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Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses

Journal of thrombosis and haemostasis, 2005-04, Vol.3 (4), p.733-741

2005

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Coagulation factor Xa inhibition: biological background and rationale

Current topics in medicinal chemistry, 2001-06, Vol.1 (2), p.151-159

Leadley, Jr, R J

2001

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Recent advances in the discovery and development of direct coagulation factor Xa inhibitors

Current pharmaceutical design, 2003-01, Vol.9 (28), p.2337-2347

2003

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Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs

American journal of physiology. Regulatory, integrative and comparative physiology, 1988-12, Vol.255 (6), p.1064-R1068

1988

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Inhibition and reversal of platelet‐rich arterial thrombus in vivo: direct vs. indirect factor Xa inhibition

Journal of thrombosis and haemostasis, 2004-12, Vol.2 (12), p.2162-2169

2004

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Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro

Journal of thrombosis and haemostasis, 2006-04, Vol.4 (4), p.834-841

2006

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Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents

Journal of pharmacological and toxicological methods, 2000-03, Vol.43 (2), p.101-116

2000

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Inhibition of repetitive thrombus formation in the stenosed canine coronary artery by enoxaparin, but not by unfractionated heparin

Arteriosclerosis, thrombosis, and vascular biology, 1998-06, Vol.18 (6), p.908-914

1998

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RPR120844, a novel, specific inhibitor of coagulation factor Xa inhibits venous thrombosis in the rabbit

Thrombosis and haemostasis, 1999-01, Vol.81 (1), p.157-160

1999

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Pharmacological Characterization of a Novel Factor Xa Inhibitor, FXV673

Thrombosis research, 2001-08, Vol.103 (4), p.309-324

2001

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In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737

Thrombosis research, 2000-07, Vol.99 (1), p.71-82

2000

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Atrial stretch increases sodium excretion independently of release of atrial peptides

American journal of physiology. Regulatory, integrative and comparative physiology, 1986-05, Vol.250 (5), p.946-R950

1986

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Design of a New Class of Orally Active Fibrinogen Receptor Antagonists

Journal of medicinal chemistry, 1998-07, Vol.41 (14), p.2492-2502

1998

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Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa

Journal of medicinal chemistry, 1998-02, Vol.41 (4), p.437-450

1998

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Pharmacodynamic Activity and Antithrombotic Efficacy of RPR120844, a Novel Inhibitor of Coagulation Factor Xa

Journal of cardiovascular pharmacology, 1999-12, Vol.34 (6), p.791-799

1999

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Comparison of enoxaparin, hirulog, and heparin as adjunctive antithrombotic therapy during thrombolysis with rtPA in the stenosed canine coronary artery

Thrombosis and haemostasis, 1997-10, Vol.78 (4), p.1278-1285

1997

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Hemodynamic and renal effects of low-dose infusions of atrial peptide in awake dogs

American journal of physiology. Regulatory, integrative and comparative physiology, 1988-02, Vol.254 (2), p.161-R169

1988

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Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (18), p.2753-2758

1999

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Inhibition of thrombus formation by endothelin-1 in canine models of arterial thrombosis

Thrombosis and haemostasis, 1995-12, Vol.74 (6), p.1583-1590

1995

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Epidural Morphine With Butorphanol for Postoperative Analgesia After Cesarean Delivery

Anesthesia and analgesia, 1991-01, Vol.72 (1), p.53-57

1991

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Growth Factor-Induced Modulation of Endothelin-1 Binding to Human Smooth-Muscle Cells

Journal of cardiovascular pharmacology, 1993, Vol.22 Suppl 8 (Supplement 8), p.S125-S127

1993

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Ventricular receptors stimulate vasopressin release during hemorrhage

American journal of physiology. Regulatory, integrative and comparative physiology, 1988-02, Vol.254 (2), p.204-R211

1988

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Contribution of Cardiac and Arterial Baroreceptors to Enhanced Vasopressin Release During Hemorrhage with Autonomic Blockade

Experimental biology and medicine (Maywood, N.J.), 1995-04, Vol.208 (4), p.361-369

1995

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Non-hemostatic activity of coagulation factor Xa: potential implications for various diseases

Current Opinion in Pharmacology, 2001-04, Vol.1 (2), p.169-175

2001

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Anti-thrombotic activity of RG13965, a novel platelet fibrinogen receptor antagonist

Thrombosis research, 1996-06, Vol.82 (6), p.495-507

1996

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Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses

Coagulation factor Xa inhibition: biological background and rationale

Recent advances in the discovery and development of direct coagulation factor Xa inhibitors

Cardiovascular, renal, and endocrine responses to intravenous endothelin in conscious dogs

Inhibition and reversal of platelet‐rich arterial thrombus in vivo: direct vs. indirect factor Xa inhibition

Inhibitors of blood coagulation factors Xa and IIa synergize to reduce thrombus weight and thrombin generation in vivo and in vitro

Contribution of in vivo models of thrombosis to the discovery and development of novel antithrombotic agents

Inhibition of repetitive thrombus formation in the stenosed canine coronary artery by enoxaparin, but not by unfractionated heparin

RPR120844, a novel, specific inhibitor of coagulation factor Xa inhibits venous thrombosis in the rabbit

Pharmacological Characterization of a Novel Factor Xa Inhibitor, FXV673

In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737

Atrial stretch increases sodium excretion independently of release of atrial peptides

Design of a New Class of Orally Active Fibrinogen Receptor Antagonists

Identification and Initial Structure−Activity Relationships of a Novel Class of Nonpeptide Inhibitors of Blood Coagulation Factor Xa

Pharmacodynamic Activity and Antithrombotic Efficacy of RPR120844, a Novel Inhibitor of Coagulation Factor Xa

Comparison of enoxaparin, hirulog, and heparin as adjunctive antithrombotic therapy during thrombolysis with rtPA in the stenosed canine coronary artery

Hemodynamic and renal effects of low-dose infusions of atrial peptide in awake dogs

Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors

Inhibition of thrombus formation by endothelin-1 in canine models of arterial thrombosis

Epidural Morphine With Butorphanol for Postoperative Analgesia After Cesarean Delivery

Growth Factor-Induced Modulation of Endothelin-1 Binding to Human Smooth-Muscle Cells

Ventricular receptors stimulate vasopressin release during hemorrhage

Contribution of Cardiac and Arterial Baroreceptors to Enhanced Vasopressin Release During Hemorrhage with Autonomic Blockade

Non-hemostatic activity of coagulation factor Xa: potential implications for various diseases

Anti-thrombotic activity of RG13965, a novel platelet fibrinogen receptor antagonist

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