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Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations

Xenobiotica, 2007-10, Vol.37 (10-11), p.1196-1224

2007

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Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro

American Journal of Physiology: Cell Physiology, 2013-06, Vol.304 (11), p.C1053-C1063

2013

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Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation

European Journal of Pharmaceutical Sciences, 2001-07, Vol.13 (4), p.343-368

LeCluyse, Edward L

2001

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Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells

Archives of toxicology, 2000-08, Vol.74 (6), p.289-299

2000

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Characterization of a human thyroid microtissue model for testing thyroid disrupting chemicals

Frontiers in toxicology, 2024-07, Vol.6, p.1408808

2024

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The evolving microenvironment of the human hepatocyte: Healthy vs. cirrhotic liver vs. isolated cells

Tissue & cell, 2020-02, Vol.62, p.101310, Article 101310

2020

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Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics

Chemico-biological interactions, 2001-05, Vol.134 (3), p.283-289

LeCluyse, Edward L

2001

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Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions

Cell and tissue research, 2001-10, Vol.306 (1), p.85-99

2001

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Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes

Toxicology in vitro, 2002-02, Vol.16 (1), p.89-99

2002

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SOC-III-08 Inhibition of thyroxin hormone synthesis with thyroid disrupting chemicals in primary human thyrocytes

Toxicology letters, 2022-09, Vol.368, p.S45

2022

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Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration

American Journal of Physiology: Cell Physiology, 1994-06, Vol.266 (6), p.C1764-C1774

1994

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OPTIMIZATION OF CULTURE CONDITIONS FOR DETERMINING HEPATOBILIARY DISPOSITION OF TAUROCHOLATE IN SANDWICH-CULTURED RAT HEPATOCYTES

In vitro cellular & developmental biology. Animal, 2001-06, Vol.37 (6), p.380-385

2001

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The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

Molecular endocrinology (Baltimore, Md.), 2000-01, Vol.14 (1), p.27-39

2000

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Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

Journal of biochemical and molecular toxicology, 2000, Vol.14 (4), p.177-188

2000

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Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

Xenobiotica, 2000, Vol.30 (3), p.273-284

2000

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Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats

Drug metabolism and disposition, 1999-06, Vol.27 (6), p.637

1999

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Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

Drug metabolism and disposition, 2003-04, Vol.31 (4), p.421-431

2003

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In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone

Clinical pharmacology and therapeutics, 2000-10, Vol.68 (4), p.356-366

2000

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Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers

Journal of pharmaceutical sciences, 1999-11, Vol.88 (11), p.1161-1168

1999

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Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration

American journal of physiology: Gastrointestinal and liver physiology, 1999-07, Vol.277 (1), p.G12-G21

1999

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Hepatic Progenitors and Strategies for Liver Cell Therapies

Annals of the New York Academy of Sciences, 2001-11, Vol.944 (1), p.398-419

2001

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Application of cDNA microarray to the study of arsenic-induced liver diseases in the population of Guizhou, China

Toxicological sciences, 2001, Vol.59 (1), p.185-192

2001

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S26-01: Evaluation of Microphysiological Systems combining skin models and systemic organs to elucidate the influence of application scenarios on the bioavailability, metabolic fate and biological effects of cosmetic chemicals

Toxicology letters, 2023-09, Vol.384, p.S54

2023

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S26 | Translational Advanced Platforms: S26-01 Evaluation of Microphysiological Systems combining skin models and systemic organs to elucidate the influence of application scenarios on the bioavailability, metabolic fate and biological effects of cosmetic chemicals

Toxicology letters, 2023-09, Vol.384, p.S52-S52

2023

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Cells, Cultured
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Toxicology
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Hepatocytes - Drug Effects
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Pharmacology. Drug Treatments
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Hepatocytes - Metabolism
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Liver - Cytology
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Fundamental And Applied Biological Sciences. Psychology
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Induction of hepatic cytochrome P450 enzymes: methods, mechanisms, recommendations, and in vitro-in vivo correlations

Hemodynamic flow improves rat hepatocyte morphology, function, and metabolic activity in vitro

Human hepatocyte culture systems for the in vitro evaluation of cytochrome P450 expression and regulation

Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells

Characterization of a human thyroid microtissue model for testing thyroid disrupting chemicals

The evolving microenvironment of the human hepatocyte: Healthy vs. cirrhotic liver vs. isolated cells

Pregnane X receptor: molecular basis for species differences in CYP3A induction by xenobiotics

Regulation of cell morphology and cytochrome P450 expression in human hepatocytes by extracellular matrix and cell-cell interactions

Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes

SOC-III-08 Inhibition of thyroxin hormone synthesis with thyroid disrupting chemicals in primary human thyrocytes

Formation of extensive canalicular networks by rat hepatocytes cultured in collagen-sandwich configuration

OPTIMIZATION OF CULTURE CONDITIONS FOR DETERMINING HEPATOBILIARY DISPOSITION OF TAUROCHOLATE IN SANDWICH-CULTURED RAT HEPATOCYTES

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

Expression and regulation of cytochrome P450 enzymes in primary cultures of human hepatocytes

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

Correlation of biliary excretion in sandwich-cultured rat hepatocytes and in vivo in rats

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone

Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers

Biliary excretion in primary rat hepatocytes cultured in a collagen-sandwich configuration

Hepatic Progenitors and Strategies for Liver Cell Therapies

Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins, and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism, Enzyme Induction, Transporter, Clearance, and Hepatotoxicity Studies

Application of cDNA microarray to the study of arsenic-induced liver diseases in the population of Guizhou, China

S26-01: Evaluation of Microphysiological Systems combining skin models and systemic organs to elucidate the influence of application scenarios on the bioavailability, metabolic fate and biological effects of cosmetic chemicals

S26 | Translational Advanced Platforms: S26-01 Evaluation of Microphysiological Systems combining skin models and systemic organs to elucidate the influence of application scenarios on the bioavailability, metabolic fate and biological effects of cosmetic chemicals

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