel functional organic anion-transporting polypeptide 1B3 polymorphisms and assessment of substrate specificity

Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine

Contribution of hepatic organic anion-transporting polypeptides to docetaxel uptake and clearance

Ethnicity-dependent Polymorphism in Na+-taurocholate Cotransporting Polypeptide (SLC10A1) Reveals a Domain Critical for Bile Acid Substrate Recognition

Breast cancer resistance protein (ABCG2) and drug disposition: intestinal expression, polymorphisms and sulfasalazine as an in vivo probe

The orphan nuclear receptor HNF4α determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

Mouse NTCP–Mediated Rosuvastatin Uptake In Vitro and in Slc10a1-Deficient Mice

Identification of functionally variant MDR1 alleles among European Americans and African Americans

Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability

OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine

Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes

An allosteric mechanism for drug block of the human cardiac potassium channel KCNQ1

Interaction of Three Regiospecific Amino Acid Residues Is Required for OATP1B1 Gain of OATP1B3 Substrate Specificity

Application of Three-Dimensional Quantitative Structure-Activity Relationships of P-Glycoprotein Inhibitors and Substrates

Hepatic uptake of the novel antifungal agent caspofungin

Three-Dimensional Quantitative Structure-Activity Relationships of Inhibitors of P-Glycoprotein

Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes

A Common Polymorphism in the Bile Acid Receptor Farnesoid X Receptor Is Associated with Decreased Hepatic Target Gene Expression

Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2)

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