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Synthesis of the phorboxazoles-potent, architecturally novel marine natural products

Journal of antibiotics, 2016-04, Vol.69 (4), p.220-252

2016

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Development of single step drilling technology for multilayer metallic-composite stacks using uncoated and PVD coated carbide tools

Journal of manufacturing processes, 2018-01, Vol.31, p.286-300

2018

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Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine

Scientific reports, 2017-10, Vol.7 (1), p.13432-15, Article 13432

2017

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A probabilistic framework for online structural health monitoring: active learning from machining data streams

Journal of physics. Conference series, 2019-07, Vol.1264 (1), p.12028

2019

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Enantioselective Total Synthesis of CannabinoidsA Route for Analogue Development

Organic letters, 2018-01, Vol.20 (2), p.381-384

2018

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Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp

International journal for parasitology, 2022-10, Vol.52 (11), p.733-744

2022

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Enantioselective Total Synthesis of the Antitumor Macrolide Rhizoxin D

Journal of organic chemistry, 2003-05, Vol.68 (11), p.4215-4234

2003

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The Asymmetric Baylis−Hillman Reaction

Journal of the American Chemical Society, 1997-05, Vol.119 (18), p.4317-4318

1997

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In situ analysis of PCBN cutting tool materials during thermo-mechanical loading using synchrotron radiation

Production engineering (Berlin, Germany), 2018-06, Vol.12 (3-4), p.535-546

2018

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Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome

Cell chemical biology, 2024-04, Vol.31 (4), p.729-742.e13

2024

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Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation

ACS chemical biology, 2023-05, Vol.18 (5), p.1124-1135

2023

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Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

ACS chemical biology, 2018-08, Vol.13 (8), p.2288-2299

2018

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Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Journal of medicinal chemistry, 2013-03, Vol.56 (6), p.2218-2234

2013

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An Unexpected Rate AccelerationPractical Improvements in the Baylis−Hillman Reaction

Journal of organic chemistry, 1997-03, Vol.62 (5), p.1521-1522

1997

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Absolute Configuration of Phorboxazoles A and B from the Marine Sponge Phorbas sp. 1. Macrolide and Hemiketal Rings

Journal of the American Chemical Society, 1996-10, Vol.118 (39), p.9422-9423

1996

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Characterization of Arylalkylamine N‑Acyltransferase from Tribolium castaneum: An Investigation into a Potential Next-Generation Insecticide Target

ACS chemical biology, 2020-02, Vol.15 (2), p.513-523

2020

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Identification and Characterization of Novel Bronchodilator Agonists Acting at Human Airway Smooth Muscle Cell TAS2R5

ACS pharmacology & translational science, 2020-12, Vol.3 (6), p.1069-1075

2020

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Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase γ Inhibitors

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.5467-5482

2012

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Access to in-patient stroke services and multidisciplinary team (MDT) rehabilitation: current demands and capacity

Irish medical journal, 2014-06, Vol.107 (6), p.171-173

2014

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Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer

Clinical cancer research, 2003-08, Vol.9 (8), p.2965-2972

2003

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Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases

ACS infectious diseases, 2023-11, Vol.9 (11), p.2190-2201

2023

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Identification of a Hit Series of Antileishmanial Compounds through the Use of Mixture-Based Libraries

ACS medicinal chemistry letters, 2017-08, Vol.8 (8), p.802-807

2017

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Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs

Journal of enzyme inhibition and medicinal chemistry, 2016-07, Vol.31 (4), p.551-562

2016

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A Unified Total Synthesis of the Immunomodulators (−)-Rapamycin and (−)-27-Demethoxyrapamycin: Construction of the C(21−42) Perimeters

Journal of the American Chemical Society, 1997-02, Vol.119 (5), p.947-961

1997

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Synthesis of the phorboxazoles-potent, architecturally novel marine natural products

Development of single step drilling technology for multilayer metallic-composite stacks using uncoated and PVD coated carbide tools

Structural and Mechanistic Analysis of Drosophila melanogaster Agmatine N-Acetyltransferase, an Enzyme that Catalyzes the Formation of N-Acetylagmatine

A probabilistic framework for online structural health monitoring: active learning from machining data streams

Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba

Enantioselective Total Synthesis of CannabinoidsA Route for Analogue Development

Alkyne modified purines for assessment of activation of Plasmodium vivax hypnozoites and growth of pre-erythrocytic and erythrocytic stages in Plasmodium spp

Enantioselective Total Synthesis of the Antitumor Macrolide Rhizoxin D

The Asymmetric Baylis−Hillman Reaction

In situ analysis of PCBN cutting tool materials during thermo-mechanical loading using synchrotron radiation

Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome

Benzothiazole Substitution Analogs of Rhodacyanine Hsp70 Inhibitors Modulate Tau Accumulation

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

Discovery of a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR)

An Unexpected Rate AccelerationPractical Improvements in the Baylis−Hillman Reaction

Absolute Configuration of Phorboxazoles A and B from the Marine Sponge Phorbas sp. 1. Macrolide and Hemiketal Rings

Characterization of Arylalkylamine N‑Acyltransferase from Tribolium castaneum: An Investigation into a Potential Next-Generation Insecticide Target

Identification and Characterization of Novel Bronchodilator Agonists Acting at Human Airway Smooth Muscle Cell TAS2R5

Discovery of a Novel Series of Potent and Orally Bioavailable Phosphoinositide 3-Kinase γ Inhibitors

Access to in-patient stroke services and multidisciplinary team (MDT) rehabilitation: current demands and capacity

Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: An endothelin receptor antagonist for refractory prostate cancer

Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases

Identification of a Hit Series of Antileishmanial Compounds through the Use of Mixture-Based Libraries

Inactivation of peptidylglycine α-hydroxylating monooxygenase by cinnamic acid analogs

A Unified Total Synthesis of the Immunomodulators (−)-Rapamycin and (−)-27-Demethoxyrapamycin: Construction of the C(21−42) Perimeters

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